CSTL CASTLE BIOSCIENCES INC

BEARISH Impact: 5/10 Institutional Cluster
Horizon weeks Processed 2d ago
Institutional cluster: 2 buyers, 5 sellers (bearish)

Executive Summary

Institutional cluster for CSTL reveals 5 sellers (notably Citadel trimming 71.8% of its stake) vs 2 passive buyers, resulting in net selling of ~$11M. Quant funds leading the exit suggests caution despite bullish analyst sentiment.

Key Financial Metrics

Direction
distributing
Buy Value
$7.4M
Sell Value
$30.8M
Net Flow
-$11.0M

Institutional Positions

Net institutional flow: -$11.0M

▲ Buyers (2)

InstitutionActionChangePosition ValueValue Δ
Morgan Stanley ADD +60.9% $6.1M $2.7M
Invesco ADD +38.1% $1.3M $446.0K

▼ Sellers (5)

InstitutionActionChangePrev ValueValue Δ
D.E. Shaw TRIM -37.5% $3.0M -$917.2K
Citadel TRIM -71.8% $18.1M -$12.4M
Ubs Am, A Distinct Business Un TRIM -44.1% $2.1M -$789.6K
Ameriprise Financial TRIM -31.2% $7.6M -$1.8M
Barclays TRIM -33.4% $2.0K $1.7M

Actionable Insight

Institutional cluster shows significant net selling led by quantitative funds (Citadel, D.E. Shaw). Despite bullish analyst consensus, this selling pressure flags potential near-term weakness. Monitor for further insider activity or guidance changes.

Key Facts

  • 5 institutions reduced positions by $14.2M while 2 passive funds added $3.2M
  • Net institutional selling of approximately $11.0M
  • Citadel cut 71.8% of its stake, selling $12.4M worth
  • D.E. Shaw reduced by 37.5%, selling $917K
  • Only passive buyers (Morgan Stanley, Invesco) added shares

Financial Impact

5 institutions reduced holdings by $14.2M while 2 passive funds added $3.2M, resulting in net institutional selling of approximately $11.0M.

institutional ownershipsentiment

Risk Factors

  • 13F data is 45+ days stale; positions may have been unwound further
  • Passive buying could offset selling pressure
  • Strong analyst consensus may be overoptimistic

Market Snapshot

Exchange
Nasdaq
Sector
Services-Medical Laboratories
Analyst Consensus
93% bullish (14 analysts)

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-CSTL-2025-Q3
11 reports for CSTL
Performance horizon
83% Hit rate 5 of 6 directional calls best @ T+60▲ +24.87%Mar 5, 2026
Filters
Rows
Reports for CSTL — sortable, filterable
Type Now
Jun 11, 2026
2d ago
Institutional Cluster
BEARISH ★ 5/10
$20.89 awaiting T+1awaiting T+1
Jun 1, 2026
11d ago
144
NEUTRAL ★ 4/10
$19.71 $20.39▲ +3.45%▲ +4.17%
May 7, 2026
5w ago
144
NEUTRAL ★ 3/10
$19.83 $19.04▼ −3.98%▼ −4.22%
Apr 8, 2026
9w ago
DEFA14A
NEUTRAL ★ 3/10
$25.19 $23.43▼ −6.99%▼ −7.56%
Mar 13, 2026
13w ago
Press Release
BULLISH ★ 7/10
$25.56 $25.83▲ +1.06%▲ +0.03%
Mar 12, 2026
13w ago
Insider Cluster
BEARISH ★ 6/10
$25.32 $25.56▼ −0.95%▼ −1.55%
Mar 12, 2026
13w ago
Insider Cluster
BEARISH ★ 7/10
$25.32 $25.56▼ −0.95%▼ −1.55%
Mar 9, 2026
13w ago
Press Release
BULLISH ★ 7/10
$27.02 $26.60▼ −1.55%▼ −1.37%
Mar 5, 2026
14w ago
Insider Cluster
BEARISH ★ 7/10
$27.91 $27.12▲ +2.83%▲ +1.52%
Mar 5, 2026
14w ago
Insider Cluster
BEARISH ★ 5/10
$27.91 $27.12▲ +2.83%▲ +1.52%
Showing 10 of 11

US Market Status

Market Closed — Opens Mon (44h 26m)

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