IMNM Immunome Inc.

BULLISH Impact: 3/10 ANALYST-UPGRADE
Processed 17d 19h ago SEC analyst-IMNM-barclays-20260528
Barclays initiates coverage on IMNM at Overweight
Latest settled — T+5d
IMNM ▼ -12.11% at T+5d
LONG call ✗ call lost -12.11% · α vs SPY -12.06% · entry $22.54 → $19.81
Next anchor: T+20d in 11d
Last close $18.38 (close Jun 12) · -18.46% from $22.54 entry
Entry anchored
May 28, 10:03 AM ET
via Databento tick
T+1d
-3.15%
call -3.15% · α -3.39%
$21.83
settled 17d ago
T+5d
-12.11%
call -12.11% · α -12.06%
$19.81
settled 11d ago
T+20d
call — · α —
in 11d
T+60d
call — · α —
in 2mo

Price Chart

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Executive Summary

Barclays initiated coverage on Immunome Inc. (IMNM) at Overweight with a $36 price target, implying 66% upside from the current $21.66. The call aligns with an overwhelmingly bullish consensus — 95% of 20 analysts rate the stock Buy or Strong Buy, with only one Hold. The mean price target of $35.23 is nearly identical to Barclays' $36, placing the firm in line with the Street. Barclays carries a 54% accuracy rate on 6,762 calls with a +3.9% average return, a solid but not elite track record. EPS revisions have been strongly positive over the past 30 days — 9 upward revisions vs. 1 downward — signaling improving fundamentals. Insider activity shows a notable buy from director Clay B. Siegall ($500K) on March 27 and a $103K buy from Jean Jacques Bienaime on May 15, both bullish signals that converge with the analyst upgrade. Institutional buying is also heavy, with FMR LLC adding 26.8% and Bank of America doubling its position. The bottom line: Barclays' initiation is a consensus-aligned call from a mid-tier firm, but strong insider buying and institutional accumulation add conviction to the bullish thesis.

Impact Score

Base Score
2/7
LLM Adjustment
+1
Final Score
3/10

Consensus & Targets

Buy / Strong Buy
19 (95%)
Hold
1
Sell / Strong Sell
0
Total Analysts
13
Mean PT
$35.23
Median PT
$35.00
High PT
$40.00
Low PT
$30.00
Current Price
$21.66
Implied Upside
+62.7%

Of 20 analysts covering IMNM, 6 rate it Strong Buy, 13 Buy, 1 Hold, 0 Sell, and 0 Strong Sell — a 95% Buy/Strong Buy ratio. The consensus is overwhelmingly bullish, with only a single Hold dissenter. No Sell ratings exist.

Current price: $21.66. Mean target: $35.23 (63% upside). Median: $35.00. High: $40.00 (HC Wainwright). Low: $30.00. Barclays' $36 target sits slightly above the mean and median, in the upper half of the range but not the highest.

Recent Analyst Activity

DateFirmActionRatingPrice Target
2026-05-28 Barclays initiate Overweight $36.00
2026-05-15 Leerink Partners maintain Outperform $33.00
2026-05-13 HC Wainwright & Co. reiterate Buy $40.00
2026-03-04 Craig-Hallum maintain Buy
2026-03-04 Stephens & Co. maintain Overweight
2026-02-12 HC Wainwright & Co. initiate Buy $40.00
2026-01-15 Wedbush reiterate Outperform $31.00
2025-12-16 Lake Street maintain Buy $32.00
2025-12-16 Evercore ISI Group maintain Outperform $40.00
2025-12-16 Guggenheim maintain Buy $35.00

Over the past 30 days, 9 EPS revisions up and 1 down for the current fiscal year, and 9 up and 0 down for the current quarter — a strong upward revision trend. Analyst actions show 1 upgrade (Barclays initiation) and 0 downgrades in the past 30 days. The momentum is clearly bullish.

Firm Track Record — Barclays

Barclays accuracy: 54% on 6762 calls | avg return: 3.9%

Industry benchmark: mean 51% ± 11%. Top tier: ≥61% (mean + 1σ). Based on 7 firms with ≥5 scored calls.

FirmAccuracyCallsAvg Returnvs Average
JP Morgan 100% 2/2 32.2% top tier
Stephens & Co. 67% 2/3 3.3% top tier
Evercore ISI Group 50% 1/2 33.3% below average
Lake Street 50% 1/2 7.7% below average
Guggenheim 50% 2/4 11.8% below average
Piper Sandler 33% 1/3 -6.5% below average
Wedbush 25% 1/4 -19% below average

Barclays has a 54% accuracy rate on 6,762 scored calls with a +3.9% average return — a solid, average-performing firm. Among firms covering IMNM, top-tier performers include JP Morgan (100% on 2 calls, +32.2% avg return) and Stephens & Co. (67% on 3 calls, +3.3%). Weakest is Wedbush (25% on 4 calls, -19% avg return). Barclays' initiation is in line with its typical performance.

Earnings Estimates

PeriodEPS Est.EPS RangeRevenueRevisions (7d)
0y $-2.14 $-2.45 — $-1.84 $2.5M ↑9 ↓0
0q $-0.51 $-0.64 — $-0.41 $166.7K ↑9 ↓0
+1q $-0.56 $-0.73 — $-0.48 $166.7K ↑9 ↓0
+1y $-2.00 $-2.58 — $-1.25 $81.6M ↑6 ↓0

Cross-Platform Signals

Insider Trades (90d)
2 buys / 3 sells
Institutional
FMR LLC — add (26.8%)
Institutional
BANK OF AMERICA CORP /DE/ — doubled (120%)
Institutional
WELLS FARGO & COMPANY/MN — doubled (110.3%)
Short Interest
Short: 426,157 | Exempt: 30 | TRF Vol: 588,868 | Short Ratio: 72.4% | Off-exchange volume (dark pool + OTC)

Insider trades show two notable buys: director Clay B. Siegall bought $500K on March 27 and Jean Jacques Bienaime bought $103K on May 15 — both bullish signals that converge with the analyst upgrade. Insider sales (Higgins $204K, Rosett $1.4M, Wagenheim $582K) are present but are not clustered and may be liquidity-driven. Institutional activity is heavily bullish: FMR LLC added 26.8% ($355M position), Bank of America doubled (+120%), Wells Fargo doubled (+110%). One exit by Renaissance Technologies is a minor divergence. Short interest is elevated at 72.4% of float, which could fuel a squeeze if positive catalysts emerge. The convergence of insider buys, institutional accumulation, and analyst bullishness is a strong signal.

Actionable Insight

The combination of a 95% bullish consensus, strong insider buying, heavy institutional accumulation, and upward EPS revisions makes IMNM a high-conviction long. The elevated short interest (72.4%) adds squeeze potential. Traders should consider adding to positions on any pullback, with a target near the $35-$36 consensus.

Documents Analyzed

Report based on filing metadata.

7 reports for IMNM
Performance horizon

Track record builds as more directional reports settle.

Filters
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Reports for IMNM — sortable, filterable
Type Now
May 28, 2026
17d ago
ANALYST-UPGRADE
BULLISH ★ 3/10
$22.54 $19.81▼ −12.11%▼ −12.06%$18.38 (−18.46%)
May 16, 2026
29d ago
ANALYST-UPGRADE
BULLISH ★ 1/10
$22.44 $21.50▼ −4.19%▼ −5.39%$18.38 (−18.09%)
May 12, 2026
4w ago
8-K
BULLISH ★ 7/10
$22.20 $19.66▼ −11.44%▼ −10.28%$18.38 (−17.21%)
Apr 24, 2026
7w ago
DEFA14A
NEUTRAL ★ 2/10
$23.49 $23.33▼ −0.68%▼ −1.08%$18.38 (−21.75%)
Apr 16, 2026
8w ago
ANALYST-UPGRADE
MIXED ★ 7/10
$23.26 $22.99▼ −1.16%▼ −2.14%$18.38 (−20.98%)
Mar 23, 2026
12w ago
Insider Cluster
MIXED ★ 5/10
$20.75 $19.30▼ −6.99%▼ −3.42%$18.38 (−11.42%)
Mar 23, 2026
12w ago
Insider Cluster
MIXED ★ 5/10
$20.75 $19.30▼ −6.99%▼ −3.42%$18.38 (−11.42%)
Showing 7 of 7

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