LYEL Lyell Immunopharma, Inc.

BULLISH Impact: 8/10 Insider Cluster (2 insiders)
Horizon weeks Filed Mar 6, 2026 Processed 3mo ago
Insider cluster: 2 insiders, $25.0M total
Final — all horizons settled through T+60d ⚠ clustered
LYEL ▼ -23.64% at T+60d
LONG call ✗ call lost -23.64% · α vs SPY -36.42% · entry $22.46 → $17.15
Last close $13.50 (close Jun 12) · -39.89% from $22.46 entry
Entry anchored
Mar 5, 03:59 PM ET
via Databento tick
T+1d
+13.54%
call +13.54% · α +12.69%
$25.50
settled 3mo ago
T+5d
-5.39%
call -5.39% · α -3.86%
$21.25
settled 3mo ago
T+20d
-3.43%
call -3.43% · α -1.38%
$21.69
settled 2mo ago
T+60d
-23.64%
call -23.64% · α -36.42%
$17.15
settled 14d ago

Price Chart

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Executive Summary

Two funds affiliated with ARCH Venture Partners collectively purchased nearly $25 million worth of Lyell Immunopharma shares in open-market transactions at $25.61 per share. This represents a significant, coordinated investment by a major biotech venture firm, signaling strong confidence in the company's future prospects.

Key Financial Metrics

Direction
buying
Total Value
$25.0M
Insiders
2

Actionable Insight

This level of coordinated buying by a sophisticated biotech investor like ARCH Venture Partners is highly unusual and suggests strong conviction ahead of potential clinical or strategic developments. Traders should watch for upcoming catalysts such as trial readouts, partnerships, or funding news.

Key Facts

  • ARCH Venture Partners IX, LLC purchased 488,090 shares at $25.61 for $12,500,000
  • ARCH Venture Fund XIII, L.P. purchased 488,090 shares at $25.61 for $12,500,000
  • Total open-market purchases: $25.0M across two affiliated funds
  • Transactions occurred on 2026-03-06 in a single day
  • Combined purchase represents approximately 5.2% of Lyell's $477M market cap

Financial Impact

$25.0 million in insider buying, equivalent to 5.2% of market capitalization

market sentimentshare ownershipinvestor confidence

Risk Factors

  • The purchases were made by affiliated funds, not company insiders (executives or directors), so this reflects investor confidence rather than direct management sentiment
  • Biotech stocks are inherently volatile and sensitive to clinical trial outcomes

Market Snapshot

Exchange
Nasdaq

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (2 trades, 7d window)cluster-LYEL-1773088624224
10 reports for LYEL
Performance horizon
Filters
Rows
Reports for LYEL — sortable, filterable
Type Now
Jun 12, 2026
2d ago
Press Release
NEUTRAL ★ 4/10
$13.32 awaiting T+20awaiting T+20$13.50 (+1.39%)
Jun 8, 2026
6d ago
Press Release
BULLISH ★ 7/10
$11.94 awaiting T+20awaiting T+20$13.50 (+13.11%)
Jun 4, 2026
10d ago
Press Release
NEUTRAL ★ 3/10
$13.02 awaiting T+20awaiting T+20$13.50 (+3.73%)
Apr 24, 2026
7w ago
DEFA14A
NEUTRAL ★ 3/10
$22.62 $16.37▼ −27.63%▼ −32.59%$13.50 (−40.32%)
Apr 15, 2026
8w ago
EFFECT
NEUTRAL ★ 2/10
$23.84 $19.25▼ −19.25%▼ −25.30%$13.50 (−43.37%)
Apr 3, 2026
10w ago
S-3
NEUTRAL ★ 2/10
$21.69 $20.72▼ −4.47%▼ −13.45%$13.50 (−37.76%)
Mar 12, 2026
13w ago
Press Release
MIXED ★ 6/10
$21.25 $24.80▲ +16.71%▲ +13.12%$13.50 (−36.47%)
Mar 9, 2026
13w ago
Press Release
NEUTRAL ★ 5/10
$25.50 $21.78▼ −14.59%▼ −11.78%$13.50 (−47.06%)
Mar 6, 2026
14w ago
Insider Cluster
BULLISH ★ 8/10
$22.46 $21.69▼ −3.43%▼ −1.38%$13.50 (−39.89%)
Feb 28, 2026
15w ago
Institutional Cluster
MIXED ★ 5/10
$24.10 $19.29▼ −19.96%▼ −12.02%$13.50 (−43.98%)
Showing 10 of 10

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