MAZE Maze Therapeutics, Inc.
Executive Summary
Three mega-passive institutional investors (Vanguard, BlackRock, Morgan Stanley) collectively doubled their positions in Maze Therapeutics during Q3 2025, adding $61.2M in new holdings to reach $74.3M total. This is a passive index-driven accumulation signal, not an active fundamental thesis, and follows a period of poor historical stock performance with zero winning calls at T+20.
Key Financial Metrics
Institutional Positions
Net institutional flow: $61.2M
▲ Buyers (3)
| Institution | Action | Change | Position Value | Value Δ |
|---|---|---|---|---|
| Vanguard | DOUBLED | +218.1% | $34.6M | $29.5M |
| BlackRock | DOUBLED | +114.1% | $34.1M | $26.6M |
| Morgan Stanley | DOUBLED | +569.5% | $5.5M | $5.1M |
Actionable Insight
The cluster is entirely passive/index-driven (Vanguard, BlackRock, Morgan Stanley), likely reflecting index rebalancing or ETF inflows rather than a fundamental thesis. With MAZE's historical T+20 performance deeply negative and zero prior winning calls, this passive accumulation does not signal near-term upside. Monitor for active manager 13F filings or insider buying for a more reliable signal.
Key Facts
- 3 institutional buyers, 0 sellers in Q3 2025
- Aggregate net buying: $61.2M (from $13.0M to $74.3M)
- Vanguard doubled shares (+218.1%), BlackRock doubled (+114.1%), Morgan Stanley increased 569.5%
- All three buyers are mega-passive/index funds — not active managers
- Historical MAZE reports show 0% win rate at T+20 (n=6 settled), avg T+20 return -13.45%
Financial Impact
3 institutions accumulated $61.2M in new positions, bringing total disclosed holdings to $74.3M
Risk Factors
- Passive buying provides no fundamental validation — may be mechanically reversed in next rebalance
- Historical MAZE reports show consistent negative T+20 returns regardless of filing type
- No active manager participation suggests lack of conviction from informed capital
Market Snapshot
Documents Analyzed
This report is based on 1 institutional 13F filing from SEC EDGAR.
| Document | Accession Number |
|---|---|
| INST-CLUSTER Data (Synthetic) | inst-cluster-MAZE-2025-Q3 |
Track record builds as more directional reports settle.
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
|
Jun 11, 2026
9d ago
|
Institutional Cluster
| $24.09 $24.84 | ▲ +3.11% | ▲ +2.68% | — |
|
Jun 3, 2026
17d ago
|
Insider Cluster
| $25.40 $24.09 | ▲ +5.16% | ▲ +2.60% | — |
|
May 22, 2026
29d ago
|
8-K
| $26.35 $24.29 | ▼ −7.82% | ▼ −9.03% | — |
|
May 18, 2026
4w ago
|
Insider Cluster
| $24.46 $26.05 | ▲ +6.50% | ▲ +4.20% | — |
|
May 12, 2026
5w ago
|
8-K
| $26.96 $24.46 | ▼ −9.27% | ▼ −8.12% | — |
|
May 12, 2026
5w ago
|
Press Release
| $26.96 $24.46 | ▼ −9.27% | ▼ −8.12% | — |
|
Apr 22, 2026
8w ago
|
424B5
| $26.01 $25.68 | ▼ −1.27% | ▼ −2.75% | — |
|
Mar 25, 2026
12w ago
|
Press Release
| $31.73 $29.05 | ▼ −8.45% | ▼ −8.20% | — |
US Market Status
Subscribe to SecBot
Get Real-Time SEC Filing Intelligence
Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.
Try SecBot Free Coming soon: SecBot Pro with alerts, watchlists, and API access