MBRX Moleculin Biotech, Inc.

NEUTRAL Impact: 4/10 8-K
Horizon days Filed May 22, 2026 Processed 18d 10h ago SEC 0001437749-26-018242
8-K context-dependent: Items 7.01
Latest settled — T+5d
MBRX ▲ +7.76% at T+5d
NEUTRAL call ✓ call won +7.76% · α vs SPY +6.67% · entry $2.45 → $2.64
Next anchor: T+20d in 13d
Last close $2.47 (close Jun 8) · +0.82% from $2.45 entry
Entry anchored
May 22, 03:59 PM ET
via Databento tick
T+1d
+9.18%
call +9.18% · α +9.23%
$2.68
settled 15d ago
T+5d
+7.76%
call +7.76% · α +6.67%
$2.64
settled 9d ago
T+20d
call — · α —
in 13d
T+60d
call — · α —
in 2mo

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Executive Summary

Moleculin announced that an abstract on pooled cardiac safety data for Annamycin has been accepted for a poster presentation at the 2026 ASCO Annual Meeting. The data show no cardiotoxicity signals in 90 patients, supporting the drug's safety profile. This is a routine clinical update with no new efficacy or financial data.

Actionable Insight

Monitor ASCO presentation for detailed data; no immediate trading catalyst. The safety data reinforces Annamycin's profile but does not change near-term fundamentals.

Key Facts

  • Abstract accepted for poster presentation at ASCO 2026 (May 29–June 2, 2026).
  • Pooled cardiac safety data from 90 patients across 5 trials: no statistically significant LVEF change (mean difference -0.12%, p=0.84).
  • Median cumulative Annamycin dose 660 mg/m² (range 210–2,970 mg/m²), exceeding conventional anthracycline limits.
  • No evidence of drug-induced cardiotoxicity by ECG, biomarkers, or adverse events.
  • Previously reported Phase 1b/2 data: 50% CR, 60% CRc, median OS 12.39 months.

Financial Impact

No financial impact disclosed.

Risk Factors

  • Clinical trial risks for ongoing Phase 2b/3 MIRACLE trial.
  • Need for additional financing as noted in forward-looking statements.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
89% bullish (9 analysts)

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001437749-26-018242
Exhibit: ex_967284.htm0001437749-26-018242
Document: 0001437749-26-018242-index-headers.html0001437749-26-018242
Document: 0001437749-26-018242-index.html0001437749-26-018242
Document: 0001437749-26-018242.txt0001437749-26-018242
13 reports for MBRX
Performance horizon
50% Hit rate 3 of 6 directional calls best @ T+5▲ +9.81%May 13, 2026
Filters
Rows
Reports for MBRX — sortable, filterable
Type Now
Jun 5, 2026
4d ago
8-K
BULLISH ★ 5/10
$2.58 awaiting T+5awaiting T+5$2.47 (−4.26%)
May 29, 2026
11d ago
8-K
BULLISH ★ 6/10
$2.79 $2.46▼ −11.83%▼ −11.54%$2.47 (−11.47%)
May 26, 2026
14d ago
8-K
NEUTRAL ★ 3/10
$2.45 $2.64▲ +7.76%▲ +6.67%$2.47 (+0.82%)
May 22, 2026
18d ago
8-K
NEUTRAL ★ 4/10
$2.45 $2.64▲ +7.76%▲ +6.67%$2.47 (+0.82%)
May 15, 2026
25d ago
8-K
MIXED ★ 6/10
$2.11 $2.39▲ +13.27%▲ +12.31%$2.47 (+17.06%)
May 15, 2026
25d ago
Press Release
BEARISH ★ 6/10
$2.11 $2.39▼ −13.27%▼ −12.31%$2.47 (−17.06%)
May 13, 2026
27d ago
8-K
BULLISH ★ 6/10
$2.14 $2.35▲ +9.81%▲ +10.97%$2.47 (+15.42%)
May 12, 2026
28d ago
8-K
NEUTRAL ★ 3/10
$2.34 $2.09▼ −10.68%▼ −10.76%$2.47 (+5.56%)
May 8, 2026
4w ago
8-K
NEUTRAL ★ 3/10
$2.47 $2.20▼ −10.93%▼ −12.39%$2.47 (+0.00%)
Apr 23, 2026
6w ago
8-K
BULLISH ★ 6/10
$2.54 $2.51▼ −1.18%▼ −2.66%$2.47 (−2.76%)
Showing 10 of 13

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