OSUR ORASURE TECHNOLOGIES INC

MIXED Impact: 6/10 8-K
Horizon weeks Filed Feb 25, 2026 Processed 3mo ago SEC 0001116463-26-000009
8-K Item 2.02: Earnings release
Final — all horizons settled through T+60d
OSUR ▲ +6.82% at T+60d
NEUTRAL call ✓ call won +6.82% · α vs SPY -0.93% · entry $3.08 → $3.29
Currently $4.18 · +35.71% from $3.08 entry
Entry anchored
Feb 25, 03:59 PM ET
via Databento tick
T+1d
+2.27%
call +2.27% · α +2.73%
$3.15
settled 4mo ago
T+5d
-2.92%
call -2.92% · α -1.79%
$2.99
settled 3mo ago
T+20d
-0.32%
call -0.32% · α +6.08%
$3.07
settled 3mo ago
T+60d
+6.82%
call +6.82% · α -0.93%
$3.29
settled 23d ago

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Executive Summary

OraSure Technologies reported a significant decline in Q4 and full-year 2025 revenue, down 29% and 38% respectively, driven by steep drops in its core diagnostics and sample management businesses. Despite the poor financial performance, the company highlighted new FDA submissions for a Chlamydia/Gonorrhea self-test and a urine collection device, and maintained a $40 million share buyback program. The filing presents a mixed picture of deteriorating fundamentals offset by future growth initiatives.

Key Financial Metrics

Revenue
$26.8M
-29.0% YoY
Adj. EPS
$-0.19
GAAP: $-0.27
Guidance
$26 million to $29 million
Gross Margin
41%

Actionable Insight

The stock may face downward pressure due to the significant revenue decline and sustained losses. However, traders should monitor the progress of the two new FDA submissions as potential catalysts for future growth. The continued share buyback provides some support, but the weak guidance for Q1 2026 suggests the turnaround will take time.

Key Facts

  • Q4 2025 revenue was $26.8 million, down 29% YoY; full-year revenue was $115 million, down 38% YoY.
  • Core business revenue (excluding COVID-19) declined 22% YoY in Q4 and 14% for the full year.
  • GAAP net loss was $19.3 million for Q4 and $68.7 million for the full year.
  • Company submitted two new applications to the FDA in December 2025 for a rapid molecular self-test for Chlamydia/Gonorrhea and a Colli-Pee at-home urine collection device.
  • Company deployed $5 million to repurchase 1.9 million shares in Q4 and has $25 million remaining on its $40 million buyback program.
  • Q1 2026 revenue guidance is $26-$29 million, indicating no immediate recovery.

Financial Impact

Revenue declined by $10.7 million in Q4 and $70.8 million for the full year, with a net loss of $68.7 million for the year.

revenueepscashFlow

Segment Breakdown

SegmentRevenueGrowth
Core Business$26.7M-22.0%
Diagnostics$15.1M-20.0%
Sample Management Solutions$9.1M-39.0%

Risk Factors

  • Continued revenue decline in core business segments.
  • Failure to gain FDA approval for new product submissions.
  • High operating losses may deplete cash reserves despite strong balance sheet.

Market Snapshot

Exchange
Nasdaq

Documents Analyzed

This report is based on 7 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001116463-26-000009
Exhibit: exhibit992_q4-25investor.htm0001116463-26-000009
Document: osur-20260225.htm0001116463-26-000009
Document: 0001116463-26-000009-index-headers.html0001116463-26-000009
Document: 0001116463-26-000009-index.html0001116463-26-000009
Document: 0001116463-26-000009.txt0001116463-26-000009
CONTEXT: Previous Earnings (2026-02-25)0001116463-26-000009
13 reports for OSUR
Performance horizon
100% Hit rate 6 of 6 directional calls best @ T+60▲ +39.73%Mar 13, 2026
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Jun 12, 2026
today
Institutional Cluster
MIXED ★ 4/10
$4.18 awaiting T+1awaiting T+1$4.18 (+0.12%)
Jun 3, 2026
9d ago
8-K
NEUTRAL ★ 3/10
$4.17 $4.04▼ −3.12%▼ −0.52%$4.18 (+0.24%)
May 6, 2026
5w ago
8-K
BEARISH ★ 6/10
$3.13 $3.06▲ +2.24%▲ +3.07%$4.18 (−33.55%)
Apr 22, 2026
7w ago
Press Release
BEARISH ★ 7/10
$3.05 $3.00▲ +1.64%▲ +2.42%$4.18 (−37.05%)
Apr 17, 2026
8w ago
DEFA14A
BULLISH ★ 7/10
$3.16 $3.19▲ +0.95%▲ +1.14%$4.18 (+32.28%)
Apr 17, 2026
8w ago
DEFA14A
BULLISH ★ 7/10
$3.16 $3.19▲ +0.95%▲ +1.14%$4.18 (+32.28%)
Apr 17, 2026
8w ago
8-K
NEUTRAL ★ 5/10
$3.16 $3.19▲ +0.95%▲ +1.14%$4.18 (+32.28%)
Mar 20, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$2.95 $3.08▲ +4.41%▲ +3.30%$4.18 (+41.69%)
Mar 17, 2026
12w ago
DEFA14A
MIXED ★ 6/10
$2.90 $2.91▲ +0.34%▲ +0.61%$4.18 (+44.14%)
Mar 13, 2026
13w ago
Insider Cluster
BULLISH ★ 6/10
$2.97 $3.13▲ +5.39%▲ +4.36%$4.18 (+40.74%)
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