SYRE Spyre Therapeutics, Inc.

NEUTRAL Impact: 3/10 8-K
Horizon days Filed May 29, 2026 Processed 11d 12h ago SEC 0001636282-26-000056
8-K context-dependent: Items 5.02
Latest settled — T+5d
SYRE ▲ +4.41% at T+5d
NEUTRAL call ✓ call won +4.41% · α vs SPY +7.16% · entry $70.54 → $73.65
Next anchor: T+20d in 19d
Last close $72.00 (close Jun 8) · +2.07% from $70.54 entry
Entry anchored
May 29, 2026
via day open
T+1d
-1.96%
call -1.96% · α -2.10%
$69.16
settled 9d ago
T+5d
+4.41%
call +4.41% · α +7.16%
$73.65
settled 5d ago
T+20d
call — · α —
in 19d
T+60d
call — · α —
in 3mo

Price Chart

Loading chart...

Executive Summary

Spyre Therapeutics held its 2026 Annual Meeting on May 27, 2026, where stockholders approved the amended and restated 2016 Employee Stock Purchase Plan (AR ESPP), adding 1,056,096 shares to the reserve. Director Peter Harwin resigned effective the same date, with no disagreement cited, and the board was reduced from eight to seven members. This is a routine governance filing with no material financial impact.

Actionable Insight

This is a routine post-annual meeting filing with no material trading implications. The ESPP share increase is standard and immaterial relative to market cap. Monitor for any future insider selling patterns following the board resignation, though the departure was explicitly non-disagreement.

Key Facts

  • Stockholders approved the Amended and Restated 2016 Employee Stock Purchase Plan, adding 1,056,096 shares to the reserve.
  • Director Peter Harwin resigned effective May 27, 2026, with no disagreement with the company.
  • Board size reduced from eight to seven directors.
  • All three Class I director nominees (Mark McKenna, Cameron Turtle, Laurie Stelzer) were elected.
  • KPMG LLP was ratified as independent auditor for fiscal year 2026.
  • Say-on-pay proposal received 92.7% support from votes cast (excluding broker non-votes).

Financial Impact

No financial figures reported. The AR ESPP adds 1,056,096 shares to the reserve, representing potential future dilution of approximately 0.7% based on the company's market cap of $6.3B, but no immediate financial impact.

dilution

Risk Factors

  • Potential future dilution from the 1,056,096 ESPP share reserve, though minimal relative to current market cap.
  • Board reduction from eight to seven may concentrate decision-making, but no immediate concern.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
96% bullish (23 analysts)

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001636282-26-000056
Document: syre-20260527.htm0001636282-26-000056
Document: 0001636282-26-000056-index-headers.html0001636282-26-000056
Document: 0001636282-26-000056-index.html0001636282-26-000056
Document: 0001636282-26-000056.txt0001636282-26-000056
16 reports for SYRE
Performance horizon
83% Hit rate 5 of 6 directional calls best @ T+20▲ +20.80%Apr 13, 2026
Filters
Rows
Reports for SYRE — sortable, filterable
Type Now
Jun 4, 2026
6d ago
Insider Cluster
NEUTRAL ★ 2/10
$78.48 $73.65▼ −6.15%▼ −3.56%$72.00 (−8.26%)
Jun 1, 2026
8d ago
8-K
BULLISH ★ 7/10
$69.16 $73.52▲ +6.30%▲ +7.00%$72.00 (+4.11%)
May 29, 2026
11d ago
8-K
NEUTRAL ★ 3/10
$70.54 $69.16▼ −1.96%▼ −2.10%$72.00 (+2.07%)
May 5, 2026
5w ago
8-K
MIXED ★ 6/10
$71.01 $73.00▲ +2.80%▲ +1.42%$72.00 (+1.39%)
May 1, 2026
5w ago
Insider Cluster
NEUTRAL ★ 3/10
$69.42 $69.13▼ −0.42%▼ −0.08%$72.00 (+3.72%)
May 1, 2026
5w ago
Insider Cluster
NEUTRAL ★ 2/10
$69.42 $69.13▼ −0.42%▼ −0.08%$72.00 (+3.72%)
Apr 15, 2026
8w ago
Press Release
NEUTRAL ★ 6/10
$68.99 $69.70▲ +1.03%▲ +0.78%$72.00 (+4.36%)
Apr 13, 2026
8w ago
424B5
BULLISH ★ 8/10
$64.01 $68.99▲ +7.78%▲ +7.01%$72.00 (+12.48%)
Apr 13, 2026
8w ago
Press Release
BEARISH ★ 7/10
$64.01 $68.99▼ −7.78%▼ −7.01%$72.00 (−12.48%)
Apr 13, 2026
8w ago
8-K
NEUTRAL ★ 5/10
$64.01 $68.99▲ +7.78%▲ +7.01%$72.00 (+12.48%)
Showing 10 of 16

US Market Status

Market Closed — Opens in 4h 3m

Subscribe to SecBot

Get Real-Time SEC Filing Intelligence

Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.

Try SecBot Free Coming soon: SecBot Pro with alerts, watchlists, and API access