TWST Twist Bioscience Corp
Price Chart
Executive Summary
A substantial insider selling cluster at Twist Bioscience, concentrated on May 21-26, 2026, with CEO Emily Leproust alone selling ~$3.1M in open-market shares after exercising options. The cluster spans the C-suite (CEO, COO, CFO, Chief Accounting Officer), SVP of HR, and a director. Total open-market sales exceed $3.9M, representing approximately 0.1% of the $4.0B market cap, placing it at the modest-to-notable boundary. The pattern suggests a coordinated response to a single event — likely a planned post-blackout or 10b5-1 window opening following earnings, a press release, or an offering — consistent with the cross-filing amplifications flagged by the actuarial model. While the cluster is broad, the proportionality check to market cap caps the directional read as modest; the strong historical win rate (71% at T+20) and actuarial amplifier for insider-trade clusters at this company support a moderately negative read.
Key Financial Metrics
Actionable Insight
The selling is not economically massive relative to TWST's $4B cap, but the breadth (6 officers + 1 director) and timing (concentrated around a likely corporate catalyst window) are notable. Per the calibration model, cluster insider trades at this company act as an amplifier when paired with earnings, press, offering, or agreement context — suggesting an upcoming material disclosure. Monitor for an 8-K, offering filing, or earnings release in the next 2-4 weeks. A blackout-window opening is the most benign explanation, but the actuarial pattern favors caution.
Key Facts
- CEO Emily Leproust sold 48,034 open-market shares across May 26-27, realizing ~$3.13M in proceeds
- CEO also exercised 74,316 stock options (non-cash and $8.82 strike) over the same period
- Four other C-suite officers (COO, CFO, Chief Accounting Officer, SVP HR) sold shares on May 21, totaling $443K
- A director (Starovasnik) sold $30.5K on May 26 — not in a 10b5-1 pattern
- Total open-market sales in this cluster: ~$3.95M, roughly 0.1% of TWST's $4.0B market cap
- All C-suite sales occurred at prices near $53 (May 21) and $65 (May 26-27), with later sales at higher prices
- No open-market purchases occurred in the cluster — the net direction is unequivocally selling
Financial Impact
Total insider selling of ~$3.95M in open-market sales over one week, representing ~0.1% of market cap
Risk Factors
- Insider cluster selling may indicate upcoming negative news or earnings miss that is not yet public
- CEO sold near $65, near all-time or recent highs for the stock, potentially signaling a belief that shares are fully valued
- Option exercises by CEO created shares that were immediately sold, increasing public float modestly (~74k shares) and increasing tax-related selling pressure
- The lack of any insider buying alongside this cluster confirms uniform bearish positioning among the C-suite
Market Snapshot
Documents Analyzed
This report is based on 1 SEC document filed with EDGAR.
| Document | Accession Number |
|---|---|
| CLUSTER Data (Synthetic) | cluster-TWST-1779998804422 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
|
Jun 2, 2026
3d ago
|
Insider Cluster
| $72.33 $73.93 | ▲ +2.21% | ▲ +1.81% | $69.22 (−4.30%) |
|
Jun 1, 2026
4d ago
|
Insider Cluster
| $70.15 $72.33 | ▲ +3.11% | ▲ +3.80% | $69.22 (−1.33%) |
|
May 28, 2026
8d ago
|
Insider Cluster
| $66.87 $67.86 | ▼ −1.48% | ▼ −1.21% | $69.22 (−3.51%) |
|
May 26, 2026
10d ago
|
Insider Cluster
| $64.17 $69.03 | ▲ +7.57% | ▲ +7.03% | $69.22 (+7.87%) |
|
May 4, 2026
4w ago
|
8-K
| $56.19 $56.70 | ▲ +0.91% | ▲ +0.11% | $69.22 (+23.19%) |
|
Apr 17, 2026
7w ago
|
Insider Cluster
| $59.81 $61.88 | ▲ +3.46% | ▲ +3.65% | $69.22 (+15.73%) |
|
Mar 17, 2026
11w ago
|
Insider Cluster
| $47.28 $44.46 | ▼ −5.96% | ▼ −4.57% | $69.22 (+46.40%) |
|
Mar 6, 2026
13w ago
|
Insider Cluster
| $46.94 $48.33 | ▼ −2.96% | ▼ −2.12% | $69.22 (−47.46%) |
|
Feb 23, 2026
14w ago
|
Insider Cluster
| $48.09 $48.54 | ▼ −0.94% | ▼ −0.20% | $69.22 (−43.94%) |
|
Feb 23, 2026
14w ago
|
Insider Cluster
| $48.09 $48.54 | ▼ −0.94% | ▼ −0.20% | $69.22 (−43.94%) |
US Market Status
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