ZBIO Zenas BioPharma, Inc.

BULLISH Impact: 6/10 Institutional Cluster
Horizon weeks Processed 3mo ago
Institutional cluster: 3 buyers, 0 sellers (bullish)
Final — all horizons settled through T+60d
ZBIO ▼ -26.72% at T+60d
LONG call ✗ call lost -26.72% · α vs SPY -36.05% · entry $25.56 → $18.73
Entry anchored
Feb 27, 03:59 PM ET
via Databento tick
T+1d
-1.49%
call -1.49% · α -0.57%
$25.18
settled 4mo ago
T+5d
+2.27%
call +2.27% · α +3.48%
$26.14
settled 3mo ago
T+20d
-28.70%
call -28.70% · α -20.76%
$18.23
settled 3mo ago
T+60d
-26.72%
call -26.72% · α -36.05%
$18.73
settled 20d ago

Executive Summary

Three major passive institutions — Morgan Stanley, Wells Fargo, and Schwab — significantly increased their positions in Zenas BioPharma during Q4 2024, collectively adding $3.1M in new holdings with no institutional selling observed. This cluster reflects strong institutional accumulation, driven entirely by large passive managers entering or doubling down on positions.

Key Financial Metrics

Direction
accumulating
Buy Value
$3.1M
Net Flow
$3.1M

Institutional Positions

Net institutional flow: $3.1M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
Morgan Stanley DOUBLED +601.7% $2.9M $2.1M
Wells Fargo NEW +0% $65.0K $65.0K
Schwab NEW +0% $972.0K $972.0K

Actionable Insight

While the buyers are passive managers (suggesting index-driven flows rather than active conviction), the scale of new positions — especially Schwab’s $972K entry and Morgan Stanley’s 6x increase — signals growing institutional footprint. Traders should monitor for follow-through buying and potential float concentration, particularly if active managers begin to participate.

Key Facts

  • Morgan Stanley doubled its position, increasing shares from 51.0K to 358.2K (Δ+307.2K) and value from $864K to $2.9M (Δ+$2.1M)
  • Wells Fargo initiated a new position of 8.0K shares worth $65K
  • Schwab initiated a new position of 118.7K shares worth $972K
  • No institutional sellers were identified in this quarter

Financial Impact

3 institutions accumulated $3.1M in net new positions during Q4 2024 with no offsetting sales

float ownershipinstitutional ownershiptrading volume

Risk Factors

  • All buyers are mega-passive institutions, indicating the move may reflect index inclusion or rebalancing rather than fundamental conviction
  • No active or activist funds are participating, limiting the strength of the signal

Market Snapshot

Exchange
Nasdaq

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-ZBIO-2024-Q4
12 reports for ZBIO
Performance horizon
67% Hit rate 2 of 3 directional calls best @ T+5▲ +22.24%Mar 26, 2026
Filters
Rows
Reports for ZBIO — sortable, filterable
Type Now
May 28, 2026
17d ago
Press Release
BULLISH ★ 7/10
$18.56 $18.38▼ −0.97%▼ −1.29%
May 19, 2026
26d ago
Press Release
BULLISH ★ 7/10
$17.84 $18.53▲ +3.84%▲ +1.59%
May 13, 2026
4w ago
Press Release
NEUTRAL ★ 4/10
$19.93 $17.84▼ −10.49%▼ −9.33%
May 13, 2026
4w ago
8-K
NEUTRAL ★ 4/10
$19.93 $17.84▼ −10.49%▼ −9.33%
May 13, 2026
4w ago
Press Release
NEUTRAL ★ 5/10
$19.93 $17.84▼ −10.49%▼ −9.33%
Mar 31, 2026
10w ago
Insider Cluster
MIXED ★ 6/10
$19.55 $20.86▲ +6.70%▲ +2.76%
Mar 27, 2026
11w ago
Press Release
NEUTRAL ★ 6/10
$18.21 $22.26▲ +22.24%▲ +18.38%
Mar 26, 2026
11w ago
424B5
MIXED ★ 6/10
$18.21 $22.26▲ +22.24%▲ +18.38%
Mar 26, 2026
11w ago
424B5
BULLISH ★ 7/10
$18.21 $22.26▲ +22.24%▲ +18.38%
Mar 16, 2026
12w ago
DEFA14A
NEUTRAL ★ 2/10
$23.23 $20.63▼ −11.19%▼ −9.15%
Showing 10 of 12

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