ALXO

ALX ONCOLOGY HOLDINGS INC

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001810182
$1.58 +3.95% $212.6M
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)7 New Institutional Positions
Vol
Market Cap$212.6M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (85%)
Inst. Holders35 funds
Inst. Value$81.0M
Inst. Activity7 buys / 1 sells
Insider Activity1B / 3S
Insider Net $$5.0M
SEC Reports6
Press Releases2
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001810182·Prev Close $1.52

Recent Activity

Jun 12, 2026 SEC
A mixed institutional cluster in ALXO for Q3 2024 shows 6 buyers (net +$124K) and 4 sellers (net -$3.74M), dominated by
INST-CLUSTER — Impact 5/10
May 8, 2026 SEC
ALX Oncology reported Q1 2026 GAAP net loss of ($17.9) million, or ($0.17) per share, narrowing from ($0.58) per share i
8-K — Impact 5/10
May 8, 2026 SEC
ALX Oncology reported Q1 2026 GAAP EPS of -$0.17, significantly missing the consensus estimate of -$0.16 (a -6.25% miss)
PRESS-RELEASE — Impact 6/10
May 8, 2026 earnings
ALX Oncology Reports First Quarter 2026 Financial Results and Provides Corporate Update
<p align="center"><strong><em>- Data from Phase 1b/2 trial of evorpacept + zanidatamab presented at
Apr 16, 2026 Insider
Knight Jeff E. was granted 800,000 shares
Chief Dev & Operating Officer
Apr 16, 2026 Insider
Klencke Barbara was granted 100,000 shares
Chief Medical Officer
Mar 19, 2026 Insider
Lettmann Jason sold 12,311 shares
CHIEF EXECUTIVE OFFICER @ $2.17 ($26.7K)
Inst.
RA CAPITAL MANAGEMENT, L.P. — NEW
13,011,849 shares ($26.1M)

Price Targets

$4.60 +191.1% upside Strong Buy
Current $1.58 Low $4.00 Median $4.00 High $6.00 5 analysts
$4.00 $6.00

Analyst Ratings

Strong Buy85% buy · 13 analysts
3Strong Buy
8Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Mar 19, 2026 Wells Fargo INITIATE Overweight
Mar 10, 2026 HC Wainwright & Co. REITERATE Buy → Buy
Feb 5, 2026 Piper Sandler MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.16 $-0.16 — $-0.16 65% YoY 1
Next Q $-0.16 $-0.16 — $-0.16 1
Current FY $-0.65 $-0.65 — $-0.65 61% YoY 1
Next FY $-0.54 ▲ +12.4% $-0.54 — $-0.54 17% YoY 1

Top Institutional Holders

FundValueMove
RA CAPITAL MANAGEMENT, L.P.$26.1MNEW
Blackstone Inc.$11.7MNEW
DRIEHAUS CAPITAL MANAGEMENT LLC$11.5MDOUBLED
VANGUARD CAPITAL MANAGEMENT LLC$8.4M
MARSHALL WACE, LLP$7.5MDOUBLED

Recent Insider Trades

DateInsiderTypeValue
Apr 16, 2026Knight JeffA$0.00
Apr 16, 2026Klencke BarbaraA$0.00
Mar 19, 2026Lettmann JasonSELL$26.7K
Mar 19, 2026Pinto ShellySELL$2.0K
Mar 3, 2026Klencke BarbaraA$0.00
35 institutional holders with $81.0M total value (40,378,223 shares) as of 2026-Q1. Top holders: RA, Blackstone, DRIEHAUS. Net buying activity: 7 institutions added/increased vs 1 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1RA CAPITAL MANAGEMENT, L.P.13,011,849$26.1M32.2%NEW
2Blackstone Inc.5,826,544$11.7M14.5%NEW
3DRIEHAUS CAPITAL MANAGEMENT LLC5,734,620$11.5M14.2%DOUBLED +303.0%
4VANGUARD CAPITAL MANAGEMENT LLC4,179,736$8.4M10.4%
5MARSHALL WACE, LLP3,757,216$7.5M9.3%DOUBLED +14144.8%
6ADAGE CAPITAL PARTNERS GP, L.L.C.2,000,000$4.0M5.0%
7TWO SIGMA INVESTMENTS, LP1,587,833$3.2M3.9%ADD +26.9%
8SUSQUEHANNA INTERNATIONAL GROUP, LLP1,328,907$2.7M3.3%
9RENAISSANCE TECHNOLOGIES LLC732,599$1.5M1.8%ADD +73.2%
10BANK OF AMERICA CORP /DE/577,783$1.2M1.4%TRIM -48.7%
11BlackRock, Inc.447,799$897.8K1.1%TRIM -37.5%
12VANGUARD FIDUCIARY TRUST CO294,478$590.4K0.7%
13STATE STREET CORP175,828$352.5K0.4%ADD +41.5%
14GOLDMAN SACHS GROUP INC138,593$277.9K0.3%
15MORGAN STANLEY98,835$198.2K0.2%TRIM -27.4%
16VANGUARD PORTFOLIO MANAGEMENT LLC97,881$196.3K0.2%
17Brevan Howard Capital Management LP79,389$159.2K0.2%
18OMERS ADMINISTRATION Corp75,000$150.4K0.2%
19Point72 Asset Management, L.P.41,095$82.4K0.1%DOUBLED +103.3%
20WEALTH ENHANCEMENT ADVISORY SERVICES, LLC37,997$74.9K0.1%ADD +27.9%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
RA CAPITAL MANAGEMENT, L.P.NEW13,011,849$26.1M2026-Q1
Blackstone Inc.NEW5,826,544$11.7M2026-Q1
DRIEHAUS CAPITAL MANAGEMENT LLCDOUBLED1,422,8825,734,620+303.0%$11.5M2026-Q1
MARSHALL WACE, LLPDOUBLED26,3763,757,216+14144.8%$7.5M2026-Q1
RENAISSANCE TECHNOLOGIES LLCADD423,099732,599+73.2%$1.5M2026-Q1
STATE STREET CORPADD124,228175,828+41.5%$352.5K2026-Q1
Point72 Asset Management, L.P.DOUBLED20,21741,095+103.3%$82.4K2026-Q1
CWM, LLCTRIM9665-32.3%$130.002026-Q1
CWM, LLCTRIM14496-33.3%2025-Q4
DRIEHAUS CAPITAL MANAGEMENT LLCADD795,7771,422,882+78.8%$1.6M2025-Q4
RENAISSANCE TECHNOLOGIES LLCDOUBLED164,499423,099+157.2%$478.1K2025-Q4
MARSHALL WACE, LLPTRIM39,58326,376-33.4%$29.8K2025-Q4
COMMONWEALTH EQUITY SERVICES, LLCTRIM20,57215,102-26.6%$17.1K2025-Q4
CWM, LLCNEAR_EXIT1,304144-89.0%2025-Q3
TWO SIGMA INVESTMENTS, LPADD477,934606,671+26.9%$1.1M2025-Q3
BANK OF AMERICA CORP /DE/TRIM1,035,127530,828-48.7%$971.4K2025-Q3
BANK OF MONTREAL /CAN/TRIM668,747474,781-29.0%$868.8K2025-Q3
BlackRock, Inc.TRIM716,297447,692-37.5%$819.3K2025-Q3
UBS Group AGTRIM288,685172,570-40.2%$315.8K2025-Q3
RENAISSANCE TECHNOLOGIES LLCADD85,399164,499+92.6%$301.0K2025-Q3
MORGAN STANLEYTRIM117,46585,290-27.4%$156.1K2025-Q3
MARSHALL WACE, LLPTRIM106,28039,583-62.8%$72.4K2025-Q3
FMR LLCTRIM18,03312,986-28.0%$23.8K2025-Q3
FEDERATED HERMES, INC.TRIM6,5412,374-63.7%$4.3K2025-Q3
PNC FINANCIAL SERVICES GROUP, INC.TRIM397100-74.8%$183.002025-Q3
5 unique insiders with 7 transactions. Net insider value: $5.0M ($5.0M bought, $30.0K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Apr 16, 2026Knight Jeff E.Chief Dev & Operating OfficerAWARD800,000
Apr 16, 2026Klencke BarbaraChief Medical OfficerAWARD100,000
Mar 19, 2026Lettmann JasonCHIEF EXECUTIVE OFFICERSELL12,311$2.17$26.7K
Mar 19, 2026Pinto ShellySVP, FINANCE AND CAOSELL903$2.17$2.0K
Mar 3, 2026Klencke BarbaraChief Medical OfficerAWARD700,000
Feb 18, 2026Pinto ShellySVP, FINANCE AND CAOSELL565$2.27$1.3K
Feb 2, 2026GOODMAN COREY SDirectorBUY3,184,713$1.57$5.0M
Current analyst consensus: Strong Buy (85% buy). Based on 13 analysts: 3 strong buy, 8 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$4.60 mean target +191.1% upside Strong Buy (1.43)
$4.00 Low $6.00 High
MetricValue
Current Price$1.58
Target Low$4.00
Target Mean$4.60
Target Median$4.00
Target High$6.00
# Analysts5
RecommendationStrong Buy (1.43)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.16 $-0.16 $-0.16 64.8% +0.0% $0.0B 0.0% 1
Next Q
2026-09-30
$-0.16 $-0.16 $-0.16 +0.0% $0.0B 0.0% 1
Current FY
2026-12-31
$-0.65 $-0.65 $-0.65 60.8% +0.0% 1↑ 0↓ $0.0B 0.0% 1
Next FY
2027-12-31
$-0.54 $-0.54 $-0.54 17.1% +12.4% 1↑ 0↓ $0.0B 0.0% 1

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.156
7d ago$-0.156
30d ago$-0.156
60d ago$-0.156
90d ago$-0.220+0.064
3 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Mar 19, 2026 Wells Fargo INITIATE Overweight
Mar 10, 2026 HC Wainwright & Co. REITERATE Buy Buy
Feb 5, 2026 Piper Sandler MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20263820085%
May 1, 20263820085%
Apr 1, 20263820085%
Mar 1, 20263620082%
Feb 1, 20263620082%
Jan 1, 20263620082%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 8, 2026
earnings
ALX Oncology Reports First Quarter 2026 Financial Results and Provides Corporate Update
<p align="center"><strong><em>- Data from Phase 1b/2 trial of evorpacept + zanidatamab presented at ESMO Breast Cancer 2026 showed all patients with c
May 8, 2026
earnings_calendar
ALXO Q1 2026 Earnings Scheduled — 2026-05-08
May 7, 2026
fda
ALX Oncology’s Evorpacept in Combination with Zanidatamab Generates Promising, Durable Response in Patients with Advanced HER2-Positive Breast Cancer and High CD47 Expression
<p align="center"><strong><em>- Data from Phase 1b/2 trial presented at ESMO Breast Cancer 2026 further validate a </em></strong><strong><em>biomarker
May 7, 2026
earnings_calendar
ALXO Q1 2026 Earnings Scheduled — 2026-05-07
Apr 17, 2026
other
ALX Oncology Reports Inducement Grant as permitted by the Nasdaq Listing Rules
<p>SOUTH SAN FRANCISCO, Calif., April 17, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. (“ALX Oncology,” Nasdaq: ALXO), a clinical-stage biote
Apr 13, 2026
other
ALX Oncology Appoints Jeff Knight as Chief Development and Operating Officer
<p align="center"><strong><em>- Veteran biopharmaceutical and oncology leader brings more than three decades of experience across clinical development
Apr 7, 2026
short_volume
Short Volume: ALXO — 59.9% short (0.4M / 0.6M)
Short: 357,452 | Exempt: 5,784 | TRF Vol: 597,233 | Short Ratio: 59.9% | Off-exchange volume (dark pool + OTC)
Mar 25, 2026
short_volume
Short Volume: ALXO — 67.4% short (0.4M / 0.5M)
Short: 357,296 | Exempt: 1,609 | TRF Vol: 529,822 | Short Ratio: 67.4% | Off-exchange volume (dark pool + OTC)
Feb 27, 2026
earnings
ALX Oncology Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update
ALX Oncology Q4 and EOY 2025 earnings press release
Feb 27, 2026
earnings_calendar
ALXO Q4 2025 Earnings After Market Close — 2026-02-27