ANNX

Annexon, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001528115
$4.71 +0.21% $771.7M
Insider Selling Cluster (6 insiders)High Impact Filing (7/10)21 New Institutional Positions6 Institutional Exits
Vol
Market Cap$771.7M
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (88%)
Inst. Holders50 funds
Inst. Value$437.9M
Inst. Activity21 buys / 6 sells
Insider Activity4B / 10S
Insider Net $$3.1M
Reddit Sentiment67° Warm
SEC Reports8
Press Releases1
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001528115·Prev Close $4.70

Recent Activity

Jun 12, 2026 SEC
Goldman Sachs initiates ANNX at Neutral — PT $7 (48% upside)
ANALYST-UPGRADE — Impact 2/10
Jun 10, 2026 short_volume
Short Volume: ANNX — 55.1% short (0.6M / 1.1M)
Short: 589,309 | Exempt: 8,373 | TRF Vol: 1,070,159 | Short Ratio: 55.1% | Off-exchange volume (dark
May 28, 2026 Insider
Satter Muneer A bought 613,497 shares
Director @ $5.41 ($3.3M)
May 11, 2026 Insider
Carson William H. bought 8,000 shares
Director @ $5.78 ($46.2K)
Apr 16, 2026 SEC
Clear Street initiates coverage on ANNX with a Buy rating and $17 price target, implying 193% upside from the current $5
ANALYST-UPGRADE — Impact 8/10
Apr 16, 2026 SEC
Chardan Capital initiates coverage on ANNX with a Buy rating and $16 price target, implying 176% upside from the current
ANALYST-UPGRADE — Impact 7/10
Apr 10, 2026 Insider
Carson William H. bought 8,000 shares
Director @ $6.20 ($49.6K)
Inst.
STATE STREET CORP — ADD
6,919,255 shares ($38.3M)

Price Targets

$13.13 +178.7% upside Strong Buy
Current $4.71 Low $7.00 Median $11.50 High $27.00 8 analysts
$7.00 $27.00

Analyst Ratings

Strong Buy88% buy · 17 analysts
4Strong Buy
11Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 12, 2026 Goldman Sachs INITIATE Neutral
Mar 20, 2026 Chardan Capital MAINTAIN Buy → Buy
Dec 23, 2025 Chardan Capital INITIATE Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.24 ▲ +20.6% $-0.27 — $-0.22 29% YoY 6
Next Q $-0.25 ▲ +11.1% $-0.30 — $-0.21 32% YoY 6
Current FY $-0.98 ▲ +15.5% $-1.14 — $-0.86 27% YoY 6
Next FY $-0.92 ▲ +3.5% $-1.28 — $-0.64 6% YoY 6

Top Institutional Holders

FundValueMove
BlackRock, Inc.$60.6M
FMR LLC$58.9MTRIM
STATE STREET CORP$38.3MADD
VANGUARD CAPITAL MANAGEMENT LLC$33.0M
ADAGE CAPITAL PARTNERS GP,$23.8MDOUBLED

Recent Insider Trades

DateInsiderTypeValue
May 28, 2026Satter MuneerBUY$3.3M
May 11, 2026Carson WilliamBUY$46.2K
Apr 10, 2026Carson WilliamBUY$49.6K
Mar 10, 2026Carson WilliamBUY$45.4K
Mar 2, 2026ARTIS DEANSELL$32.0K

Reddit Sentiment

67°
Warm
Bearish Neutral Bullish
2 mentions 2 bullish 0 bearish
50 institutional holders with $437.9M total value (79,054,211 shares) as of 2026-Q1. Top holders: BlackRock,, FMR, STATE. Net buying activity: 21 institutions added/increased vs 6 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1BlackRock, Inc.10,938,509$60.6M13.8%
2FMR LLC10,635,648$58.9M13.5%TRIM -29.4%
3STATE STREET CORP6,919,255$38.3M8.8%ADD +48.7%
4VANGUARD CAPITAL MANAGEMENT LLC5,956,589$33.0M7.5%
5ADAGE CAPITAL PARTNERS GP, L.L.C.4,300,000$23.8M5.4%DOUBLED +266.7%
6BANK OF AMERICA CORP /DE/4,259,995$23.6M5.4%DOUBLED +165.3%
7Nuveen, LLC4,246,330$23.5M5.4%ADD +45.7%
8BALYASNY ASSET MANAGEMENT L.P.3,886,909$21.5M4.9%DOUBLED +154.3%
9AMERIPRISE FINANCIAL INC3,449,121$19.1M4.4%ADD +98.4%
10MORGAN STANLEY2,735,970$15.2M3.5%DOUBLED +263.9%
11Woodline Partners LP2,337,137$12.9M3.0%TRIM -41.6%
12GOLDMAN SACHS GROUP INC2,152,880$11.9M2.7%
13Point72 Asset Management, L.P.1,871,795$10.4M2.4%DOUBLED +404.3%
14VANGUARD PORTFOLIO MANAGEMENT LLC1,483,090$8.2M1.9%
15CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,102,445$6.1M1.4%ADD +33.8%
16DIMENSIONAL FUND ADVISORS LP924,078$5.1M1.2%ADD +28.6%
17MASSACHUSETTS FINANCIAL SERVICES CO /MA/903,368$5.0M1.1%
18VANGUARD FIDUCIARY TRUST CO888,552$4.9M1.1%
19MARSHALL WACE, LLP861,475$4.8M1.1%ADD +65.4%
20Invesco Ltd.763,005$4.2M1.0%DOUBLED +381.5%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
STATE STREET CORPADD4,652,1856,919,255+48.7%$38.3M2026-Q1
BANK OF AMERICA CORP /DE/DOUBLED1,605,5814,259,995+165.3%$23.6M2026-Q1
Nuveen, LLCADD2,915,3244,246,330+45.7%$23.5M2026-Q1
Woodline Partners LPTRIM4,000,0742,337,137-41.6%$12.9M2026-Q1
Point72 Asset Management, L.P.DOUBLED371,1901,871,795+404.3%$10.4M2026-Q1
DIMENSIONAL FUND ADVISORS LPADD718,680924,078+28.6%$5.1M2026-Q1
MARSHALL WACE, LLPADD520,998861,475+65.4%$4.8M2026-Q1
RENAISSANCE TECHNOLOGIES LLCTRIM802,600544,300-32.2%$3.0M2026-Q1
WELLINGTON MANAGEMENT GROUP LLPADD398,077521,379+31.0%$2.9M2026-Q1
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCTRIM642,038416,698-35.1%$2.3M2026-Q1
Rafferty Asset Management, LLCADD141,644203,269+43.5%$1.1M2026-Q1
SEI INVESTMENTS CODOUBLED58,259203,236+248.8%$1.1M2026-Q1
RHUMBLINE ADVISERSADD126,463159,670+26.3%$884.6K2026-Q1
VICTORY CAPITAL MANAGEMENT INCDOUBLED14,757115,527+682.9%$640.0K2026-Q1
DnB Asset Management ASTRIM118,32488,617-25.1%$490.9K2026-Q1
Legal & General Group PlcDOUBLED9,30780,046+760.1%$443.5K2026-Q1
CAPTRUST FINANCIAL ADVISORSDOUBLED31,58579,173+150.7%$438.6K2026-Q1
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.ADD54,76376,257+39.2%$414.1K2026-Q1
MetLife Investment Management, LLCADD39,05972,444+85.5%$401.3K2026-Q1
Brevan Howard Capital Management LPTRIM123,75358,433-52.8%$323.7K2026-Q1
Mariner, LLCADD31,33553,242+69.9%$294.8K2026-Q1
CANADA PENSION PLAN INVESTMENT BOARDDOUBLED17,60040,800+131.8%$226.0K2026-Q1
CWM, LLCADD30,29739,652+30.9%$219.7K2026-Q1
TD ASSET MANAGEMENT INCTRIM46,84822,760-51.4%$126.1K2026-Q1
NISA INVESTMENT ADVISORS, LLCDOUBLED2,6137,413+183.7%$41.1K2026-Q1
8 unique insiders with 25 transactions. Net insider value: $3.1M ($3.5M bought, $313.4K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 28, 2026Satter Muneer ADirectorBUY613,497$5.41$3.3M
May 11, 2026Carson William H.DirectorBUY8,000$5.78$46.2K
Apr 10, 2026Carson William H.DirectorBUY8,000$6.20$49.6K
Mar 10, 2026Carson William H.DirectorBUY8,000$5.67$45.4K
Mar 2, 2026ARTIS DEAN RICHARDEVP & CHIEF SCIENTIFIC OFFICERSELL5,894$5.43$32.0K
Mar 2, 2026Dananberg JamieCHIEF MEDICAL OFFICERSELL5,820$5.43$31.6K
Mar 2, 2026Lew JenniferEVP & CHIEF FINANCIAL OFFICERSELL5,565$5.42$30.2K
Mar 2, 2026Overdorf MichaelEVP & CHIEF BUSINESS OFFICERSELL4,339$5.42$23.5K
Mar 2, 2026Yednock TedEVP & CHIEF INNOVATION OFFICERSELL5,566$5.42$30.2K
Feb 19, 2026Yednock TedEVP & CHIEF INNOVATION OFFICERAWARD62,500
Feb 19, 2026Yednock TedEVP & CHIEF INNOVATION OFFICERAWARD250,000
Feb 19, 2026Love DouglasPRESIDENT AND CEOAWARD1,250,000
Feb 19, 2026Dananberg JamieCHIEF MEDICAL OFFICERAWARD56,250
Feb 19, 2026Dananberg JamieCHIEF MEDICAL OFFICERAWARD225,000
Feb 19, 2026Overdorf MichaelEVP & CHIEF BUSINESS OFFICERAWARD62,500
Feb 19, 2026Overdorf MichaelEVP & CHIEF BUSINESS OFFICERAWARD250,000
Feb 19, 2026ARTIS DEAN RICHARDEVP & CHIEF SCIENTIFIC OFFICERAWARD62,500
Feb 19, 2026ARTIS DEAN RICHARDEVP & CHIEF SCIENTIFIC OFFICERAWARD250,000
Feb 19, 2026Lew JenniferEVP & CHIEF FINANCIAL OFFICERAWARD62,500
Feb 19, 2026Lew JenniferEVP & CHIEF FINANCIAL OFFICERAWARD250,000
Feb 18, 2026Lew JenniferEVP & CHIEF FINANCIAL OFFICERSELL7,851$5.11$40.1K
Feb 18, 2026Dananberg JamieCHIEF MEDICAL OFFICERSELL5,290$5.10$27.0K
Feb 18, 2026Yednock TedEVP & CHIEF INNOVATION OFFICERSELL7,857$5.11$40.1K
Feb 18, 2026Overdorf MichaelEVP & CHIEF BUSINESS OFFICERSELL6,225$5.10$31.7K
Feb 18, 2026ARTIS DEAN RICHARDEVP & CHIEF SCIENTIFIC OFFICERSELL5,290$5.10$27.0K
Current analyst consensus: Strong Buy (88% buy). Based on 17 analysts: 4 strong buy, 11 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$13.13 mean target +178.7% upside Strong Buy (1.40)
$7.00 Low $27.00 High
MetricValue
Current Price$4.71
Target Low$7.00
Target Mean$13.13
Target Median$11.50
Target High$27.00
# Analysts8
RecommendationStrong Buy (1.40)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.24 $-0.27 $-0.22 29.5% +20.6% 4↑ 0↓ $0.0B 0.0% 6
Next Q
2026-09-30
$-0.25 $-0.30 $-0.21 31.9% +11.1% 4↑ 0↓ $0.0B 0.0% 6
Current FY
2026-12-31
$-0.98 $-1.14 $-0.86 26.7% +15.5% 4↑ 0↓ $0.0B 0.0% 6
Next FY
2027-12-31
$-0.92 $-1.28 $-0.64 6.0% +3.5% 3↑ 1↓ $0.0B 0.0% 6

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.240
7d ago$-0.237-0.002
30d ago$-0.302+0.062
60d ago$-0.337+0.097
90d ago$-0.337+0.097
2 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 2 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 12, 2026 Goldman Sachs INITIATE Neutral
Mar 20, 2026 Chardan Capital MAINTAIN Buy Buy
Dec 23, 2025 Chardan Capital INITIATE Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202641120088%
May 1, 202641110094%
Apr 1, 202641110094%
Mar 1, 202641110094%
Feb 1, 202641110094%
Jan 1, 202641110094%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

67°
Warm
Bearish Neutral Bullish
2 mentions 2 bullish 0 bearish 2 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Apr 25, 2026160° Warm101
Apr 25, 2026160° Warm101
Jun 10, 2026
short_volume
Short Volume: ANNX — 55.1% short (0.6M / 1.1M)
Short: 589,309 | Exempt: 8,373 | TRF Vol: 1,070,159 | Short Ratio: 55.1% | Off-exchange volume (dark pool + OTC)
Jun 5, 2026
short_volume
Short Volume: ANNX — 66.9% short (0.4M / 0.7M)
Short: 442,181 | Exempt: 0 | TRF Vol: 661,225 | Short Ratio: 66.9% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: ANNX — 57.4% short (0.5M / 0.8M)
Short: 475,414 | Exempt: 52 | TRF Vol: 827,886 | Short Ratio: 57.4% | Off-exchange volume (dark pool + OTC)
May 29, 2026
short_volume
Short Volume: ANNX — 56.8% short (0.4M / 0.7M)
Short: 411,892 | Exempt: 0 | TRF Vol: 725,184 | Short Ratio: 56.8% | Off-exchange volume (dark pool + OTC)
May 26, 2026
short_volume
Short Volume: ANNX — 94.0% short (3.3M / 3.5M)
Short: 3,326,317 | Exempt: 0 | TRF Vol: 3,539,125 | Short Ratio: 94.0% | Off-exchange volume (dark pool + OTC)
May 18, 2026
other
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">BRISBANE, Calif., May 18, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next g
May 18, 2026
earnings_calendar
ANNX Q1 2026 Earnings Scheduled — 2026-05-18
May 18, 2026
short_volume
Short Volume: ANNX — 77.6% short (1.0M / 1.3M)
Short: 1,012,793 | Exempt: 9 | TRF Vol: 1,304,950 | Short Ratio: 77.6% | Off-exchange volume (dark pool + OTC)
May 15, 2026
short_volume
Short Volume: ANNX — 73.6% short (0.4M / 0.5M)
Short: 395,249 | Exempt: 15 | TRF Vol: 537,142 | Short Ratio: 73.6% | Off-exchange volume (dark pool + OTC)
May 13, 2026
short_volume
Short Volume: ANNX — 59.0% short (0.3M / 0.6M)
Short: 343,018 | Exempt: 0 | TRF Vol: 581,057 | Short Ratio: 59.0% | Off-exchange volume (dark pool + OTC)
May 11, 2026
earnings_calendar
ANNX Q1 2026 Earnings Scheduled — 2026-05-11
May 7, 2026
earnings
Annexon Reports First Quarter 2026 Financial Results, Portfolio Progress and Key Anticipated Milestones
<p align="center"><em>Topline Pivotal Phase 3 Data for Vonaprument for the Treatment of Geographic Atrophy (GA) Expected Q4 2026, with Potential to Re
May 7, 2026
short_volume
Short Volume: ANNX — 56.2% short (0.4M / 0.7M)
Short: 408,824 | Exempt: 4,000 | TRF Vol: 726,869 | Short Ratio: 56.2% | Off-exchange volume (dark pool + OTC)
May 6, 2026
other
Annexon to Present at the Bank of America Securities Health Care Conference 2026
<p>BRISBANE, Calif., May 06, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platfo
Apr 30, 2026
short_volume
Short Volume: ANNX — 59.2% short (0.4M / 0.6M)
Short: 364,081 | Exempt: 0 | TRF Vol: 614,744 | Short Ratio: 59.2% | Off-exchange volume (dark pool + OTC)