ASND

Ascendis Pharma A/S

Nasdaq · Pharmaceutical Preparations · Inc. G7 · CIK 0001612042
$218.06 +1.14% $13.5B
Insider Buying Cluster (2 insiders)High Impact Filing (9/10)13 New Institutional Positions18 Institutional Exits
Vol
Market Cap$13.5B
Cap SizeLarge Cap
Analyst ConsensusStrong Buy (96%)
Inst. Holders50 funds
Inst. Value$9.1B
Inst. Activity13 buys / 18 sells
Insider Activity4B / 1S
Insider Net $-$4.5M
SEC Reports12
Press Releases4
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. G7·CIK 0001612042·Prev Close $215.60

Recent Activity

Jun 13, 2026 Press
Ascendis Pharma announced sustained efficacy and safety data from the Phase 3 PaTHway Trial of TransCon PTH (YORVIPATH)
Impact 7/10
Jun 13, 2026 fda
Phase 3 Data Show TransCon® PTH Replicated Systemic Actions of Endogenous PTH Through Week 182 in Adults with Hypoparathyroidism
<p>COPENHAGEN, Denmark, June 13, 2026 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today
Jun 5, 2026 Event
Ibuprofen
Cardiovascular Thrombotic Events Non-steroidal anti-inflammatory drugs (NSAIDs) cause an increased r
Jun 2, 2026 Insider
SMITH SCOTT THOMAS bought 100 shares
EVP & Chief Financial Officer @ $219.00 ($21.9K)
May 29, 2026 Insider
SMITH SCOTT THOMAS bought 250 shares
EVP & Chief Financial Officer @ $223.32 ($55.8K)
May 29, 2026 Insider
BIENAIME JEAN JACQUES bought 200 shares
Director @ $223.76 ($44.8K)
May 19, 2026 SEC
Citigroup initiates ASND to Buy — PT $355 (+44.7%)
ANALYST-UPGRADE — Impact 3/10
May 16, 2026 SEC
Morgan Stanley upgrades ASND to Overweight — PT $250 (+1.8% from current, +38.9% from prior)
ANALYST-UPGRADE — Impact 3/10

Price Targets

$298.27 +36.8% upside Strong Buy
Current $218.06 Low $252.58 Median $295.48 High $354.22 17 analysts
$252.58 $354.22

Analyst Ratings

Strong Buy96% buy · 26 analysts
12Strong Buy
13Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 19, 2026 Citigroup INITIATE Buy
May 15, 2026 Evercore ISI Group MAINTAIN Outperform → Outperform
May 11, 2026 Barclays MAINTAIN Overweight → Overweight
May 8, 2026 Wells Fargo MAINTAIN Overweight → Overweight
Apr 16, 2026 B of A Securities MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $0.70 ▲ +34.3% $0.44 — $1.06 6
Next Q $1.15 ▲ +15.7% $0.50 — $1.63 6
Current FY $11.44 ▲ +305.8% $2.13 — $16.69 8
Next FY $9.42 ▲ +23.3% $7.56 — $11.70 -18% YoY 8

Top Institutional Holders

FundValueMove
RA CAPITAL MANAGEMENT, L.P.$2.4B
Avoro Capital Advisors LLC$1.2B
FMR LLC$886.7M
Artisan Partners Limited Partnership$738.8M
FRANKLIN RESOURCES INC$469.3M

Recent Insider Trades

DateInsiderTypeValue
Jun 2, 2026SMITH SCOTTBUY$21.9K
May 29, 2026SMITH SCOTTBUY$55.8K
May 29, 2026BIENAIME JEANBUY$44.8K
May 26, 2026BIENAIME JEANBUY$47.2K
May 11, 2026JENSEN FLEMMINGSELL$4.6M
50 institutional holders with $9.1B total value (39,722,428 shares) as of 2026-Q1. Top holders: RA, Avoro, FMR. Net selling activity: 18 institutions trimmed/exited vs 13 added.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1RA CAPITAL MANAGEMENT, L.P.10,281,496$2.4B25.9%
2Avoro Capital Advisors LLC5,062,500$1.2B12.8%
3FMR LLC3,876,601$886.7M9.8%
4Artisan Partners Limited Partnership3,230,188$738.8M8.1%
5FRANKLIN RESOURCES INC2,051,948$469.3M5.2%
6Capital International Investors1,958,843$448.0M4.9%TRIM -36.1%
7MASSACHUSETTS FINANCIAL SERVICES CO /MA/1,860,669$425.6M4.7%
8WELLINGTON MANAGEMENT GROUP LLP1,757,633$402.0M4.4%
9Capital World Investors900,517$206.0M2.3%NEW
10BlackRock, Inc.661,054$151.2M1.7%ADD +39.1%
11Polar Capital Holdings Plc651,712$149.1M1.6%ADD +75.9%
12MORGAN STANLEY606,348$138.7M1.5%ADD +51.9%
13GOLDMAN SACHS GROUP INC566,192$129.5M1.4%
14NOMURA ASSET MANAGEMENT INTERNATIONAL INC.556,427$127.3M1.4%
15AMERIPRISE FINANCIAL INC476,466$109.0M1.2%
16FIL Ltd447,421$102.3M1.1%
17AMERIPRISE FINANCIAL INC411,500$94.1M1.0%
18Invesco Ltd.362,109$82.8M0.9%TRIM -38.2%
19SEI INVESTMENTS CO351,146$80.3M0.9%ADD +37.1%
20SUSQUEHANNA INTERNATIONAL GROUP, LLP305,500$69.9M0.8%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
Capital International InvestorsTRIM3,063,9431,958,843-36.1%$448.0M2026-Q1
Capital World InvestorsNEW900,517$206.0M2026-Q1
Polar Capital Holdings PlcADD370,473651,712+75.9%$149.1M2026-Q1
Invesco Ltd.TRIM586,094362,109-38.2%$82.8M2026-Q1
Pictet Asset Management Holding SADOUBLED73,418251,833+243.0%$56.9M2026-Q1
DEUTSCHE BANK AG\TRIM296,818135,187-54.5%$30.9M2026-Q1
RENAISSANCE TECHNOLOGIES LLCNEW117,332$26.8M2026-Q1
VOLORIDGE INVESTMENT MANAGEMENT, LLCTRIM216,173114,275-47.1%$26.1M2026-Q1
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPNEW91,470$20.9M2026-Q1
STATE STREET CORPADD67,94987,334+28.5%$20.0M2026-Q1
LOOMIS SAYLES & CO L PTRIM112,24080,405-28.4%$18.4M2026-Q1
NATIONAL BANK OF CANADA /FI/NEW80,017$18.3M2026-Q1
FIRST TRUST ADVISORS LPDOUBLED12,23031,135+154.6%$7.1M2026-Q1
VICTORY CAPITAL MANAGEMENT INCTRIM43,19030,770-28.8%$7.0M2026-Q1
CANADA PENSION PLAN INVESTMENT BOARDTRIM71,51630,663-57.1%$7.0M2026-Q1
Brevan Howard Capital Management LPTRIM48,26026,200-45.7%$6.0M2026-Q1
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am MainTRIM48,09723,997-50.1%$5.5M2026-Q1
Jain Global LLCNEAR_EXIT216,52617,207-92.1%$3.9M2026-Q1
Erste Asset Management GmbHTRIM20,30011,200-44.8%$2.4M2026-Q1
Nuveen, LLCTRIM9,0986,051-33.5%$1.4M2026-Q1
DnB Asset Management ASTRIM5,9773,514-41.2%$803.8K2026-Q1
Vident Advisory, LLCADD1,9262,498+29.7%$571.4K2026-Q1
Daiwa Securities Group Inc.TRIM3,1042,269-26.9%$519.0K2026-Q1
POLEN CAPITAL MANAGEMENT LLCADD1,2111,812+49.6%$414.5K2026-Q1
Allworth Financial LPDOUBLED11118+972.7%$27.0K2026-Q1
3 unique insiders with 5 transactions. Net insider value: -$4.5M ($169.7K bought, $4.6M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 2, 2026SMITH SCOTT THOMASEVP & Chief Financial OfficerBUY100$219.00$21.9K
May 29, 2026SMITH SCOTT THOMASEVP & Chief Financial OfficerBUY250$223.32$55.8K
May 29, 2026BIENAIME JEAN JACQUESDirectorBUY200$223.76$44.8K
May 26, 2026BIENAIME JEAN JACQUESDirectorBUY200$236.24$47.2K
May 11, 2026JENSEN FLEMMING STEENSee RemarksSELL19,460$238.49$4.6M
12 SEC filing reports analyzed. Sentiment: 9 bullish, 0 bearish, 0 mixed, 3 neutral. Avg impact: 5.6/10.
BULLISH ANALYST-UPGRADE 3/10
Citigroup initiates ASND to Buy — PT $355 (+44.7%)
May 19, 2026
BULLISH ANALYST-UPGRADE 9/10
Morgan Stanley upgraded ASND from Equal-Weight to Overweight with a $250 price target, up from $180,
Apr 16, 2026
BULLISH ANALYST-UPGRADE 3/10
Morgan Stanley upgrades ASND to Overweight — PT $250 (+1.8% from current, +38.9% from prior)
May 16, 2026
BULLISH 6-K 7/10
Ascendis Pharma announced 5-year (Week 266) data from its Phase 2 PaTH Forward Trial for TransCon PT
Jun 12, 2026
BULLISH CLUSTER 4/10
CFO Scott Thomas and Director Jean-Jacques Bienaimé made open-market purchases totaling $67K over a
Jun 2, 2026
BULLISH 6-K 8/10
Ascendis Pharma reported Q1 2026 revenue of €247M (up 144% YoY from €101M), driven by YORVIPATH sale
May 7, 2026
BULLISH 6-K 7/10
Ascendis Pharma reported Q1 2026 revenue of €246.6M (+144% YoY), driven by YORVIPATH sales tripling
May 7, 2026
NEUTRAL 6-K 3/10
Ascendis Pharma A/S updated the International Securities Identification Number (ISIN) for its ordina
Apr 21, 2026
NEUTRAL 6-K 5/10
Ascendis Pharma A/S announced a transition to a direct listing of its ordinary shares on Nasdaq, rep
Apr 8, 2026
BULLISH 6-K 8/10
Ascendis Pharma released new Week 52 data from its Phase 2 COACH trial showing that TransCon CNP and
Apr 8, 2026
BULLISH 6-K 8/10
Ascendis Pharma announced that YUVIWEL (navepegritide), its once-weekly treatment for children with
Apr 7, 2026
NEUTRAL 3 2/10
Jean-Jacques Bienaime, a director or significant insider of Ascendis Pharma, filed a Form 3 to repor
Apr 1, 2026
Current analyst consensus: Strong Buy (96% buy). Based on 26 analysts: 12 strong buy, 13 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$298.27 mean target +36.8% upside Strong Buy (1.24)
$252.58 Low $354.22 High
MetricValue
Current Price$218.06
Target Low$252.58
Target Mean$298.27
Target Median$295.48
Target High$354.22
# Analysts17
RecommendationStrong Buy (1.24)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$0.70 $0.44 $1.06 +34.3% $0.3B 110.0% 6
Next Q
2026-09-30
$1.15 $0.50 $1.63 +15.7% $0.4B 65.7% 6
Current FY
2026-12-31
$11.44 $2.13 $16.69 +305.8% $1.3B 85.8% 8
Next FY
2027-12-31
$9.42 $7.56 $11.70 -17.6% +23.3% $1.9B 45.2% 8

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$0.702
7d ago$0.702
30d ago$0.522+0.179
60d ago$0.000+0.702
90d ago$0.000+0.702
9 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 2 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 19, 2026 Citigroup INITIATE Buy
May 15, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
May 11, 2026 Barclays MAINTAIN Overweight Overweight
May 8, 2026 Wells Fargo MAINTAIN Overweight Overweight
Apr 16, 2026 B of A Securities MAINTAIN Buy Buy
Apr 9, 2026 Wedbush REITERATE Outperform Outperform
Mar 3, 2026 RBC Capital MAINTAIN Outperform Outperform
Feb 12, 2026 Oppenheimer MAINTAIN Outperform Outperform
Feb 12, 2026 Wedbush MAINTAIN Outperform Outperform
Jan 30, 2026 B of A Securities MAINTAIN Buy Buy
Jan 28, 2026 Barclays INITIATE Overweight
Jan 20, 2026 RBC Capital MAINTAIN Outperform Outperform
Jan 20, 2026 Wells Fargo MAINTAIN Overweight Overweight
Jan 9, 2026 Wells Fargo MAINTAIN Overweight Overweight
Jan 7, 2026 TD Cowen REITERATE Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 2026121310096%
May 1, 2026111210096%
Apr 1, 2026111210096%
Mar 1, 2026111210096%
Feb 1, 2026111210096%
Jan 1, 2026111110096%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 13, 2026
fda
Phase 3 Data Show TransCon® PTH Replicated Systemic Actions of Endogenous PTH Through Week 182 in Adults with Hypoparathyroidism
<p>COPENHAGEN, Denmark, June 13, 2026 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced Week 182 data from its completed Phase
Jun 11, 2026
other
5-Year Phase 2 Data Show TransCon® PTH Replicated Systemic Actions of Endogenous PTH in Adults with Hypoparathyroidism
<p align="center"><em>– Multi-organ system and quality-of-life benefits sustained through five years of treatment</em></p>
Jun 8, 2026
routine
Ascendis to Showcase Advances in Treatment of Rare Endocrine Diseases at ENDO 2026
<p align="left">COPENHAGEN, Denmark, June 08, 2026 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced that the latest data from
Jun 5, 2026
FDA
Ibuprofen
Cardiovascular Thrombotic Events Non-steroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, i
Jun 1, 2026
FDA
CLOPIDOGREL
WARNING: DIMINISHED ANTIPLATELET EFFECT IN PATIENTS WITH TWO LOSS-OF-FUNCTION ALLELES OF THE CYP2C19 GENE The effectiveness of clopidogrel tablets res
Jun 1, 2026
FDA
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE
WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue olmesartan medoxomil and hydrochlorothiazide tablet as soon as possible [see Warning
May 29, 2026
FDA
EstroGel
WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, PROBABLE DEMENTIA and BREAST CANCER Estrogen-Alone Therapy Endometrial Cancer There is an incre
May 27, 2026
FDA
Mycophenolate mofetil
WARNING: EMBRYOFETAL TOXICITY, MALIGNANCIES and SERIOUS INFECTIONS Use during pregnancy is associated with increased risks of first trimester pregnanc
May 13, 2026
Clinical Trial
A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors
Phase Phase 2 — TERMINATED
May 13, 2026
short_interest
FTD: ASND — 9,023 shares ($2.1M) failed to deliver
Settlement: 20260513, Price: $237.65, FTD Value: $2,144,315.95, ASCENDIS PHARMA A/S SHS USD (D
May 7, 2026
earnings
Ascendis Pharma Reports First Quarter 2026 Financial Results
<p align="center"><em>- Q1 2026 revenue of €197 million for YORVIPATH</em><sup>®</sup> <em>and €44 million for SKYTROFA</em><sup>®</sup></p>
May 6, 2026
fda
New 2-Year Data from Pivotal ApproaCH Trial of TransCon® CNP (Navepegritide) Show Pronounced Gains in Growth Outcomes in Children with Achondroplasia Aged ≥5 Years
<p align="left">COPENHAGEN, Denmark, May 06, 2026 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced new data from a subgroup an
May 6, 2026
short_interest
FTD: ASND — 16,215 shares ($3.7M) failed to deliver
Settlement: 20260506, Price: $225.28, FTD Value: $3,652,915.2, ASCENDIS PHARMA A/S SHS USD (D
May 5, 2026
short_interest
FTD: ASND — 16,175 shares ($3.7M) failed to deliver
Settlement: 20260505, Price: $228.71, FTD Value: $3,699,384.25, ASCENDIS PHARMA A/S SHS USD (D
May 4, 2026
short_interest
FTD: ASND — 14,338 shares ($3.2M) failed to deliver
Settlement: 20260504, Price: $220.93, FTD Value: $3,167,694.34, ASCENDIS PHARMA A/S SHS USD (D
May 1, 2026
short_interest
FTD: ASND — 3,615 shares ($0.8M) failed to deliver
Settlement: 20260501, Price: $229.38, FTD Value: $829,208.7, ASCENDIS PHARMA A/S SHS USD (D
Apr 30, 2026
short_interest
FTD: ASND — 5,558 shares ($1.2M) failed to deliver
Settlement: 20260430, Price: $220.28, FTD Value: $1,224,316.24, ASCENDIS PHARMA A/S SHS USD (D
Apr 29, 2026
short_volume
Short Volume: ASND — 91.5% short (1.2M / 1.3M)
Short: 1,215,379 | Exempt: 15 | TRF Vol: 1,328,007 | Short Ratio: 91.5% | Off-exchange volume (dark pool + OTC)
Apr 29, 2026
earnings_calendar
ASND Q1 2026 Earnings After Market Close — 2026-04-29
Apr 28, 2026
short_interest
FTD: ASND — 34,042 shares ($7.7M) failed to deliver
Settlement: 20260428, Price: $226.66, FTD Value: $7,715,959.72, ASCENDIS PHARMA A/S SHS USD (D
Apr 28, 2026
short_volume
Short Volume: ASND — 69.5% short (1.2M / 1.7M)
Short: 1,187,135 | Exempt: 92,714 | TRF Vol: 1,707,448 | Short Ratio: 69.5% | Off-exchange volume (dark pool + OTC)