CCCC

C4 Therapeutics, Inc.

Nasdaq · Biological Products, (No Diagnostic Substances) · Inc. DE · CIK 0001662579
$3.90 +0.78% $431.2M
High Impact Filing (7/10)6 New Institutional Positions4 Institutional Exits
Vol
Market Cap$431.2M
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (93%)
Inst. Holders50 funds
Inst. Value$124.3M
Inst. Activity6 buys / 4 sells
SEC Reports6
Press Releases3
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·Inc. DE·CIK 0001662579·Prev Close $3.87

Recent Activity

Jun 11, 2026 Press
C4 Therapeutics presented updated Phase 1 data for cemsidomide at EHA 2026, showing a 53% overall response rate at the 1
Impact 6/10
Jun 11, 2026 fda
C4 Therapeutics Presents Phase 1 Data at European Hematology Association (EHA) 2026 Congress Highlighting Cemsidomide as a Potential Best-in-Class IKZF1/3 Degrader for Multiple Myeloma in Heavily Pretreated Relapsed/Refractory Population
<p align="center"><em>At the 100 µg Recommended Phase 2 Dose (RP2D), Cemsidomide Demonstrated a 53%
Jun 1, 2026 Insider
Anderson Kenneth Carl acquired via exercise 1,070 shares
Director @ $2.11 ($2.3K)
May 15, 2026 SEC
C4 Therapeutics disclosed the departure of Chief Accounting Officer Mark Mossler, effective May 15, 2026, with no disagr
8-K — Impact 2/10
May 12, 2026 SEC
C4 Therapeutics reported Q1 2026 revenue of $6.2M (down 14% YoY from $7.2M) and a net loss per share of -$0.20 (improved
8-K — Impact 4/10
May 12, 2026 SEC
C4 Therapeutics reported Q1 2026 results with an EPS beat ($-0.18 vs $-0.26 consensus) and revenue beat ($6.2M vs $4.4M
PRESS-RELEASE — Impact 5/10
Apr 1, 2026 Insider
Anderson Kenneth Carl was granted 4,259 shares
Director @ $2.70 ($11.5K)
Apr 1, 2026 Insider
GROGAN DONNA ROY was granted 5,370 shares
Director @ $2.70 ($14.5K)

Price Targets

$13.33 +241.9% upside Strong Buy
Current $3.90 Low $7.00 Median $11.00 High $30.00 6 analysts
$7.00 $30.00

Analyst Ratings

Strong Buy93% buy · 14 analysts
5Strong Buy
8Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Jun 1, 2026 Evercore ISI Group MAINTAIN Outperform → Outperform
Feb 27, 2026 Barclays MAINTAIN Overweight → Overweight
Feb 23, 2026 Brookline Capital MAINTAIN Buy → Buy
Dec 17, 2025 Barclays MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.23 ▲ +22.0% $-0.28 — $-0.20 38% YoY 4
Next Q $-0.25 ▲ +14.4% $-0.29 — $-0.21 15% YoY 4
Current FY $-0.96 ▲ +14.1% $-1.06 — $-0.83 16% YoY 5
Next FY $-1.04 ▲ +17.5% $-1.15 — $-0.93 -9% YoY 4

Top Institutional Holders

FundValueMove
MORGAN STANLEY$23.9MADD
RA CAPITAL MANAGEMENT, L.P.$21.0MNEW
VANGUARD CAPITAL MANAGEMENT LLC$10.2M
TWO SIGMA INVESTMENTS, LP$8.0MADD
WASATCH ADVISORS LP$7.8MTRIM

Recent Insider Trades

DateInsiderTypeValue
Jun 1, 2026Anderson KennethM$2.3K
Apr 1, 2026Anderson KennethA$11.5K
Apr 1, 2026GROGAN DONNAA$14.5K
50 institutional holders with $124.3M total value (47,418,563 shares) as of 2026-Q1. Top holders: MORGAN, RA, VANGUARD. Net buying activity: 6 institutions added/increased vs 4 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1MORGAN STANLEY9,072,400$23.9M19.2%ADD +80.6%
2RA CAPITAL MANAGEMENT, L.P.8,000,000$21.0M16.9%NEW
3VANGUARD CAPITAL MANAGEMENT LLC3,861,852$10.2M8.2%
4TWO SIGMA INVESTMENTS, LP3,035,634$8.0M6.4%ADD +80.9%
5WASATCH ADVISORS LP2,961,761$7.8M6.3%TRIM -31.8%
6CITADEL ADVISORS LLC2,511,015$6.6M5.3%
7RENAISSANCE TECHNOLOGIES LLC2,461,815$6.5M5.2%ADD +53.6%
8GOLDMAN SACHS GROUP INC2,387,378$6.3M5.1%
9BANK OF AMERICA CORP /DE/2,359,241$6.2M5.0%
10BlackRock, Inc.2,048,526$5.4M4.3%
11SUSQUEHANNA INTERNATIONAL GROUP, LLP1,286,840$3.4M2.7%
12D. E. Shaw & Co., Inc.1,060,331$2.8M2.2%DOUBLED +345.7%
13WELLS FARGO & COMPANY/MN867,911$2.3M1.8%DOUBLED +4236.9%
14CONGRESS ASSET MANAGEMENT CO830,624$2.2M1.8%
15VANGUARD FIDUCIARY TRUST CO484,131$1.3M1.0%
16CHARLES SCHWAB INVESTMENT MANAGEMENT INC452,228$1.2M1.0%ADD +28.2%
17DIMENSIONAL FUND ADVISORS LP442,518$1.2M0.9%ADD +49.3%
18STATE STREET CORP382,973$1.0M0.8%NEAR_EXIT -76.5%
19BARCLAYS PLC317,877$836.0K0.7%TRIM -57.4%
20Connor, Clark & Lunn Investment Management Ltd.277,183$729.0K0.6%DOUBLED +634.8%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
WASATCH ADVISORS LPTRIM4,344,9182,961,761-31.8%$7.8M2026-Q1
RENAISSANCE TECHNOLOGIES LLCADD1,602,5802,461,815+53.6%$6.5M2026-Q1
DIMENSIONAL FUND ADVISORS LPADD296,480442,518+49.3%$1.2M2026-Q1
Connor, Clark & Lunn Investment Management Ltd.DOUBLED37,721277,183+634.8%$729.0K2026-Q1
Point72 Asset Management, L.P.NEAR_EXIT9,439,328169,096-98.2%$444.7K2026-Q1
MARSHALL WACE, LLPTRIM265,027155,495-41.3%$409.0K2026-Q1
CANADA PENSION PLAN INVESTMENT BOARDDOUBLED29,500135,600+359.7%$356.6K2026-Q1
Jain Global LLCDOUBLED12,76262,390+388.9%$164.1K2026-Q1
OMERS ADMINISTRATION CorpTRIM117,70059,700-49.3%$157.0K2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/DOUBLED12,40071,546+477.0%$189.002026-Q1
Point72 Asset Management, L.P.NEW9,439,328$18.0M2025-Q4
MORGAN STANLEYADD4,972,0328,981,662+80.6%$17.2M2025-Q4
RA CAPITAL MANAGEMENT, L.P.NEW8,000,000$15.3M2025-Q4
VANGUARD GROUP INCADD3,191,5574,379,815+37.2%$8.4M2025-Q4
RENAISSANCE TECHNOLOGIES LLCADD936,9501,602,580+71.0%$3.1M2025-Q4
TWO SIGMA INVESTMENTS, LPADD834,7261,509,603+80.9%$2.9M2025-Q4
WELLS FARGO & COMPANY/MNDOUBLED18,660809,260+4236.9%$1.5M2025-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD350,606449,432+28.2%$858.4K2025-Q4
Invesco Ltd.ADD191,820268,350+39.9%$512.5K2025-Q4
MARSHALL WACE, LLPDOUBLED106,275265,027+149.4%$506.2K2025-Q4
D. E. Shaw & Co., Inc.DOUBLED11,86352,879+345.7%$101.0K2025-Q4
GROUP ONE TRADING LLCDOUBLED12,43238,994+213.7%$74.5K2025-Q4
Mirae Asset Global Investments Co., Ltd.ADD2,7514,709+71.2%$9.0K2025-Q4
CWM, LLCNEAR_EXIT10,156146-98.6%2025-Q3
WASATCH ADVISORS LPTRIM7,424,6624,852,741-34.6%$10.8M2025-Q3
2 unique insiders with 3 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 1, 2026Anderson Kenneth CarlDirectorEXERCISE1,070$2.11$2.3K
Apr 1, 2026Anderson Kenneth CarlDirectorAWARD4,259$2.70$11.5K
Apr 1, 2026GROGAN DONNA ROYDirectorAWARD5,370$2.70$14.5K
Current analyst consensus: Strong Buy (93% buy). Based on 14 analysts: 5 strong buy, 8 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$13.33 mean target +241.9% upside Strong Buy (1.14)
$7.00 Low $30.00 High
MetricValue
Current Price$3.90
Target Low$7.00
Target Mean$13.33
Target Median$11.00
Target High$30.00
# Analysts6
RecommendationStrong Buy (1.14)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.23 $-0.28 $-0.20 37.8% +22.0% 1↑ 0↓ $0.0B -38.1% 4
Next Q
2026-09-30
$-0.25 $-0.29 $-0.21 14.5% +14.4% $0.0B -59.3% 4
Current FY
2026-12-31
$-0.96 $-1.06 $-0.83 15.9% +14.1% 1↑ 1↓ $0.0B -47.3% 5
Next FY
2027-12-31
$-1.04 $-1.15 $-0.93 -8.8% +17.5% 1↑ 1↓ $0.0B 1.1% 4

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.230
7d ago$-0.240+0.010
30d ago$-0.295+0.065
60d ago$-0.295+0.065
90d ago$-0.330+0.100
3 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jun 1, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
Feb 27, 2026 Barclays MAINTAIN Overweight Overweight
Feb 23, 2026 Brookline Capital MAINTAIN Buy Buy
Dec 17, 2025 Barclays MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20265810093%
May 1, 20265810093%
Apr 1, 20265810093%
Mar 1, 20265810093%
Feb 1, 20265810093%
Jan 1, 20265810093%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 11, 2026
fda
C4 Therapeutics Presents Phase 1 Data at European Hematology Association (EHA) 2026 Congress Highlighting Cemsidomide as a Potential Best-in-Class IKZF1/3 Degrader for Multiple Myeloma in Heavily Pretreated Relapsed/Refractory Population
<p align="center"><em>At the 100 µg Recommended Phase 2 Dose (RP2D), Cemsidomide Demonstrated a 53% Overall Response Rate, Including Complete Response
Jun 8, 2026
short_volume
Short Volume: CCCC — 55.4% short (0.5M / 1.0M)
Short: 547,344 | Exempt: 437 | TRF Vol: 987,213 | Short Ratio: 55.4% | Off-exchange volume (dark pool + OTC)
May 20, 2026
other
C4 Therapeutics to Participate in Upcoming Conferences
<p>WATERTOWN, Mass., May 20, 2026 (GLOBE NEWSWIRE) -- C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicat
May 18, 2026
activist
C4 Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
<p>WATERTOWN, Mass., May 18, 2026 (GLOBE NEWSWIRE) -- C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicat
May 12, 2026
earnings
C4 Therapeutics Reports First Quarter 2026 Financial Results and Recent Business Highlights
<p align="left">WATERTOWN, Mass., May 12, 2026 (GLOBE NEWSWIRE) -- C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical co
May 5, 2026
earnings_calendar
CCCC Q1 2026 Earnings Scheduled — 2026-05-05
Apr 14, 2026
short_volume
Short Volume: CCCC — 55.9% short (1.3M / 2.3M)
Short: 1,298,206 | Exempt: 12,711 | TRF Vol: 2,322,095 | Short Ratio: 55.9% | Off-exchange volume (dark pool + OTC)
Apr 13, 2026
short_volume
Short Volume: CCCC — 60.4% short (2.0M / 3.3M)
Short: 1,985,225 | Exempt: 45,619 | TRF Vol: 3,286,945 | Short Ratio: 60.4% | Off-exchange volume (dark pool + OTC)
Apr 9, 2026
contract
C4 Therapeutics Expands Long-Term Partnership with Roche Through New Collaboration Agreement Focused on Discovering and Developing Degrader-Antibody Conjugates (DACs)
<p align="center"><em>Agreement Focused on Developing DACs With Payloads For Two Oncology Targets, With an Option for a Third Target</em></p>
Mar 25, 2026
fda
C4 Therapeutics Announces First Patient Dosed in Phase 1b Trial of Cemsidomide in Combination with Elranatamab (ELREXFIO®) for Relapsed/Refractory Multiple Myeloma
Novel Combination Regimen Positions Cemsidomide for Use in Earlier Lines of Therapy <pre>Novel Combination Regimen Positions Cemsidomide for Use in Ea
Mar 9, 2026
other
C4 Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
<p>WATERTOWN, Mass., March 09, 2026 (GLOBE NEWSWIRE) -- C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedic
Feb 25, 2026
earnings_calendar
CCCC Q4 2025 Earnings After Market Close — 2026-02-25