CTMX

CytomX Therapeutics, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001501989
$3.01 +1.01% $655.3M
Insider Selling Cluster (4 insiders)16 New Institutional Positions5 Institutional Exits
Vol
Market Cap$655.3M
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (93%)
Inst. Holders50 funds
Inst. Value$510.9M
Inst. Activity16 buys / 5 sells
Insider Activity0B / 4S
Insider Net $-$1.2M
Reddit Sentiment67° Warm
Press Releases4
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001501989·Prev Close $2.98

Recent Activity

Mar 17, 2026 Insider
Ogden Christopher sold 19,323 shares
Chief Financial Officer @ $6.42 ($124.1K)
Mar 17, 2026 Insider
BELVIN MARCIA sold 31,492 shares
SVP, Chief Scientific Officer @ $6.42 ($202.3K)
Mar 17, 2026 Insider
McCarthy Sean A. sold 118,969 shares
CEO @ $6.42 ($764.1K)
Inst.
FMR LLC — ADD
31,955,637 shares ($150.2M)
Inst.
BANK OF AMERICA CORP — DOUBLED
10,202,785 shares ($48.0M)
Jun 3, 2026 contract
CytomX Announces Expansion of Strategic Research Collaboration with Regeneron in the Field of Conditional Bispecific Therapeutics for the Treatment of Cancer
<p align="center"><em>- Expanded collaboration builds upon research momentum in developing next-gene
Mar 18, 2026 Press
CytomX Therapeutics priced a public offering of 45,990,567 shares and pre-funded warrants for 1,179,245 shares at $5.30
Impact 6/10
Mar 16, 2026 Press
CytomX Therapeutics announced a public offering of $250.0 million in common stock and pre-funded warrants, with an addit
Impact 7/10

Price Targets

$12.50 +315.3% upside Strong Buy
Current $3.01 Low $6.00 Median $12.00 High $16.00 8 analysts
$6.00 $16.00

Analyst Ratings

Strong Buy93% buy · 15 analysts
7Strong Buy
7Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 11, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
Mar 23, 2026 Piper Sandler MAINTAIN Overweight → Overweight
Mar 19, 2026 Barclays MAINTAIN Overweight → Overweight
Mar 18, 2026 Jefferies MAINTAIN Buy → Buy
Mar 18, 2026 Guggenheim MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.10 ▲ +1.2% $-0.13 — $-0.07 0% YoY 6
Next Q $-0.11 ▲ +4.5% $-0.14 — $-0.07 -17% YoY 6
Current FY $-0.42 ▲ +2.9% $-0.51 — $-0.34 -181% YoY 6
Next FY $-0.49 ▲ +2.1% $-0.81 — $-0.25 -15% YoY 7

Top Institutional Holders

FundValueMove
FMR LLC$150.2MADD
BANK OF AMERICA CORP$48.0MDOUBLED
VANGUARD CAPITAL MANAGEMENT LLC$41.0M
Point72 Asset Management, L.P.$37.0MADD
STATE STREET CORP$26.6MDOUBLED

Recent Insider Trades

DateInsiderTypeValue
Mar 17, 2026Ogden ChristopherSELL$124.1K
Mar 17, 2026BELVIN MARCIASELL$202.3K
Mar 17, 2026McCarthy SeanSELL$764.1K
Mar 17, 2026Chu Yu-WayeSELL$136.7K
Feb 2, 2026Chu Yu-WayeA$0.00

Reddit Sentiment

67°
Warm
Bearish Neutral Bullish
2 mentions 2 bullish 0 bearish
50 institutional holders with $510.9M total value (108,708,510 shares) as of 2026-Q1. Top holders: FMR, BANK, VANGUARD. Net buying activity: 16 institutions added/increased vs 5 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1FMR LLC31,955,637$150.2M29.4%ADD +29.4%
2BANK OF AMERICA CORP /DE/10,202,785$48.0M9.4%DOUBLED +676.2%
3VANGUARD CAPITAL MANAGEMENT LLC8,733,118$41.0M8.0%
4Point72 Asset Management, L.P.7,875,390$37.0M7.2%ADD +51.8%
5STATE STREET CORP5,663,408$26.6M5.2%DOUBLED +697.1%
6CITADEL ADVISORS LLC5,406,193$25.4M5.0%DOUBLED +2005.6%
7BlackRock, Inc.5,228,280$24.6M4.8%ADD +42.5%
8BAKER BROS. ADVISORS LP4,975,826$23.4M4.6%
9MARSHALL WACE, LLP4,138,176$19.4M3.8%DOUBLED +257.7%
10WELLINGTON MANAGEMENT GROUP LLP3,582,985$16.8M3.3%NEW
11TWO SIGMA INVESTMENTS, LP2,710,156$12.7M2.5%DOUBLED +113.9%
12Woodline Partners LP2,000,825$9.4M1.8%
13DIMENSIONAL FUND ADVISORS LP1,930,920$9.1M1.8%ADD +49.7%
14SUSQUEHANNA INTERNATIONAL GROUP, LLP1,869,615$8.8M1.7%
15GOLDMAN SACHS GROUP INC1,459,839$6.9M1.3%
16VANGUARD FIDUCIARY TRUST CO1,102,883$5.2M1.0%
17SUSQUEHANNA INTERNATIONAL GROUP, LLP907,800$4.3M0.8%
18Trexquant Investment LP898,767$4.2M0.8%
19VANGUARD PORTFOLIO MANAGEMENT LLC794,755$3.7M0.7%
20BALYASNY ASSET MANAGEMENT L.P.730,844$3.4M0.7%NEAR_EXIT -81.1%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
FMR LLCADD24,688,10931,955,637+29.4%$150.2M2026-Q1
BANK OF AMERICA CORP /DE/DOUBLED876,30510,202,785+676.2%$48.0M2026-Q1
Point72 Asset Management, L.P.ADD5,189,5387,875,390+51.8%$37.0M2026-Q1
BlackRock, Inc.ADD3,669,3935,228,280+42.5%$24.6M2026-Q1
MARSHALL WACE, LLPDOUBLED1,156,9364,138,176+257.7%$19.4M2026-Q1
WELLINGTON MANAGEMENT GROUP LLPNEW3,582,985$16.8M2026-Q1
DIMENSIONAL FUND ADVISORS LPADD1,289,6561,930,920+49.7%$9.1M2026-Q1
BALYASNY ASSET MANAGEMENT L.P.NEAR_EXIT3,872,202730,844-81.1%$3.4M2026-Q1
FIRST TRUST ADVISORS LPADD423,168568,562+34.4%$2.7M2026-Q1
MORGAN STANLEYADD401,191520,495+29.7%$2.4M2026-Q1
Assenagon Asset Management S.A.TRIM592,696364,173-38.6%$1.7M2026-Q1
Brevan Howard Capital Management LPDOUBLED11,404269,202+2260.6%$1.3M2026-Q1
SEI INVESTMENTS CODOUBLED124,124248,248+100.0%$1.2M2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD68,687128,796+87.5%$605.3K2026-Q1
Jain Global LLCDOUBLED21,212104,750+393.8%$492.3K2026-Q1
Hudson Bay Capital Management LPADD50,99080,663+58.2%$379.1K2026-Q1
AMERIPRISE FINANCIAL INCTRIM229,59965,015-71.7%$305.9K2026-Q1
OMERS ADMINISTRATION CorpTRIM87,80062,400-28.9%$293.3K2026-Q1
Invesco Ltd.DOUBLED21,97661,555+180.1%$289.3K2026-Q1
HB Wealth Management, LLCDOUBLED25,00050,000+100.0%$235.0K2026-Q1
Financial Engines Advisors L.L.C.EXIT3,828,7170-100.0%$0.002026-Q1
FMR LLCADD15,396,20024,688,109+60.4%$105.2M2025-Q4
Point72 Asset Management, L.P.ADD4,068,5755,189,538+27.6%$22.1M2025-Q4
STATE STREET CORPDOUBLED644,9825,140,931+697.1%$21.9M2025-Q4
Financial Engines Advisors L.L.C.DOUBLED1,381,3573,828,717+177.2%$16.3M2025-Q4
5 unique insiders with 15 transactions. Net insider value: -$1.2M ($0.00 bought, $1.2M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Mar 17, 2026Ogden ChristopherChief Financial OfficerSELL19,323$6.42$124.1K
Mar 17, 2026BELVIN MARCIASVP, Chief Scientific OfficerSELL31,492$6.42$202.3K
Mar 17, 2026McCarthy Sean A.CEOSELL118,969$6.42$764.1K
Mar 17, 2026Chu Yu-WayeChief Medical OfficerSELL21,279$6.42$136.7K
Feb 2, 2026Chu Yu-WayeChief Medical OfficerAWARD75,000
Feb 2, 2026Chu Yu-WayeChief Medical OfficerAWARD300,000
Feb 2, 2026Lester RachaelChief Business OfficerAWARD20,000
Feb 2, 2026Lester RachaelChief Business OfficerAWARD50,000
Feb 2, 2026Lester RachaelChief Business OfficerAWARD50,000
Feb 2, 2026BELVIN MARCIASVP, Chief Scientific OfficerAWARD60,000
Feb 2, 2026BELVIN MARCIASVP, Chief Scientific OfficerAWARD250,000
Feb 2, 2026Ogden ChristopherChief Financial OfficerAWARD90,000
Feb 2, 2026Ogden ChristopherChief Financial OfficerAWARD325,000
Feb 2, 2026McCarthy Sean A.CEOAWARD210,000
Feb 2, 2026McCarthy Sean A.CEOAWARD980,000

No SEC filing reports analyzed yet. Reports are generated when new filings are detected and processed by the LLM pipeline.

Current analyst consensus: Strong Buy (93% buy). Based on 15 analysts: 7 strong buy, 7 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$12.50 mean target +315.3% upside Strong Buy (1.38)
$6.00 Low $16.00 High
MetricValue
Current Price$3.01
Target Low$6.00
Target Mean$12.50
Target Median$12.00
Target High$16.00
# Analysts8
RecommendationStrong Buy (1.38)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.10 $-0.13 $-0.07 0.0% +1.2% 2↑ 4↓ $0.0B -33.9% 6
Next Q
2026-09-30
$-0.11 $-0.14 $-0.07 -16.9% +4.5% 3↑ 3↓ $0.0B 3.4% 6
Current FY
2026-12-31
$-0.42 $-0.51 $-0.34 -180.6% +2.9% 2↑ 4↓ $0.0B -53.1% 6
Next FY
2027-12-31
$-0.49 $-0.81 $-0.25 -15.4% +2.1% 3↑ 3↓ $0.0B -4.2% 7

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.101
7d ago$-0.104+0.003
30d ago$-0.102+0.001
60d ago$-0.067-0.034
90d ago$-0.056-0.045
8 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 11, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Mar 23, 2026 Piper Sandler MAINTAIN Overweight Overweight
Mar 19, 2026 Barclays MAINTAIN Overweight Overweight
Mar 18, 2026 Jefferies MAINTAIN Buy Buy
Mar 18, 2026 Guggenheim MAINTAIN Buy Buy
Mar 17, 2026 Wedbush MAINTAIN Outperform Outperform
Mar 16, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Mar 16, 2026 JP Morgan UPGRADE Neutral Overweight
Mar 9, 2026 Guggenheim REITERATE Buy Buy
Feb 4, 2026 Cantor Fitzgerald MAINTAIN Overweight Overweight
Feb 4, 2026 Barclays MAINTAIN Overweight Overweight
Jan 20, 2026 Barclays MAINTAIN Overweight Overweight
Jan 20, 2026 Guggenheim INITIATE Buy
Jan 20, 2026 Piper Sandler MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20267710093%
May 1, 20266810093%
Apr 1, 20266810093%
Mar 1, 20266720087%
Feb 1, 20266720087%
Jan 1, 20265720086%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

67°
Warm
Bearish Neutral Bullish
2 mentions 2 bullish 0 bearish 2 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 5, 2026160° Warm101
May 5, 2026160° Warm101

Recent Reddit Threads

r/pennystocks Bullish 1mo ago
CTMX is having their Q1 announcement on the 7th
▲ 1 💬 1 ⚡ 0.5
Jun 3, 2026
contract
CytomX Announces Expansion of Strategic Research Collaboration with Regeneron in the Field of Conditional Bispecific Therapeutics for the Treatment of Cancer
<p align="center"><em>- Expanded collaboration builds upon research momentum in developing next-generation bispecific immunotherapies using CytomX’s P
Jun 2, 2026
short_volume
Short Volume: CTMX — 57.8% short (1.2M / 2.1M)
Short: 1,214,084 | Exempt: 37 | TRF Vol: 2,099,354 | Short Ratio: 57.8% | Off-exchange volume (dark pool + OTC)
May 28, 2026
short_volume
Short Volume: CTMX — 55.9% short (0.6M / 1.1M)
Short: 628,037 | Exempt: 5,000 | TRF Vol: 1,123,846 | Short Ratio: 55.9% | Off-exchange volume (dark pool + OTC)
May 27, 2026
short_volume
Short Volume: CTMX — 67.2% short (1.7M / 2.5M)
Short: 1,652,139 | Exempt: 0 | TRF Vol: 2,459,891 | Short Ratio: 67.2% | Off-exchange volume (dark pool + OTC)
May 21, 2026
other
CytomX Therapeutics to Present at Upcoming June Investor Conferences
<p align="left">SOUTH SAN FRANCISCO, Calif., May 21, 2026 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of mas
May 7, 2026
earnings
CytomX Therapeutics Announces Q1 2026 Financial Results and Provides Business Update
<p align="center"><em>- Positive data announced from Phase 1 Dose Expansion Study of varsetatug masetecan (“Varseta-M”) EpCAM PROBODY® ADC in Patients
May 4, 2026
short_volume
Short Volume: CTMX — 58.6% short (0.6M / 1.0M)
Short: 577,300 | Exempt: 0 | TRF Vol: 984,994 | Short Ratio: 58.6% | Off-exchange volume (dark pool + OTC)
Apr 30, 2026
earnings_calendar
CTMX Q1 2026 Earnings Scheduled — 2026-04-30
Apr 29, 2026
short_volume
Short Volume: CTMX — 65.5% short (0.5M / 0.7M)
Short: 468,847 | Exempt: 0 | TRF Vol: 716,292 | Short Ratio: 65.5% | Off-exchange volume (dark pool + OTC)
Apr 28, 2026
short_volume
Short Volume: CTMX — 75.8% short (1.0M / 1.4M)
Short: 1,039,514 | Exempt: 0 | TRF Vol: 1,370,596 | Short Ratio: 75.8% | Off-exchange volume (dark pool + OTC)
Apr 27, 2026
short_volume
Short Volume: CTMX — 72.4% short (0.8M / 1.1M)
Short: 823,878 | Exempt: 0 | TRF Vol: 1,137,958 | Short Ratio: 72.4% | Off-exchange volume (dark pool + OTC)
Apr 24, 2026
short_volume
Short Volume: CTMX — 56.9% short (0.5M / 0.8M)
Short: 476,404 | Exempt: 0 | TRF Vol: 837,948 | Short Ratio: 56.9% | Off-exchange volume (dark pool + OTC)
Apr 21, 2026
short_volume
Short Volume: CTMX — 61.4% short (0.9M / 1.5M)
Short: 942,713 | Exempt: 7,030 | TRF Vol: 1,534,782 | Short Ratio: 61.4% | Off-exchange volume (dark pool + OTC)
Apr 14, 2026
short_volume
Short Volume: CTMX — 58.6% short (2.1M / 3.6M)
Short: 2,135,832 | Exempt: 0 | TRF Vol: 3,646,273 | Short Ratio: 58.6% | Off-exchange volume (dark pool + OTC)
Apr 13, 2026
short_volume
Short Volume: CTMX — 61.3% short (1.9M / 3.2M)
Short: 1,932,659 | Exempt: 275 | TRF Vol: 3,150,714 | Short Ratio: 61.3% | Off-exchange volume (dark pool + OTC)