LXEO

Lexeo Therapeutics, Inc.

Nasdaq · Biological Products, (No Diagnostic Substances) · CIK 0001907108
$4.21 -3.66% $332.9M
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)7 New Institutional Positions
Vol
Market Cap$332.9M
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (94%)
Inst. Holders8 funds
Inst. Value$50.5M
Inst. Activity7 buys / 0 sells
Insider Activity0B / 6S
Insider Net $-$427.6K
SEC Reports4
Press Releases1
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·CIK 0001907108·Prev Close $4.37

Recent Activity

May 20, 2026 SEC
Two LXEO insiders — CEO and COO — sold a combined $24K in open-market sales on the same day, 9 days after Q1 2026 earnin
CLUSTER — Impact 2/10
May 20, 2026 short_volume
Short Volume: LXEO — 91.4% short (0.8M / 0.9M)
Short: 799,209 | Exempt: 0 | TRF Vol: 874,254 | Short Ratio: 91.4% | Off-exchange volume (dark pool
May 18, 2026 Insider
Townsend Richard Nolan sold 3,342 shares
Chief Executive Officer @ $5.06 ($16.9K)
May 18, 2026 Insider
Otero Jose Manuel sold 1,302 shares
Chief Operating Officer @ $5.07 ($6.6K)
May 11, 2026 SEC
Lexeo Therapeutics reported Q1 2026 results with a net loss of $20.2M ($0.25 per share), narrowing from $32.7M ($0.99 pe
8-K — Impact 6/10
May 11, 2026 SEC
Lexeo Therapeutics reported Q1 2026 net loss of $0.25 per share, beating consensus estimates of -$0.30 by 16.7%, with re
PRESS-RELEASE — Impact 6/10
Apr 28, 2026 Insider
Sepp-Lorenzino Laura sold 50,000 shares
Director @ $0.00 ($0.00)
Inst.
VANGUARD GROUP INC — ADD
3,894,310 shares ($38.7M)

Price Targets

$20.60 +385.8% upside Strong Buy
Current $4.24 Low $12.00 Median $19.50 High $30.00 10 analysts
$12.00 $30.00

Analyst Ratings

Strong Buy94% buy · 16 analysts
8Strong Buy
7Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 11, 2026 Chardan Capital MAINTAIN Buy → Buy
Jan 13, 2026 Chardan Capital MAINTAIN Buy → Buy
Jan 13, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
Dec 18, 2025 Raymond James INITIATE Strong Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.28 ▲ +10.3% $-0.32 — $-0.24 59% YoY 6
Next Q $-0.31 ▲ +10.4% $-0.39 — $-0.26 5% YoY 8
Current FY $-1.14 ▲ +11.5% $-1.28 — $-0.99 41% YoY 6
Next FY $-1.31 ▲ +7.7% $-1.77 — $-0.74 -10% YoY 8

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$38.7MADD
TWO SIGMA INVESTMENTS, LP$4.0MDOUBLED
RENAISSANCE TECHNOLOGIES LLC$2.2MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$1.9MADD
BANK OF AMERICA CORP$1.6MDOUBLED

Recent Insider Trades

DateInsiderTypeValue
May 18, 2026Townsend RichardSELL$16.9K
May 18, 2026Otero JoseSELL$6.6K
Apr 28, 2026Sepp-Lorenzino LauraA$0.00
Apr 6, 2026Townsend RichardSELL$313.1K
Mar 13, 2026Otero JoseA$15.7K
8 institutional holders with $50.5M total value (5,089,452 shares) as of 2025-Q4. Top holders: VANGUARD, TWO, RENAISSANCE. Net buying activity: 7 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC3,894,310$38.7M76.5%ADD +74.9%
2TWO SIGMA INVESTMENTS, LP400,567$4.0M7.9%DOUBLED +372.6%
3RENAISSANCE TECHNOLOGIES LLC217,772$2.2M4.3%ADD +45.9%
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC192,210$1.9M3.8%ADD +81.7%
5BANK OF AMERICA CORP /DE/160,288$1.6M3.1%DOUBLED +466.8%
6MORGAN STANLEY140,181$1.4M2.8%ADD +43.0%
7WELLS FARGO & COMPANY/MN70,736$702.4K1.4%DOUBLED +267.2%
8FMR LLC13,388$132.9K0.3%DOUBLED +392.5%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
VANGUARD GROUP INCADD2,226,2903,894,310+74.9%$38.7M2025-Q4
TWO SIGMA INVESTMENTS, LPDOUBLED84,763400,567+372.6%$4.0M2025-Q4
RENAISSANCE TECHNOLOGIES LLCADD149,300217,772+45.9%$2.2M2025-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD105,760192,210+81.7%$1.9M2025-Q4
BANK OF AMERICA CORP /DE/DOUBLED28,279160,288+466.8%$1.6M2025-Q4
MORGAN STANLEYADD98,057140,181+43.0%$1.4M2025-Q4
WELLS FARGO & COMPANY/MNDOUBLED19,26270,736+267.2%$702.4K2025-Q4
RENAISSANCE TECHNOLOGIES LLCADD106,200149,300+40.6%$991.4K2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD64,220105,760+64.7%$702.2K2025-Q3
WELLS FARGO & COMPANY/MNADD15,32519,262+25.7%$127.9K2025-Q3
VANGUARD GROUP INCADD1,099,2852,002,866+82.2%$8.1M2025-Q2
UBS Group AGDOUBLED32,082271,904+747.5%$1.1M2025-Q2
RENAISSANCE TECHNOLOGIES LLCDOUBLED20,300106,200+423.2%$426.9K2025-Q2
TWO SIGMA INVESTMENTS, LPADD36,62469,242+89.1%$278.4K2025-Q2
WELLS FARGO & COMPANY/MNADD11,40915,325+34.3%$61.6K2025-Q2
TWO SIGMA INVESTMENTS, LPNEW36,624$127.1K2025-Q1
UBS Group AGTRIM51,05432,082-37.2%$111.3K2025-Q1
RENAISSANCE TECHNOLOGIES LLCNEW20,300$70.4K2025-Q1
FMR LLCDOUBLED2,0039,864+392.5%$34.2K2025-Q1
MORGAN STANLEYTRIM241,82874,828-69.1%$492.4K2024-Q4
UBS Group AGDOUBLED11,11251,054+359.4%$335.9K2024-Q4
WELLS FARGO & COMPANY/MNADD7,44211,156+49.9%$73.4K2024-Q4
MORGAN STANLEYDOUBLED12,663241,828+1809.7%$2.2M2024-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW63,874$577.4K2024-Q3
5 unique insiders with 6 transactions. Net insider value: -$427.6K ($0.00 bought, $427.6K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 18, 2026Townsend Richard NolanChief Executive OfficerSELL3,342$5.06$16.9K
May 18, 2026Otero Jose ManuelChief Operating OfficerSELL1,302$5.07$6.6K
Apr 28, 2026Sepp-Lorenzino LauraDirectorA50,000$0.00$0.00
Apr 6, 2026Townsend Richard NolanChief Executive OfficerSELL55,000$5.69$313.1K
Mar 13, 2026Otero Jose ManuelChief Operating OfficerA5,930$2.64$15.7K
Mar 13, 2026Townsend Richard NolanChief Executive OfficerA2,623$2.64$6.9K
Feb 18, 2026Otero Jose ManuelChief Operating OfficerSELL3,016$6.40$19.3K
Feb 18, 2026Townsend Richard NolanChief Executive OfficerSELL10,173$6.38$64.9K
Feb 13, 2026Bhalla Narinder PalChief Medical OfficerA49,500$0.00$0.00
Feb 13, 2026Bhalla Narinder PalChief Medical OfficerA297,000$0.00$0.00
Feb 4, 2026Otero Jose ManuelChief Operating OfficerA65,000$0.00$0.00
Feb 4, 2026Otero Jose ManuelChief Operating OfficerA260,000$0.00$0.00
Feb 4, 2026Townsend Richard NolanChief Executive OfficerA161,665$0.00$0.00
Feb 4, 2026Townsend Richard NolanChief Executive OfficerA646,665$0.00$0.00
Feb 4, 2026Tamayo Louis EdwardChief Financial OfficerA44,665$0.00$0.00
Feb 4, 2026Tamayo Louis EdwardChief Financial OfficerA226,665$0.00$0.00
Nov 18, 2025Otero Jose ManuelChief Operating OfficerSELL721$9.27$6.7K
Current analyst consensus: Strong Buy (94% buy). Based on 16 analysts: 8 strong buy, 7 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$20.60 mean target +385.8% upside Strong Buy (3.00)
$12.00 Low $30.00 High
MetricValue
Current Price$4.24
Target Low$12.00
Target Mean$20.60
Target Median$19.50
Target High$30.00
# Analysts10
RecommendationStrong Buy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.28 $-0.32 $-0.24 59.1% +10.3% 3↑ 0↓ $0.0B 0.0% 6
Next Q
2026-09-30
$-0.31 $-0.39 $-0.26 5.4% +10.4% 7↑ 0↓ $0.0B 0.0% 8
Current FY
2026-12-31
$-1.14 $-1.28 $-0.99 41.1% +11.5% 3↑ 0↓ $0.0B 0.0% 6
Next FY
2027-12-31
$-1.31 $-1.77 $-0.74 -10.5% +7.7% 4↑ 0↓ $0.0B 0.0% 8

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.277
7d ago$-0.283+0.006
30d ago$-0.308+0.032
60d ago$-0.347+0.070
90d ago$-0.347+0.070
3 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 11, 2026 Chardan Capital MAINTAIN Buy Buy
Jan 13, 2026 Chardan Capital MAINTAIN Buy Buy
Jan 13, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Dec 18, 2025 Raymond James INITIATE Strong Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20268710094%
May 1, 20268810094%
Apr 1, 20268810094%
Mar 1, 20268810094%
Feb 1, 20268810094%
Jan 1, 20268810094%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 20, 2026
short_volume
Short Volume: LXEO — 91.4% short (0.8M / 0.9M)
Short: 799,209 | Exempt: 0 | TRF Vol: 874,254 | Short Ratio: 91.4% | Off-exchange volume (dark pool + OTC)
May 11, 2026
earnings
Lexeo Therapeutics Reports First Quarter 2026 Financial Results and Operational Highlights
1Q 2026 Earnings
May 11, 2026
earnings_calendar
LXEO Q1 2026 Earnings Scheduled — 2026-05-11
May 7, 2026
earnings_calendar
LXEO Q1 2026 Earnings Scheduled — 2026-05-07
Apr 27, 2026
routine
Lexeo Therapeutics Announces Multiple Presentations at the 29th American Society of Gene & Cell Therapy (ASGCT) Annual Meeting
ASGCT 2026 Abstracts
Mar 30, 2026
earnings
Lexeo Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Operational Highlights
Lexeo Earnings release
Mar 16, 2026
earnings_calendar
LXEO Q4 2025 Earnings Before Market Open — 2026-03-16
Mar 3, 2026
other
Lexeo Therapeutics to Participate in the Leerink Global Healthcare Conference
Lexeo Therapeutics to Participate in the Leerink Global Healthcare Conference