OBIO

Orchestra BioMed Holdings, Inc.

Nasdaq · Surgical & Medical Instruments & Apparatus · Inc. DE · CIK 0001814114
$3.90 -2.26% $238.9M
Insider Selling Cluster (3 insiders)3 New Institutional Positions
Vol
Market Cap$238.9M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (85%)
Inst. Holders6 funds
Inst. Value$9.2M
Inst. Activity3 buys / 2 sells
Insider Activity6B / 2S
Insider Net $$142.8K
SEC Reports3
Press Releases2
Exchange Nasdaq·Sector Surgical & Medical Instruments & Apparatus·Inc. DE·CIK 0001814114·Prev Close $3.99

Recent Activity

Jun 2, 2026 SEC
Two insiders at Orchestra BioMed traded in opposite directions on the same day: Director Hochman bought $19K worth of sh
CLUSTER — Impact 2/10
Jun 2, 2026 other
Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">NEW HOPE, Pa., June 02, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc
Jun 1, 2026 Insider
Sherman Darren sold 15,000 shares
See Remarks @ $3.87 ($58.0K)
Jun 1, 2026 Insider
Hochman David P bought 5,000 shares
See Remarks @ $3.83 ($19.1K)
May 28, 2026 Insider
Sherman Darren sold 4,925 shares
See Remarks @ $3.98 ($19.6K)
May 19, 2026 SEC
Two directors and one officer made small open-market purchases of OBIO shares totaling ~$136K, representing only ~0.06%
CLUSTER — Impact 2/10
Apr 29, 2026 SEC
Orchestra BioMed Holdings, Inc. filed definitive additional proxy materials for its 2026 Annual Meeting, scheduled for J
DEFA14A — Impact 2/10
Inst.
CHARLES SCHWAB INVESTMENT MANAGEMENT — ADD
263,788 shares ($1.1M)

Price Targets

$12.17 +212.0% upside Strong Buy
Current $3.90 Low $9.00 Median $10.00 High $20.00 6 analysts
$9.00 $20.00

Analyst Ratings

Strong Buy85% buy · 13 analysts
3Strong Buy
8Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 19, 2026 B. Riley Securities MAINTAIN Buy → Buy
May 14, 2026 HC Wainwright & Co. REITERATE Buy → Buy
May 13, 2026 Barclays MAINTAIN Overweight → Overweight
Mar 12, 2026 Chardan Capital MAINTAIN Buy → Buy
Jan 9, 2026 Barclays MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.37 ▲ +16.0% $-0.41 — $-0.28 26% YoY 5
Next Q $-0.38 ▲ +13.0% $-0.43 — $-0.32 4% YoY 5
Current FY $-1.50 $-1.60 — $-1.30 -35% YoY 5
Next FY $-1.46 $-1.81 — $-1.10 3% YoY 6

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$6.7MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$1.1MADD
RENAISSANCE TECHNOLOGIES LLC$627.9KTRIM
TWO SIGMA INVESTMENTS, LP$359.2KNEW
MORGAN STANLEY$339.7KDOUBLED

Recent Insider Trades

DateInsiderTypeValue
Jun 1, 2026Sherman DarrenSELL$58.0K
Jun 1, 2026Hochman DavidBUY$19.1K
May 28, 2026Sherman DarrenF$19.6K
May 28, 2026Taylor AndrewF$12.2K
May 18, 2026Aryeh JasonBUY$2.5K
6 institutional holders with $9.2M total value (2,205,594 shares) as of 2025-Q4. Top holders: VANGUARD, CHARLES, RENAISSANCE. Net buying activity: 3 institutions added/increased vs 2 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC1,604,556$6.7M72.7%ADD +28.0%
2CHARLES SCHWAB INVESTMENT MANAGEMENT INC263,788$1.1M12.0%ADD +46.2%
3RENAISSANCE TECHNOLOGIES LLC151,300$627.9K6.9%TRIM -60.2%
4TWO SIGMA INVESTMENTS, LP86,552$359.2K3.9%NEW
5MORGAN STANLEY81,851$339.7K3.7%DOUBLED +692.9%
6BANK OF AMERICA CORP /DE/17,547$72.8K0.8%TRIM -43.6%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD180,439263,788+46.2%$1.1M2025-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM380,508151,300-60.2%$627.9K2025-Q4
TWO SIGMA INVESTMENTS, LPNEW86,552$359.2K2025-Q4
MORGAN STANLEYDOUBLED10,32381,851+692.9%$339.7K2025-Q4
BANK OF AMERICA CORP /DE/TRIM31,11917,547-43.6%$72.8K2025-Q4
VANGUARD GROUP INCADD1,157,3171,481,875+28.0%$3.7M2025-Q3
RENAISSANCE TECHNOLOGIES LLCDOUBLED169,400380,508+124.6%$943.7K2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD138,591180,439+30.2%$447.5K2025-Q3
BANK OF AMERICA CORP /DE/ADD21,57731,119+44.2%$77.2K2025-Q3
UBS Group AGNEAR_EXIT26,1393,815-85.4%$9.5K2025-Q3
WELLS FARGO & COMPANY/MNEXIT4,4740-100.0%$0.002025-Q3
RENAISSANCE TECHNOLOGIES LLCNEW169,400$454.0K2025-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INCTRIM216,985138,591-36.1%$371.4K2025-Q2
UBS Group AGADD17,27026,139+51.4%$70.1K2025-Q2
BANK OF AMERICA CORP /DE/ADD15,89921,577+35.7%$57.8K2025-Q2
MORGAN STANLEYTRIM32,13413,382-58.4%$35.9K2025-Q2
WELLS FARGO & COMPANY/MNTRIM13,4534,474-66.7%$12.0K2025-Q2
FMR LLCADD1,0961,646+50.2%$4.4K2025-Q2
MORGAN STANLEYTRIM51,63132,134-37.8%$137.5K2025-Q1
CITADEL ADVISORS LLCADD12,27920,480+66.8%$87.7K2025-Q1
UBS Group AGTRIM24,06517,270-28.2%$73.9K2025-Q1
UBS Group AGDOUBLED11,48224,065+109.6%$96.3K2024-Q4
WELLS FARGO & COMPANY/MNADD9,16413,156+43.6%$52.6K2024-Q4
CITADEL ADVISORS LLCTRIM20,11512,279-39.0%$49.1K2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW217,008$1.1M2024-Q3
8 unique insiders with 8 transactions. Net insider value: $142.8K ($201.0K bought, $58.2K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 1, 2026Sherman DarrenSee RemarksSELL15,000$3.87$58.0K
Jun 1, 2026Hochman David PSee RemarksBUY5,000$3.83$19.1K
May 28, 2026Sherman DarrenSee RemarksF4,925$3.98$19.6K
May 28, 2026Taylor Andrew LawrenceChief Financial OfficerF3,076$3.98$12.2K
May 18, 2026Aryeh JasonDirectorBUY665$3.75$2.5K
May 15, 2026Hochman David PSee RemarksBUY5,000$3.77$18.9K
May 15, 2026Aryeh JasonDirectorBUY8,971$3.90$35.0K
May 14, 2026Fain Eric SDirectorBUY20,000$4.13$82.6K
Apr 27, 2026RTW INVESTMENTS, LP10%+ OwnerX1,250,032$0.000100$125.00
Apr 27, 2026RTW INVESTMENTS, LP10%+ OwnerSELL32$4.13$132.16
Apr 27, 2026RTW INVESTMENTS, LP10%+ OwnerX1,250,032$2.75$3.4M
Mar 25, 2026Aiello JoshuaPrincipal Accounting OfficerF241$4.57$1.1K
Mar 25, 2026Sherman DarrenSee RemarksF33,317$4.57$152.3K
Mar 25, 2026Hochman David PSee RemarksF32,438$4.57$148.2K
Mar 13, 2026Hochman David PSee RemarksBUY10,000$4.29$42.9K
Feb 12, 2026Taylor Andrew LawrenceChief Financial OfficerA181,000$0.00$0.00
Feb 12, 2026Sherman DarrenSee RemarksA397,000$0.00$0.00
Feb 12, 2026Aiello JoshuaPrincipal Accounting OfficerA70,000$0.00$0.00
Feb 12, 2026Hochman David PSee RemarksA504,000$0.00$0.00
Feb 5, 2026Cleary ChrisDirectorF676$3.71$2.5K
Jan 28, 2026Sherman DarrenSee RemarksA34,974$0.00$0.00
Current analyst consensus: Strong Buy (85% buy). Based on 13 analysts: 3 strong buy, 8 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$12.17 mean target +212.0% upside Strong Buy (1.43)
$9.00 Low $20.00 High
MetricValue
Current Price$3.90
Target Low$9.00
Target Mean$12.17
Target Median$10.00
Target High$20.00
# Analysts6
RecommendationStrong Buy (1.43)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.37 $-0.41 $-0.28 25.6% +16.0% 4↑ 1↓ $0.0B -85.7% 5
Next Q
2026-09-30
$-0.38 $-0.43 $-0.32 4.0% +13.0% 3↑ 1↓ $0.0B -86.9% 5
Current FY
2026-12-31
$-1.50 $-1.60 $-1.30 -34.8% 5↑ 0↓ $0.0B -98.6% 5
Next FY
2027-12-31
$-1.46 $-1.81 $-1.10 2.5% 2↑ 0↓ $0.0B 38.8% 6

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.372
7d ago$-0.391+0.019
30d ago$-0.443+0.071
60d ago$-0.443+0.071
90d ago$-0.398+0.026
5 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 19, 2026 B. Riley Securities MAINTAIN Buy Buy
May 14, 2026 HC Wainwright & Co. REITERATE Buy Buy
May 13, 2026 Barclays MAINTAIN Overweight Overweight
Mar 12, 2026 Chardan Capital MAINTAIN Buy Buy
Jan 9, 2026 Barclays MAINTAIN Overweight Overweight
Dec 10, 2025 TD Cowen INITIATE Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20263820085%
May 1, 20263920086%
Apr 1, 20263920086%
Mar 1, 20263920086%
Feb 1, 20263920086%
Jan 1, 20263920086%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 2, 2026
other
Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">NEW HOPE, Pa., June 02, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Compa
May 19, 2026
other
Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference
<p align="justify">NEW HOPE, Pa., May 19, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company
May 18, 2026
earnings_calendar
OBIO Q1 2026 Earnings Scheduled — 2026-05-18
May 12, 2026
earnings
Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates
<p align="justify">NEW HOPE, Pa., May 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company
May 11, 2026
earnings_calendar
OBIO Q1 2026 Earnings Scheduled — 2026-05-11
May 6, 2026
other
Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement
<p align="justify">NEW HOPE, Pa., May 06, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Compan
May 4, 2026
earnings_calendar
OBIO Q1 2026 Earnings Scheduled — 2026-05-04
Apr 23, 2026
fda
Orchestra BioMed to Present AVIM Therapy Clinical and Mechanistic Data at HRS 2026
<p align="justify">NEW HOPE, Pa., April 23, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Comp
Mar 12, 2026
earnings
Orchestra BioMed Reports Full Year 2025 Financial Results and Provides Fourth Quarter Business Update
<p align="justify">NEW HOPE, Pa., March 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Comp
Mar 3, 2026
other
Orchestra BioMed Announces Presentations Highlighting AVIM Therapy Potential Impact on Hypertensive Heart Disease and Heart Failure at THT and CRT
<p align="justify">NEW HOPE, Pa., March 03, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Comp