PALI

PALISADE BIO, INC.

Nasdaq · Biological Products, (No Diagnostic Substances) · Inc. DE · CIK 0001357459
$1.74 0.00% $293.3M
Insider Selling Cluster (2 insiders)5 New Institutional Positions
Vol
Market Cap$293.3M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (93%)
Inst. Holders7 funds
Inst. Value$20.5M
Inst. Activity5 buys / 0 sells
Insider Activity0B / 2S
Insider Net $-$10.3K
SEC Reports4
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·Inc. DE·CIK 0001357459·Prev Close $1.74

Recent Activity

May 22, 2026 SEC
Palisade Bio's $300M universal shelf registration (File No. 333-295815) became effective on May 21, 2026, enabling the c
EFFECT — Impact 4/10
May 12, 2026 SEC
Palisade Bio filed a $300M universal shelf registration statement on Form S-3, concurrent with its Q1 2026 earnings rele
S-3 — Impact 5/10
Apr 29, 2026 SEC
PALISADE BIO, INC. filed DEFA14A additional definitive proxy soliciting materials. The substantive content is embedded i
DEFA14A — Impact 2/10
Feb 12, 2026 Insider
Finley John David sold 3,896 shares
CEO, CFO @ $1.75 ($6.8K)
Feb 12, 2026 Insider
Jones Mitchell Lawrence sold 1,989 shares
Chief Medical Officer @ $1.75 ($3.5K)
Feb 11, 2026 Insider
Finley John David sold 13,333 shares
CEO, CFO @ $0.00 ($0.00)
Inst.
MORGAN STANLEY — DOUBLED
4,142,446 shares ($9.7M)
Inst.
RENAISSANCE TECHNOLOGIES LLC — NEW
2,382,500 shares ($5.6M)

Price Targets

$9.71 +474.8% upside Strong Buy
Current $1.69 Low $5.00 Median $7.00 High $25.00 7 analysts
$5.00 $25.00

Analyst Ratings

Strong Buy93% buy · 14 analysts
4Strong Buy
9Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Apr 9, 2026 Wolfe Research INITIATE Outperform
Mar 26, 2026 HC Wainwright & Co. INITIATE Buy
Feb 25, 2026 Stifel INITIATE Buy
Jan 9, 2026 B. Riley Securities INITIATE Buy
Dec 30, 2025 Clear Street INITIATE Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.05 ▼ -9.4% $-0.06 — $-0.04 91% YoY 6
Next Q $-0.05 ▲ +13.9% $-0.07 — $-0.04 86% YoY 6
Current FY $-0.21 ▼ -9.4% $-0.27 — $-0.18 30% YoY 6
Next FY $-0.23 ▲ +16.1% $-0.34 — $-0.18 -12% YoY 6

Top Institutional Holders

FundValueMove
MORGAN STANLEY$9.7MDOUBLED
RENAISSANCE TECHNOLOGIES LLC$5.6MNEW
VANGUARD GROUP INC$5.0MNEW
BANK OF AMERICA CORP$164.7KDOUBLED
TWO SIGMA INVESTMENTS, LP$65.0KNEW

Recent Insider Trades

DateInsiderTypeValue
Feb 12, 2026Finley JohnSELL$6.8K
Feb 12, 2026Jones MitchellSELL$3.5K
Feb 11, 2026Finley JohnM$0.00
Feb 11, 2026Finley JohnM$0.00
Feb 11, 2026Jones MitchellM$0.00
7 institutional holders with $20.5M total value (8,738,336 shares) as of 2025-Q4. Top holders: MORGAN, RENAISSANCE, VANGUARD. Net buying activity: 5 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1MORGAN STANLEY4,142,446$9.7M47.4%DOUBLED +47967.4%
2RENAISSANCE TECHNOLOGIES LLC2,382,500$5.6M27.3%NEW
3VANGUARD GROUP INC2,115,622$5.0M24.2%NEW
4BANK OF AMERICA CORP /DE/70,097$164.7K0.8%DOUBLED +81408.1%
5TWO SIGMA INVESTMENTS, LP27,640$65.0K0.3%NEW
6WELLS FARGO & COMPANY/MN21$49.000.0%
7FMR LLC10$24.000.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYDOUBLED8,6184,142,446+47967.4%$9.7M2025-Q4
RENAISSANCE TECHNOLOGIES LLCNEW2,382,500$5.6M2025-Q4
VANGUARD GROUP INCNEW2,115,622$5.0M2025-Q4
BANK OF AMERICA CORP /DE/DOUBLED8670,097+81408.1%$164.7K2025-Q4
TWO SIGMA INVESTMENTS, LPNEW27,640$65.0K2025-Q4
UBS Group AGDOUBLED33219,413+5747.3%$16.7K2025-Q3
MORGAN STANLEYDOUBLED78,618+123014.3%$7.4K2025-Q3
BANK OF AMERICA CORP /DE/ADD4586+91.1%$73.002025-Q3
UBS Group AGNEAR_EXIT38,083332-99.1%$226.002025-Q2
BANK OF AMERICA CORP /DE/ADD2345+95.7%$31.002025-Q2
MORGAN STANLEYNEAR_EXIT6287-98.9%$5.002025-Q2
UBS Group AGDOUBLED8,97438,083+324.4%$25.9K2025-Q1
MORGAN STANLEYDOUBLED7628+8871.4%$428.002025-Q1
UBS Group AGDOUBLED318,974+28848.4%$14.8K2024-Q4
MORGAN STANLEYNEAR_EXIT1407-95.0%$12.002024-Q4
2 unique insiders with 2 transactions. Net insider value: -$10.3K ($0.00 bought, $10.3K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Feb 12, 2026Finley John DavidCEO, CFOSELL3,896$1.75$6.8K
Feb 12, 2026Jones Mitchell LawrenceChief Medical OfficerSELL1,989$1.75$3.5K
Feb 11, 2026Finley John DavidCEO, CFOM13,333$0.00$0.00
Feb 11, 2026Finley John DavidCEO, CFOM13,333$0.00$0.00
Feb 11, 2026Jones Mitchell LawrenceChief Medical OfficerM8,000$0.00$0.00
Feb 11, 2026Jones Mitchell LawrenceChief Medical OfficerM8,000$0.00$0.00
Feb 9, 2026Jones Mitchell LawrenceChief Medical OfficerA787,000$0.00$0.00
Feb 9, 2026Finley John DavidCEO, CFOA2,011,000$0.00$0.00

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (93% buy). Based on 14 analysts: 4 strong buy, 9 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$9.71 mean target +474.8% upside Strong Buy (3.00)
$5.00 Low $25.00 High
MetricValue
Current Price$1.69
Target Low$5.00
Target Mean$9.71
Target Median$7.00
Target High$25.00
# Analysts7
RecommendationStrong Buy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.05 $-0.06 $-0.04 91.4% -9.4% 1↑ 3↓ $0.0B 0.0% 6
Next Q
2026-09-30
$-0.05 $-0.07 $-0.04 86.4% +13.9% 2↑ 1↓ $0.0B 0.0% 6
Current FY
2026-12-31
$-0.21 $-0.27 $-0.18 30.0% -9.4% 2↑ 2↓ $0.0B 0.0% 6
Next FY
2027-12-31
$-0.23 $-0.34 $-0.18 -11.9% +16.1% 3↑ 2↓ $0.0B 0.0% 6

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.050
7d ago$-0.050
30d ago$-0.046-0.004
60d ago$-0.052+0.002
90d ago$-0.057+0.007
6 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 6 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Apr 9, 2026 Wolfe Research INITIATE Outperform
Mar 26, 2026 HC Wainwright & Co. INITIATE Buy
Feb 25, 2026 Stifel INITIATE Buy
Jan 9, 2026 B. Riley Securities INITIATE Buy
Dec 30, 2025 Clear Street INITIATE Buy
Dec 29, 2025 Piper Sandler INITIATE Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20264910093%
May 1, 20264910093%
Apr 1, 20264910093%
Mar 1, 20264810092%
Feb 1, 20263810092%
Jan 1, 20263610090%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

Recent Reddit Threads

r/stocks Neutral 1mo ago
What's up with Palisade Bio [NASDAQ: PALI]
▲ 1 💬 0 ⚡ 0.5
Jun 9, 2026
other
Palisade Bio to Present on the Potential of PALI-2108 for Fibrostenotic Crohn’s Disease at New York Academy of Sciences Symposium
<p align="center"><i>Presentation to highlight fibrostenotic Crohn’s disease biology and the potential of a locally bioactivated PDE4 inhibitor prodru
Jun 9, 2026
short_volume
Short Volume: PALI — 67.0% short (0.6M / 0.8M)
Short: 555,167 | Exempt: 0 | TRF Vol: 829,002 | Short Ratio: 67.0% | Off-exchange volume (dark pool + OTC)
May 22, 2026
short_volume
Short Volume: PALI — 67.1% short (1.4M / 2.1M)
Short: 1,433,195 | Exempt: 100 | TRF Vol: 2,136,828 | Short Ratio: 67.1% | Off-exchange volume (dark pool + OTC)
May 18, 2026
short_volume
Short Volume: PALI — 65.1% short (0.9M / 1.4M)
Short: 892,366 | Exempt: 138 | TRF Vol: 1,370,343 | Short Ratio: 65.1% | Off-exchange volume (dark pool + OTC)
May 15, 2026
short_volume
Short Volume: PALI — 65.6% short (0.6M / 0.9M)
Short: 564,968 | Exempt: 0 | TRF Vol: 861,195 | Short Ratio: 65.6% | Off-exchange volume (dark pool + OTC)
May 12, 2026
earnings
Palisade Bio Reports First Quarter 2026 Financial Results and Highlights Continued Clinical Progress of PALI-2108
<p align="center"><i>Advancing potentially best-in-class once-daily oral, locally-activated PDE4 inhibitor prodrug for treatment of IBD</i></p>
May 11, 2026
earnings_calendar
PALI Q1 2026 Earnings Scheduled — 2026-05-11
May 5, 2026
other
Palisade Bio Reports Additional Phase 1a/b Data Demonstrating Colon-Targeted Exposure and Sustained IC90 Coverage Supporting Once-Daily Dosing in Ulcerative Colitis
<p align="center"><i>Data demonstrate colon tissue PDE4/cAMP pathway modulation and sustained active metabolite exposure above IC90 across the dosing
Apr 16, 2026
other
Palisade Bio Announces Abstract Selected for Poster Presentation at Digestive Disease Week (DDW) 2026
<p align="center"><i>Poster presentation scheduled for Tuesday, May 5th at 12:30 PM CDT</i></p>
Mar 30, 2026
other
Palisade Bio Reports Positive Topline Data from Phase 1b Clinical Study of PALI-2108 in Fibrostenotic Crohn’s Disease
<p align="justify"><strong>Carlsbad, CA, March 30, 2026 (GLOBE NEWSWIRE) -- </strong>Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”)
Mar 23, 2026
earnings_calendar
PALI Q4 2025 Earnings After Market Close — 2026-03-23