PSTV

PLUS THERAPEUTICS, INC.

Nasdaq · Surgical & Medical Instruments & Apparatus · Inc. DE · CIK 0001095981
$5.41 -5.91% $39.5M
High Impact Filing (7/10)
Vol
Market Cap$39.5M
Cap SizeNano Cap
Analyst ConsensusStrong Buy (90%)
Inst. Holders3 funds
Inst. Value$1.2M
Inst. Activity2 buys / 0 sells
Reddit Sentiment63° Warm
SEC Reports5
Press Releases4
Exchange Nasdaq·Sector Surgical & Medical Instruments & Apparatus·Inc. DE·CIK 0001095981·Prev Close $5.75

Recent Activity

Jun 5, 2026 SEC
Plus Therapeutics filed Pre-Effective Amendment No. 1 to its Form S-3 shelf registration (File No. 333-296411) as an exh
S-3/A — Impact 3/10
Jun 4, 2026 other
Plus Therapeutics Announces CAP Accreditation of CNSide® Diagnostics Clinical Laboratory
CAP accreditation, widely recognized as the gold standard in laboratory quality assurance, complemen
May 19, 2026 Press
Plus Therapeutics announced a strategic partnership with Ephemeral Technologies, an AI firm founded by former Palantir h
Impact 4/10
May 15, 2026 SEC
Plus Therapeutics reported Q1 2026 EPS of -$1.05, a 19.2% miss vs consensus of -$0.87, on revenue of $1.0M (grant + CNSi
PRESS-RELEASE — Impact 6/10
May 14, 2026 Insider
Clowes Howard sold 3,686 shares
Director @ $0.00 ($0.00)
May 14, 2026 Insider
HEDRICK MARC H sold 23,834 shares
Chief Executive Officer @ $0.00 ($0.00)
May 14, 2026 Insider
Sims Andrew John Hugh MacIntyre sold 3,443 shares
Chief Financial Officer @ $0.00 ($0.00)
Apr 21, 2026 SEC
Plus Therapeutics (PSTV) announced it has regained compliance with Nasdaq's minimum bid price requirement of $1.00 per s
8-K — Impact 4/10

Price Targets

$38.00 +602.4% upside Strong Buy
Current $5.41 Low $12.00 Median $37.50 High $65.00 4 analysts
$12.00 $65.00

Analyst Ratings

Strong Buy90% buy · 10 analysts
2Strong Buy
7Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Apr 9, 2026 Ascendiant Capital MAINTAIN Buy → Buy
Mar 31, 2026 D. Boral Capital DOWNGRADE Buy → Hold
Mar 19, 2026 D. Boral Capital MAINTAIN Buy → Buy
Jan 23, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
Jan 22, 2026 D. Boral Capital MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.87 $-0.93 — $-0.79 -435% YoY 3
Next Q $-0.85 $-0.89 — $-0.80 15% YoY 3
Current FY $-3.87 $-4.78 — $-3.39 -1234% YoY 4
Next FY $-2.37 $-2.69 — $-1.98 39% YoY 4

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$1.2MADD
BANK OF AMERICA CORP$648.00ADD
WELLS FARGO & COMPANY/MN$27.00NEAR_EXIT

Recent Insider Trades

DateInsiderTypeValue
May 14, 2026Clowes HowardA$0.00
May 14, 2026HEDRICK MARCA$0.00
May 14, 2026Sims AndrewA$0.00
May 14, 2026HEDRICK MARCA$0.00
May 14, 2026Clowes HowardA$0.00

Reddit Sentiment

63°
Warm
Bearish Neutral Bullish
15 mentions 7 bullish 2 bearish
3 institutional holders with $1.2M total value (2,280,732 shares) as of 2025-Q4. Top holders: VANGUARD, BANK, WELLS. Net buying activity: 2 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC2,279,414$1.2M99.9%ADD +57.5%
2BANK OF AMERICA CORP /DE/1,265$648.000.1%ADD +52.2%
3WELLS FARGO & COMPANY/MN53$27.000.0%NEAR_EXIT -85.2%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
VANGUARD GROUP INCADD1,446,8272,279,414+57.5%$1.2M2025-Q4
BANK OF AMERICA CORP /DE/ADD8311,265+52.2%$648.002025-Q4
VANGUARD GROUP INCDOUBLED32,5411,446,827+4346.2%$989.6K2025-Q3
UBS Group AGDOUBLED87,638623,874+611.9%$426.7K2025-Q3
BANK OF AMERICA CORP /DE/DOUBLED158831+425.9%$567.002025-Q3
WELLS FARGO & COMPANY/MNNEAR_EXIT35753-85.2%$36.002025-Q3
UBS Group AGDOUBLED33,43787,638+162.1%$30.5K2025-Q2
BANK OF AMERICA CORP /DE/DOUBLED50158+216.0%$55.002025-Q2
UBS Group AGNEW33,437$31.8K2025-Q1
8 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 14, 2026Clowes HowardDirectorA3,686$0.00$0.00
May 14, 2026HEDRICK MARC HChief Executive OfficerA23,834$0.00$0.00
May 14, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerA3,443$0.00$0.00
May 14, 2026HEDRICK MARC HChief Executive OfficerA23,834$0.00$0.00
May 14, 2026Clowes HowardDirectorA3,686$0.00$0.00
May 14, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerA3,443$0.00$0.00
May 14, 2026ANDREWS RONALD ASBURYDirectorA3,686$0.00$0.00
May 14, 2026ANDREWS RONALD ASBURYDirectorA3,686$0.00$0.00
May 14, 2026Guse KyleDirectorA3,686$0.00$0.00
May 14, 2026Guse KyleDirectorA3,686$0.00$0.00
May 14, 2026Hawkins Richard JDirectorA3,686$0.00$0.00
May 14, 2026Hawkins Richard JDirectorA3,686$0.00$0.00
May 14, 2026van Es-Johansson AnDirectorA3,686$0.00$0.00
May 14, 2026van Es-Johansson AnDirectorA3,686$0.00$0.00
Apr 20, 2026Daniels Eric JosephChief Development OfficerA20,000$0.00$0.00
Apr 20, 2026Daniels Eric JosephChief Development OfficerA20,000$0.00$0.00
Apr 1, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerM38,323$0.00$0.00
Apr 1, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerM38,323$0.00$0.00
Apr 1, 2026HEDRICK MARC HChief Executive OfficerM159,681$0.00$0.00
Apr 1, 2026HEDRICK MARC HChief Executive OfficerM159,681$0.00$0.00
Feb 25, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerA349,542$0.00$0.00
Feb 25, 2026Sims Andrew John Hugh MacIntyreChief Financial OfficerA349,541$0.00$0.00
Feb 25, 2026HEDRICK MARC HChief Executive OfficerA2,419,582$0.00$0.00
Feb 25, 2026HEDRICK MARC HChief Executive OfficerA2,419,582$0.00$0.00
Current analyst consensus: Strong Buy (90% buy). Based on 10 analysts: 2 strong buy, 7 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$38.00 mean target +602.4% upside Strong Buy (1.25)
$12.00 Low $65.00 High
MetricValue
Current Price$5.41
Target Low$12.00
Target Mean$38.00
Target Median$37.50
Target High$65.00
# Analysts4
RecommendationStrong Buy (1.25)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.87 $-0.93 $-0.79 -435.4% 1↑ 1↓ $0.0B -20.1% 3
Next Q
2026-09-30
$-0.85 $-0.89 $-0.80 15.0% 1↑ 1↓ $0.0B 4.9% 3
Current FY
2026-12-31
$-3.87 $-4.78 $-3.39 -1234.5% 1↑ 1↓ $0.0B 35.4% 4
Next FY
2027-12-31
$-2.37 $-2.69 $-1.98 38.9% 1↑ 1↓ $0.0B 171.1% 4

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.870
7d ago$-0.880+0.010
30d ago$0.000-0.870
60d ago$-0.813-0.057
90d ago$-0.750-0.120
3 analyst firms have rated this stock: 0 upgrades, 1 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Apr 9, 2026 Ascendiant Capital MAINTAIN Buy Buy
Mar 31, 2026 D. Boral Capital DOWNGRADE Buy Hold
Mar 19, 2026 D. Boral Capital MAINTAIN Buy Buy
Jan 23, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 22, 2026 D. Boral Capital MAINTAIN Buy Buy
Jan 8, 2026 D. Boral Capital MAINTAIN Buy Buy
Dec 11, 2025 D. Boral Capital MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20262710090%
May 1, 20262720082%
Apr 1, 20262720082%
Mar 1, 20262810091%
Feb 1, 20262710090%
Jan 1, 20262710090%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

63°
Warm
Bearish Neutral Bullish
15 mentions 7 bullish 2 bearish 14 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 20, 2026160° Warm101
May 20, 2026160° Warm101
Apr 28, 2026160° Warm101
Apr 28, 2026160° Warm101
Apr 13, 2026160° Warm101
Apr 10, 2026160° Warm101
Apr 10, 2026160° Warm101
Apr 9, 2026150° Neutral001
Apr 9, 2026150° Neutral001
Apr 7, 2026140° Cool011
Apr 7, 2026140° Cool011
Apr 2, 2026144° Neutral001
Apr 2, 2026144° Neutral001
Feb 20, 2026250° Neutral002

Recent Reddit Threads

r/pennystocks Bullish 1mo ago
PSTV : True Significance Additional Payer Contract Today
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Bearish 1mo ago
PSTV : A realistic 10-bagger from current levels.
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Bullish 16d 18h ago
PSTV Bright Future!
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Bullish 1mo ago
$PSTV ready for a 10x bagger
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Neutral 1mo ago
PSTV genuinely has ample potential for a 10x upside. (2)
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Bullish 1mo ago
PSTV: Still holds more than 5x upside potential from current levels.
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Neutral 3mo ago
Just read up on $PSTV here but...... what's the catch? (if any)
▲ 1 💬 0 ⚡ 0.0
r/pennystocks Neutral 3mo ago
Just read up on $PSTV here but...... what's the catch? (if any)
▲ 1 💬 0 ⚡ 0.0
Jun 4, 2026
other
Plus Therapeutics Announces CAP Accreditation of CNSide® Diagnostics Clinical Laboratory
CAP accreditation, widely recognized as the gold standard in laboratory quality assurance, complements CNSide Diagnostics' existing CLIA certification
May 26, 2026
other
Plus' CNSide Diagnostic Platform Demonstrates Substantial Healthcare Cost Reduction in Patients with Leptomeningeal Metastases
<p align="center"><em>Plus and Harvard analysis shows CNSide enables early diagnosis and better clinical decision-making </em><br><em>reducing healthc
May 19, 2026
contract
Plus Therapeutics Partners with Ephemeral Technologies to Deploy AI Execution Platform for CNS Oncology
<p align="center"><em>Partnership to deliver a novel AI-native integrated CNS oncology platform</em></p>
May 15, 2026
earnings
Plus Therapeutics Reports First Quarter 2026 Financial Results and Provides Business Update on REYOBIQ™ Clinical Program and CNSide® Commercial Rollout
<p align="justify">HOUSTON, May 15, 2026 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq: PSTV) ("Plus" or the "Company"), a healthcare company
May 8, 2026
fda
Plus Therapeutics Announces Oral Presentation Highlighting REYOBIQ™ Clinical and Translational Data Demonstrating Favorable Safety, Survival, and Emerging Immunomodulation in Leptomeningeal Metastases
Plenary session at AANS underscores REYOBIQ’s potential as a differentiated targeted radiotherapeutic platform for CNS cancers <pre>Plenary session at
May 7, 2026
other
Plus Therapeutics Receives Medicare Enrollment Approval for CNSide Diagnostic
Enables billing under traditional Medicare and creates a pathway to ~35 million Medicare Advantage beneficiaries through future payer coverage decisio
Apr 28, 2026
contract
Plus Therapeutics Secures Blue Shield of California Coverage for CNSide® Cerebrospinal Fluid Assay for Metastatic CNS Cancer
Expands access by 6 million covered lives, advancing commercial momentum for CNSide® in metastatic CNS cancers <pre>Expands access by 6 million covere
Apr 23, 2026
other
Plus Therapeutics Initiates Manufacturing Activities with SpectronRx Under a Master Services Agreement to Support GMP Pivotal Trial Readiness for REYOBIQ™
<p align="justify">HOUSTON, April 23, 2026 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq: PSTV) (“Plus” or the “Company”), a healthcare compan
Apr 22, 2026
other
Plus Therapeutics Reports Granting of Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)
<p align="left">HOUSTON, April 22, 2026 (GLOBE NEWSWIRE) -- <u>Plus Therapeutics, Inc.</u> (Nasdaq: <u>PSTV</u>) (the “Company”), a healthcare compa
Apr 21, 2026
other
Plus Therapeutics Regains Compliance with Nasdaq Minimum Bid Price Requirement
<p>HOUSTON, April 21, 2026 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq: PSTV) (the “Company”), a healthcare company developing and commercia
Apr 15, 2026
other
Plus Therapeutics Appoints Randy H. Goodman, PhD, MHA, as Vice President of Value Strategy &amp; HEOR to Advance Market Access and Commercial Execution
Health economics and reimbursement expert brings over two decades of experience in payer strategy, value-based pricing, and health policy supporting C
Apr 9, 2026
other
Plus Therapeutics Appoints Eric J. Daniels, M.D., MBA, as Chief Development Officer to Advance Clinical Pipeline
Seasoned biotech executive brings deep experience across clinical development, regulatory strategy, and corporate operations, strengthening execution
Apr 9, 2026
short_interest
FTD: PSTV — 217,227 shares ($0.7M) failed to deliver
Settlement: 20260409, Price: $3.17, FTD Value: $688,609.59, PLUS THERAPEUTICS INC COM PAR
Apr 8, 2026
other
Plus Therapeutics Granted U.S. FDA Orphan Drug Designation to REYOBIQ™ in Pediatric Malignant Gliomas
<p align="justify">HOUSTON, April 08, 2026 (GLOBE NEWSWIRE) -- <a href="https://www.globenewswire.com/Tracker?data=CAqq1nuSSPrOuIhfN2Rm7V4_uk4JmrwWG
Apr 8, 2026
short_interest
FTD: PSTV — 274,728 shares ($0.8M) failed to deliver
Settlement: 20260408, Price: $2.92, FTD Value: $802,205.76, PLUS THERAPEUTICS INC COM PAR