SPRB

SPRUCE BIOSCIENCES, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001683553
$49.32 -2.20% $134.9M
3 New Institutional Positions
Vol
Market Cap$134.9M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (91%)
Inst. Holders3 funds
Inst. Value$1.6M
Inst. Activity3 buys / 0 sells
SEC Reports4
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001683553·Prev Close $50.43

Recent Activity

May 21, 2026 Insider
SPIEGELMAN DANIEL K sold 1,700 shares
Director @ $0.00 ($0.00)
May 21, 2026 Insider
GREY MICHAEL G sold 1,700 shares
Executive Chairman @ $0.00 ($0.00)
May 21, 2026 Insider
Barretto-Ko Percival sold 1,700 shares
Director @ $0.00 ($0.00)
May 13, 2026 SEC
Spruce Biosciences reported Q1 2026 net loss of $12.3M ($(8.94)/share), missing consensus EPS of $(7.32) by 22%. Cash an
8-K — Impact 5/10
May 13, 2026 earnings_calendar
SPRB Q1 2026 Earnings After Market Close — 2026-05-13
Apr 21, 2026 SEC
Spruce Biosciences is raising $59.9 million through a public offering of 1.15 million shares and pre-funded warrants for
424B5 — Impact 5/10
Apr 20, 2026 SEC
Spruce Biosciences is conducting a public offering of common stock and pre-funded warrants to raise capital, with net pr
424B5 — Impact 5/10
Inst.
VANGUARD GROUP INC — NEW
17,873 shares ($1.6M)

Price Targets

$154.17 +214.4% upside Strong Buy
Current $49.03 Low $120.00 Median $145.00 High $230.00 6 analysts
$120.00 $230.00

Analyst Ratings

Strong Buy91% buy · 11 analysts
4Strong Buy
6Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Jun 9, 2026 Jones Trading INITIATE Buy
Jun 1, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
May 14, 2026 Citizens MAINTAIN Market Outperform → Market Outperform
Apr 27, 2026 Craig-Hallum INITIATE Buy
Mar 10, 2026 Citizens MAINTAIN Market Outperform → Market Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-5.82 ▼ -1.7% $-8.18 — $-4.38 5
Next Q $-4.98 ▲ +20.0% $-5.24 — $-4.62 66% YoY 5
Current FY $-24.11 ▲ +1.7% $-28.73 — $-22.16 53% YoY 5
Next FY $9.27 ▲ +115.6% $-19.26 — $38.85 138% YoY 5

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$1.6MNEW
MORGAN STANLEY$33.8KDOUBLED
BANK OF AMERICA CORP$8.1KDOUBLED

Recent Insider Trades

DateInsiderTypeValue
May 21, 2026SPIEGELMAN DANIELA$0.00
May 21, 2026GREY MICHAELA$0.00
May 21, 2026Barretto-Ko PercivalA$0.00
May 21, 2026SIMPSON CAMILLAA$0.00
May 21, 2026Walbert KeliA$0.00
3 institutional holders with $1.6M total value (18,354 shares) as of 2025-Q4. Top holders: VANGUARD, MORGAN, BANK. Net buying activity: 3 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC17,873$1.6M97.4%NEW
2MORGAN STANLEY388$33.8K2.1%DOUBLED +295.9%
3BANK OF AMERICA CORP /DE/93$8.1K0.5%DOUBLED +3000.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
VANGUARD GROUP INCNEW17,873$1.6M2025-Q4
MORGAN STANLEYDOUBLED98388+295.9%$33.8K2025-Q4
BANK OF AMERICA CORP /DE/DOUBLED393+3000.0%$8.1K2025-Q4
RENAISSANCE TECHNOLOGIES LLCEXIT382,9000-100.0%$0.002025-Q2
VANGUARD GROUP INCEXIT843,8440-100.0%$0.002025-Q2
UBS Group AGEXIT116,4640-100.0%$0.002025-Q2
UBS Group AGADD86,045116,464+35.4%$33.8K2025-Q1
MORGAN STANLEYDOUBLED2,1337,396+246.7%$2.1K2025-Q1
RENAISSANCE TECHNOLOGIES LLCTRIM609,700405,900-33.4%$170.5K2024-Q4
UBS Group AGDOUBLED1386,045+661784.6%$36.1K2024-Q4
CITADEL ADVISORS LLCEXIT80,3530-100.0%$0.002024-Q4
6 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 21, 2026SPIEGELMAN DANIEL KDirectorA1,700$0.00$0.00
May 21, 2026GREY MICHAEL GExecutive ChairmanA1,700$0.00$0.00
May 21, 2026Barretto-Ko PercivalDirectorA1,700$0.00$0.00
May 21, 2026SIMPSON CAMILLA VDirectorA1,700$0.00$0.00
May 21, 2026Walbert KeliDirectorA1,700$0.00$0.00
Mar 9, 2026Hooks Corwin DaleChief Commercial OfficerA11,000$0.00$0.00

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (91% buy). Based on 11 analysts: 4 strong buy, 6 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$154.17 mean target +214.4% upside Strong Buy (1.17)
$120.00 Low $230.00 High
MetricValue
Current Price$49.03
Target Low$120.00
Target Mean$154.17
Target Median$145.00
Target High$230.00
# Analysts6
RecommendationStrong Buy (1.17)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-5.82 $-8.18 $-4.38 -1.7% 2↑ 1↓ $0.0B 0.0% 5
Next Q
2026-09-30
$-4.98 $-5.24 $-4.62 65.8% +20.0% 2↑ 1↓ $0.0B 0.0% 5
Current FY
2026-12-31
$-24.11 $-28.73 $-22.16 52.6% +1.7% 1↑ 2↓ $0.0B 0.0% 5
Next FY
2027-12-31
$9.27 $-19.26 $38.85 138.5% +115.6% 0↑ 3↓ $0.1B 0.0% 5

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-5.822
7d ago$-5.232-0.590
30d ago$-5.723-0.099
60d ago$-6.433+0.611
90d ago$-6.433+0.611
5 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 3 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jun 9, 2026 Jones Trading INITIATE Buy
Jun 1, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
May 14, 2026 Citizens MAINTAIN Market Outperform Market Outperform
Apr 27, 2026 Craig-Hallum INITIATE Buy
Mar 10, 2026 Citizens MAINTAIN Market Outperform Market Outperform
Mar 10, 2026 HC Wainwright & Co. REITERATE Buy Buy
Feb 19, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Dec 23, 2025 Oppenheimer INITIATE Outperform

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20264610091%
May 1, 20264610091%
Apr 1, 20264510090%
Mar 1, 20264510090%
Feb 1, 20263520080%
Jan 1, 20263430070%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 13, 2026
earnings_calendar
SPRB Q1 2026 Earnings After Market Close — 2026-05-13
May 11, 2026
earnings_calendar
SPRB Q1 2026 Earnings After Market Close — 2026-05-11
May 4, 2026
earnings_calendar
SPRB Q1 2026 Earnings After Market Close — 2026-05-04
Apr 17, 2026
short_interest
FTD: SPRB — 8,379 shares ($0.6M) failed to deliver
Settlement: 20260417, Price: $67.90, FTD Value: $568,934.1, SPRUCE BIOSCIENCES INC
Apr 16, 2026
short_interest
FTD: SPRB — 25,009 shares ($1.7M) failed to deliver
Settlement: 20260416, Price: $69.32, FTD Value: $1,733,623.88, SPRUCE BIOSCIENCES INC
Apr 15, 2026
short_interest
FTD: SPRB — 24,874 shares ($1.7M) failed to deliver
Settlement: 20260415, Price: $67.80, FTD Value: $1,686,457.2, SPRUCE BIOSCIENCES INC
Apr 14, 2026
short_interest
FTD: SPRB — 24,874 shares ($1.6M) failed to deliver
Settlement: 20260414, Price: $64.51, FTD Value: $1,604,621.74, SPRUCE BIOSCIENCES INC
Apr 13, 2026
short_interest
FTD: SPRB — 19,258 shares ($1.2M) failed to deliver
Settlement: 20260413, Price: $63.63, FTD Value: $1,225,386.54, SPRUCE BIOSCIENCES INC
Apr 10, 2026
short_interest
FTD: SPRB — 14,569 shares ($1.0M) failed to deliver
Settlement: 20260410, Price: $66.01, FTD Value: $961,699.69, SPRUCE BIOSCIENCES INC
Apr 9, 2026
short_interest
FTD: SPRB — 10,263 shares ($0.7M) failed to deliver
Settlement: 20260409, Price: $63.65, FTD Value: $653,239.95, SPRUCE BIOSCIENCES INC