TWST

Twist Bioscience Corp

Nasdaq · Biological Products, (No Diagnostic Substances) · Inc. DE · CIK 0001581280
$69.22 -6.37% $4.6B
Insider Selling Cluster (7 insiders)High Impact Filing (7/10)3 Institutional Exits
Vol
Market Cap$4.6B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (93%)
Inst. Holders6 funds
Inst. Value$245.3M
Inst. Activity1 buys / 3 sells
Insider Activity0B / 36S
Insider Net $-$9.3M
Reddit Sentiment70° Bullish
SEC Reports11
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·Inc. DE·CIK 0001581280·Prev Close $73.93

Recent Activity

Jun 5, 2026 short_volume
Short Volume: TWST — 56.8% short (0.6M / 1.0M)
Short: 583,794 | Exempt: 547 | TRF Vol: 1,026,996 | Short Ratio: 56.8% | Off-exchange volume (dark p
Jun 2, 2026 SEC
Four insiders at Twist Bioscience sold a total of $1.31M in open-market sales over a 7-day window, including the CEO (vi
CLUSTER — Impact 3/10
Jun 1, 2026 SEC
A cluster of insider selling at Twist Bioscience over the past week, led by CEO Emily Leproust who sold ~$3.2M in open-m
CLUSTER — Impact 3/10
May 29, 2026 Insider
Cho Dennis sold 14,205 shares
See Remarks @ $69.75 ($990.8K)
May 29, 2026 Insider
Laponis Adam sold 4,000 shares
Chief Financial Officer @ $70.00 ($280.0K)
May 28, 2026 SEC
A substantial insider selling cluster at Twist Bioscience, concentrated on May 21-26, 2026, with CEO Emily Leproust alon
CLUSTER — Impact 5/10
May 28, 2026 Insider
Starovasnik Melissa A. sold 2,500 shares
Director @ $68.00 ($170.0K)
Inst.
MORGAN STANLEY — TRIM
866,356 shares ($27.5M)

Price Targets

$64.38 -7.0% upside Sell
Current $69.22 Low $36.00 Median $65.50 High $80.00 8 analysts
$36.00 $80.00

Analyst Ratings

Strong Buy93% buy · 15 analysts
8Strong Buy
6Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 5, 2026 Leerink Partners UPGRADE Market Perform → Outperform
May 5, 2026 Barclays MAINTAIN Overweight → Overweight
May 5, 2026 Guggenheim MAINTAIN Buy → Buy
May 5, 2026 Baird MAINTAIN Outperform → Outperform
Apr 14, 2026 Barclays MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Next FY $-2.05 ▼ -8.8% $-2.05 — $-2.05 1
Current FY $-1.99 ▼ -19.6% $-2.17 — $-1.54 -53% YoY 8
Next Q $-0.36 ▼ -12.1% $-0.43 — $-0.25 19% YoY 7
Current Q $-0.47 ▼ -17.6% $-0.52 — $-0.37 -243% YoY 7

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$183.2M
MORGAN STANLEY$27.5MTRIM
CHARLES SCHWAB INVESTMENT MANAGEMENT$17.4MNEW
BANK OF AMERICA CORP$12.7MTRIM
WELLS FARGO & COMPANY/MN$2.4MADD

Recent Insider Trades

DateInsiderTypeValue
May 29, 2026Cho DennisSELL$990.8K
May 29, 2026Laponis AdamSELL$280.0K
May 28, 2026Starovasnik MelissaSELL$170.0K
May 28, 2026Leproust EmilyM$0.00
May 28, 2026Leproust EmilySELL$96.8K

Reddit Sentiment

70°
Bullish
Bearish Neutral Bullish
6 mentions 4 bullish 0 bearish
6 institutional holders with $245.3M total value (7,734,056 shares) as of 2025-Q4. Top holders: VANGUARD, MORGAN, CHARLES. Net selling activity: 3 institutions trimmed/exited vs 1 added.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC5,776,198$183.2M74.7%
2MORGAN STANLEY866,356$27.5M11.2%TRIM -41.9%
3CHARLES SCHWAB INVESTMENT MANAGEMENT INC548,392$17.4M7.1%NEW
4BANK OF AMERICA CORP /DE/399,354$12.7M5.2%TRIM -34.6%
5WELLS FARGO & COMPANY/MN74,819$2.4M1.0%ADD +60.0%
6FMR LLC68,937$2.2M0.9%TRIM -68.6%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYTRIM1,492,106866,356-41.9%$27.5M2025-Q4
WELLS FARGO & COMPANY/MNADD46,76074,819+60.0%$2.4M2025-Q4
FMR LLCTRIM219,53268,937-68.6%$2.2M2025-Q4
TWO SIGMA INVESTMENTS, LPEXIT73,7550-100.0%$0.002025-Q4
UBS Group AGDOUBLED216,597514,928+137.7%$14.5M2025-Q3
BANK OF AMERICA CORP /DE/TRIM688,332450,374-34.6%$12.7M2025-Q3
TWO SIGMA INVESTMENTS, LPTRIM115,95573,755-36.4%$2.1M2025-Q3
NORGES BANKEXIT20,0430-100.0%$0.002025-Q3
RENAISSANCE TECHNOLOGIES LLCEXIT13,8000-100.0%$0.002025-Q3
MORGAN STANLEYADD610,7421,200,446+96.6%$44.2M2025-Q2
BANK OF AMERICA CORP /DE/DOUBLED282,772688,332+143.4%$25.3M2025-Q2
NORGES BANKNEW20,043$737.4K2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEAR_EXIT193,90813,800-92.9%$507.7K2025-Q2
MORGAN STANLEYTRIM899,169610,742-32.1%$24.0M2025-Q1
RENAISSANCE TECHNOLOGIES LLCTRIM398,708193,908-51.4%$7.6M2025-Q1
TWO SIGMA INVESTMENTS, LPTRIM347,532140,676-59.5%$5.5M2025-Q1
NORGES BANKEXIT163,2100-100.0%$0.002025-Q1
RENAISSANCE TECHNOLOGIES LLCADD214,310398,708+86.0%$18.5M2024-Q4
UBS Group AGADD150,289227,636+51.5%$10.6M2024-Q4
WELLS FARGO & COMPANY/MNADD28,16437,886+34.5%$1.8M2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW524,942$23.7M2024-Q3
9 unique insiders with 36 transactions. Net insider value: -$9.3M ($0.00 bought, $9.3M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 29, 2026Cho DennisSee RemarksSELL14,205$69.75$990.8K
May 29, 2026Laponis AdamChief Financial OfficerSELL4,000$70.00$280.0K
May 28, 2026Starovasnik Melissa A.DirectorSELL2,500$68.00$170.0K
May 28, 2026Leproust Emily M.Chief Executive OfficerM16,470$0.00$0.00
May 28, 2026Leproust Emily M.Chief Executive OfficerSELL1,482$65.33$96.8K
May 28, 2026Leproust Emily M.Chief Executive OfficerM16,470$8.82$145.3K
May 27, 2026Leproust Emily M.Chief Executive OfficerM25,017$8.82$220.6K
May 27, 2026Leproust Emily M.Chief Executive OfficerSELL23,752$65.24$1.5M
May 27, 2026Leproust Emily M.Chief Executive OfficerM25,017$0.00$0.00
May 26, 2026Starovasnik Melissa A.DirectorSELL500$61.04$30.5K
May 26, 2026Leproust Emily M.Chief Executive OfficerM24,282$8.82$214.2K
May 26, 2026Leproust Emily M.Chief Executive OfficerSELL24,282$65.08$1.6M
May 26, 2026Leproust Emily M.Chief Executive OfficerM24,282$0.00$0.00
May 26, 2026WERNER ROBERT F.Chief Accounting OfficerSELL800$62.48$50.0K
May 21, 2026Green PaulaSVP of Human ResourcesSELL1,399$53.26$74.5K
May 21, 2026Finn Patrick JohnPresident and COOSELL4,160$53.26$221.5K
May 21, 2026Cho DennisSee RemarksSELL1,642$53.26$87.4K
May 21, 2026WERNER ROBERT F.Chief Accounting OfficerSELL688$53.26$36.6K
May 21, 2026Leproust Emily M.Chief Executive OfficerSELL6,888$53.26$366.8K
May 21, 2026Laponis AdamChief Financial OfficerSELL2,019$53.26$107.5K
May 12, 2026JOHANNESSEN JANDirectorM12,000$14.00$168.0K
May 12, 2026JOHANNESSEN JANDirectorSELL12,000$56.12$673.4K
May 12, 2026JOHANNESSEN JANDirectorM12,000$0.00$0.00
May 8, 2026WERNER ROBERT F.Chief Accounting OfficerSELL4,961$56.88$282.2K
May 4, 2026WERNER ROBERT F.Chief Accounting OfficerSELL164$57.15$9.4K
May 4, 2026Cho DennisSee RemarksSELL1,962$57.15$112.1K
May 4, 2026Finn Patrick JohnPresident and COOSELL2,844$57.15$162.5K
May 4, 2026Green PaulaSVP of Human ResourcesSELL1,116$57.15$63.8K
May 4, 2026Leproust Emily M.Chief Executive OfficerSELL5,127$57.15$293.0K
Apr 23, 2026Finn Patrick JohnPresident and COOSELL2,321$60.76$141.0K
Apr 22, 2026Leproust Emily M.Chief Executive OfficerM8,061$8.82$71.1K
Apr 22, 2026Leproust Emily M.Chief Executive OfficerSELL7,910$65.28$516.3K
Apr 22, 2026Leproust Emily M.Chief Executive OfficerM8,061$0.00$0.00
Apr 21, 2026Leproust Emily M.Chief Executive OfficerSELL1,610$65.01$104.7K
Apr 21, 2026Leproust Emily M.Chief Executive OfficerM1,610$8.82$14.2K
Apr 21, 2026Leproust Emily M.Chief Executive OfficerM1,610$0.00$0.00
Apr 17, 2026Laponis AdamChief Financial OfficerSELL4,000$60.00$240.0K
Apr 14, 2026Laponis AdamChief Financial OfficerSELL3,000$55.00$165.0K
Apr 9, 2026Laponis AdamChief Financial OfficerSELL2,597$49.89$129.6K
Apr 1, 2026Starovasnik Melissa A.DirectorSELL1,000$51.00$51.0K
Mar 20, 2026Green PaulaSVP of Human ResourcesSELL297$43.79$13.0K
Mar 20, 2026Cho DennisSee RemarksSELL354$43.79$15.5K
Mar 20, 2026Leproust Emily M.Chief Executive OfficerSELL1,742$43.79$76.3K
Mar 17, 2026CHESS ROBERTDirectorM10,000$11.89$118.9K
Mar 17, 2026CHESS ROBERTDirectorSELL10,000$47.00$470.0K
Mar 17, 2026CHESS ROBERTDirectorM10,000$0.00$0.00
Mar 6, 2026WERNER ROBERT F.Chief Accounting OfficerSELL246$46.43$11.4K
Mar 6, 2026Cho DennisSee RemarksSELL425$46.43$19.7K
Mar 6, 2026Green PaulaSVP of Human ResourcesSELL935$46.43$43.4K
Mar 6, 2026Leproust Emily M.Chief Executive OfficerSELL2,423$46.43$112.5K
11 SEC filing reports analyzed. Sentiment: 1 bullish, 5 bearish, 0 mixed, 5 neutral. Avg impact: 4.7/10.

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (93% buy). Based on 15 analysts: 8 strong buy, 6 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$64.38 mean target -7.0% upside Sell (1.33)
$36.00 Low $80.00 High
MetricValue
Current Price$69.22
Target Low$36.00
Target Mean$64.38
Target Median$65.50
Target High$80.00
# Analysts8
RecommendationSell (1.33)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Next FY
2027-09-30
$-2.05 $-2.05 $-2.05 -8.8% $0.5B 15.6% 1
Current FY
2026-09-30
$-1.99 $-2.17 $-1.54 -53.1% -19.6% 0↑ 7↓ $0.4B 18.6% 8
Next Q
2026-09-30
$-0.36 $-0.43 $-0.25 19.1% -12.1% 2↑ 4↓ $0.1B 18.7% 7
Current Q
2026-06-30
$-0.47 $-0.52 $-0.37 -243.1% -17.6% 0↑ 5↓ $0.1B 19.3% 7

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.472
7d ago$-0.431-0.042
30d ago$-0.402-0.071
60d ago$-0.399-0.073
90d ago$-0.393-0.079
12 analyst firms have rated this stock: 2 upgrades, 0 downgrades, 4 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 5, 2026 Leerink Partners UPGRADE Market Perform Outperform
May 5, 2026 Barclays MAINTAIN Overweight Overweight
May 5, 2026 Guggenheim MAINTAIN Buy Buy
May 5, 2026 Baird MAINTAIN Outperform Outperform
Apr 14, 2026 Barclays MAINTAIN Overweight Overweight
Apr 6, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
Mar 30, 2026 Guggenheim MAINTAIN Buy Buy
Feb 3, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
Feb 3, 2026 Barclays MAINTAIN Overweight Overweight
Jan 26, 2026 Guggenheim MAINTAIN Buy Buy
Jan 8, 2026 TD Cowen MAINTAIN Buy Buy
Dec 15, 2025 Barclays MAINTAIN Overweight Overweight
Nov 17, 2025 Barclays MAINTAIN Overweight Overweight
Nov 4, 2025 Stephens & Co. INITIATE Overweight
Oct 7, 2025 Evercore ISI Group MAINTAIN Outperform Outperform
Oct 2, 2025 Barclays MAINTAIN Overweight Overweight
May 6, 2025 Goldman Sachs MAINTAIN Buy Buy
May 6, 2025 Guggenheim REITERATE Buy Buy
May 6, 2025 Baird MAINTAIN Outperform Outperform
May 6, 2025 JP Morgan MAINTAIN Underweight Underweight
Apr 10, 2025 Barclays MAINTAIN Overweight Overweight
Feb 4, 2025 Scotiabank MAINTAIN Sector Outperform Sector Outperform
Feb 4, 2025 JP Morgan MAINTAIN Underweight Underweight
Feb 4, 2025 Baird MAINTAIN Outperform Outperform
Dec 13, 2024 Wolfe Research INITIATE Outperform
Nov 26, 2024 TD Cowen REITERATE Buy Buy
Nov 19, 2024 Barclays MAINTAIN Overweight Overweight
Nov 19, 2024 Scotiabank MAINTAIN Sector Outperform Sector Outperform
Nov 19, 2024 Baird MAINTAIN Outperform Outperform
Oct 17, 2024 Leerink Partners MAINTAIN Market Perform Market Perform
Oct 1, 2024 Evercore ISI Group MAINTAIN Outperform Outperform
Aug 5, 2024 Barclays MAINTAIN Overweight Overweight
Aug 5, 2024 JP Morgan MAINTAIN Underweight Underweight
Aug 5, 2024 Baird MAINTAIN Outperform Outperform
Jul 9, 2024 Goldman Sachs MAINTAIN Buy Buy
Jun 28, 2024 Barclays MAINTAIN Overweight Overweight
Jun 13, 2024 TD Cowen MAINTAIN Buy Buy
Jun 5, 2024 Guggenheim INITIATE Buy
May 6, 2024 Scotiabank MAINTAIN Sector Outperform Sector Outperform
May 3, 2024 Evercore ISI Group MAINTAIN Outperform Outperform
May 3, 2024 Barclays MAINTAIN Overweight Overweight
May 3, 2024 Baird MAINTAIN Outperform Outperform
Apr 10, 2024 Barclays MAINTAIN Overweight Overweight
Feb 5, 2024 Scotiabank MAINTAIN Sector Outperform Sector Outperform
Jan 25, 2024 Barclays MAINTAIN Overweight Overweight
Jan 18, 2024 Goldman Sachs MAINTAIN Buy Buy
Jan 17, 2024 Goldman Sachs UPGRADE Neutral Buy
Sep 27, 2023 Berenberg INITIATE Buy
Aug 7, 2023 Barclays MAINTAIN Overweight Overweight
Jul 13, 2023 Goldman Sachs MAINTAIN Neutral Neutral

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20268610093%
May 1, 20267720088%
Apr 1, 20267730082%
Mar 1, 20267730082%
Feb 1, 20267730082%
Jan 1, 20267730082%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

70°
Bullish
Bearish Neutral Bullish
6 mentions 4 bullish 0 bearish 2 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Apr 24, 2026364° Warm203
Apr 24, 2026364° Warm203

Recent Reddit Threads

r/investing Bullish 1mo ago
TWST bull run coming. INVEST
▲ 1 💬 1 ⚡ 0.5
r/investing Neutral 1mo ago
TWST ticker symbol. INVEST
▲ 1 💬 1 ⚡ 0.5
r/stocks Bullish 1mo ago
TWST , BIOSCIENCE BULLISH
▲ 1 💬 0 ⚡ 0.5
Jun 5, 2026
short_volume
Short Volume: TWST — 56.8% short (0.6M / 1.0M)
Short: 583,794 | Exempt: 547 | TRF Vol: 1,026,996 | Short Ratio: 56.8% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
short_volume
Short Volume: TWST — 57.0% short (0.3M / 0.5M)
Short: 299,805 | Exempt: 8,115 | TRF Vol: 525,783 | Short Ratio: 57.0% | Off-exchange volume (dark pool + OTC)
May 29, 2026
short_volume
Short Volume: TWST — 57.7% short (0.4M / 0.7M)
Short: 397,370 | Exempt: 19 | TRF Vol: 689,144 | Short Ratio: 57.7% | Off-exchange volume (dark pool + OTC)
May 26, 2026
short_volume
Short Volume: TWST — 59.1% short (0.4M / 0.6M)
Short: 363,726 | Exempt: 0 | TRF Vol: 615,112 | Short Ratio: 59.1% | Off-exchange volume (dark pool + OTC)
May 21, 2026
short_volume
Short Volume: TWST — 58.4% short (0.4M / 0.7M)
Short: 391,646 | Exempt: 0 | TRF Vol: 670,972 | Short Ratio: 58.4% | Off-exchange volume (dark pool + OTC)
May 20, 2026
short_volume
Short Volume: TWST — 55.0% short (0.3M / 0.6M)
Short: 310,384 | Exempt: 7 | TRF Vol: 564,094 | Short Ratio: 55.0% | Off-exchange volume (dark pool + OTC)
May 4, 2026
earnings_calendar
TWST Q2 2026 Earnings Scheduled — 2026-05-04
Apr 21, 2026
short_volume
Short Volume: TWST — 69.8% short (0.5M / 0.8M)
Short: 545,933 | Exempt: 274 | TRF Vol: 782,047 | Short Ratio: 69.8% | Off-exchange volume (dark pool + OTC)
Apr 15, 2026
short_volume
Short Volume: TWST — 55.0% short (0.3M / 0.5M)
Short: 286,670 | Exempt: 129 | TRF Vol: 520,969 | Short Ratio: 55.0% | Off-exchange volume (dark pool + OTC)
Apr 6, 2026
short_interest
FTD: TWST — 19,702 shares ($1.0M) failed to deliver
Settlement: 20260406, Price: $50.21, FTD Value: $989,237.42, TWIST BIOSCIENCE CORP COM (DE)
Mar 23, 2026
short_volume
Short Volume: TWST — 70.1% short (0.4M / 0.5M)
Short: 350,956 | Exempt: 0 | TRF Vol: 500,661 | Short Ratio: 70.1% | Off-exchange volume (dark pool + OTC)
Mar 18, 2026
short_interest
FTD: TWST — 15,212 shares ($0.7M) failed to deliver
Settlement: 20260318, Price: $47.28, FTD Value: $719,223.36, TWIST BIOSCIENCE CORP COM (DE)
Mar 11, 2026
short_interest
FTD: TWST — 11,626 shares ($0.5M) failed to deliver
Settlement: 20260311, Price: $45.40, FTD Value: $527,820.4, TWIST BIOSCIENCE CORP COM (DE)
Feb 23, 2026
short_interest
FTD: TWST — 371,330 shares ($18.0M) failed to deliver
Settlement: 20260223, Price: $48.59, FTD Value: $18,042,924.7, TWIST BIOSCIENCE CORP COM (DE)
Feb 11, 2026
short_interest
FTD: TWST — 29,526 shares ($1.4M) failed to deliver
Settlement: 20260211, Price: $49.06, FTD Value: $1,448,545.56, TWIST BIOSCIENCE CORP COM (DE)