XENE

Xenon Pharmaceuticals Inc.

Nasdaq · Pharmaceutical Preparations · Inc. A1 · CIK 0001582313
$51.21 -1.01% $5.1B
Insider Selling Cluster (2 insiders)
Vol
Market Cap$5.1B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (96%)
Inst. Holders7 funds
Inst. Value$487.6M
Inst. Activity2 buys / 1 sells
Insider Activity0B / 8S
Insider Net $-$1.7M
SEC Reports8
Press Releases2
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. A1·CIK 0001582313·Prev Close $51.73

Recent Activity

Jun 9, 2026 short_volume
Short Volume: XENE — 56.2% short (0.4M / 0.7M)
Short: 412,641 | Exempt: 0 | TRF Vol: 734,888 | Short Ratio: 56.2% | Off-exchange volume (dark pool
Jun 5, 2026 SEC
Director Gary Patou filed a Form 144 notice of intent to sell 1,322 shares of Xenon Pharmaceuticals common stock, valued
144 — Impact 2/10
Jun 5, 2026 Insider
Cannon Gillian sold 1,190 shares
Director @ $53.14 ($63.2K)
Jun 5, 2026 Insider
PATOU GARY sold 1,322 shares
Director @ $53.14 ($70.3K)
Jun 3, 2026 SEC
Xenon Pharmaceuticals filed an 8-K reporting the results of its June 2, 2026 annual meeting, where shareholders approved
8-K — Impact 3/10
Jun 3, 2026 Insider
Gover Justin D. sold 10,507 shares
Director @ $0.00 ($0.00)
May 7, 2026 SEC
Xenon Pharmaceuticals reported Q1 2026 net loss of $102.3M ($1.17/share) vs $65.0M ($0.83/share) in Q1 2025, with zero r
PRESS-RELEASE — Impact 6/10
Inst.
TWO SIGMA INVESTMENTS, LP — NEW
436,743 shares ($19.6M)

Price Targets

$79.30 +50.2% upside Strong Buy
Current $52.79 Low $56.00 Median $80.00 High $100.00 19 analysts
$56.00 $100.00

Analyst Ratings

Strong Buy96% buy · 26 analysts
11Strong Buy
14Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 27, 2026 JP Morgan MAINTAIN Overweight → Overweight
May 12, 2026 JP Morgan MAINTAIN Overweight → Overweight
May 8, 2026 RBC Capital MAINTAIN Outperform → Outperform
May 8, 2026 Needham MAINTAIN Buy → Buy
Mar 16, 2026 Wedbush MAINTAIN Outperform → Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-1.16 ▲ +1.3% $-1.46 — $-0.92 -9% YoY 14
Next Q $-1.19 ▲ +0.9% $-1.63 — $-0.95 -4% YoY 14
Current FY $-4.81 $-5.94 — $-3.88 -10% YoY 16
Next FY $-5.01 ▼ -5.9% $-6.08 — $-2.25 -4% YoY 16

Top Institutional Holders

FundValueMove
FMR LLC$399.8M
VANGUARD GROUP INC$29.8MDOUBLED
TWO SIGMA INVESTMENTS, LP$19.6MNEW
MORGAN STANLEY$13.2MDOUBLED
BANK OF AMERICA CORP$9.9MTRIM

Recent Insider Trades

DateInsiderTypeValue
Jun 5, 2026Cannon GillianSELL$63.2K
Jun 5, 2026PATOU GARYSELL$70.3K
Jun 3, 2026Gover JustinA$0.00
Jun 3, 2026Machado PatrickA$0.00
Jun 3, 2026Svoronos DawnA$0.00
7 institutional holders with $487.6M total value (10,878,690 shares) as of 2025-Q4. Top holders: FMR, VANGUARD, TWO. Net buying activity: 2 institutions added/increased vs 1 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1FMR LLC8,920,250$399.8M82.0%
2VANGUARD GROUP INC664,641$29.8M6.1%DOUBLED +159.5%
3TWO SIGMA INVESTMENTS, LP436,743$19.6M4.0%NEW
4MORGAN STANLEY294,332$13.2M2.7%DOUBLED +199.3%
5BANK OF AMERICA CORP /DE/221,368$9.9M2.0%TRIM -44.5%
6CHARLES SCHWAB INVESTMENT MANAGEMENT INC189,059$8.5M1.7%NEW
7WELLS FARGO & COMPANY/MN152,297$6.8M1.4%ADD +32.2%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
TWO SIGMA INVESTMENTS, LPNEW436,743$19.6M2025-Q4
WELLS FARGO & COMPANY/MNADD115,221152,297+32.2%$6.8M2025-Q4
RENAISSANCE TECHNOLOGIES LLCEXIT5,2000-100.0%$0.002025-Q4
BANK OF AMERICA CORP /DE/TRIM358,432199,106-44.5%$8.0M2025-Q3
UBS Group AGTRIM153,058106,744-30.3%$4.3M2025-Q3
RENAISSANCE TECHNOLOGIES LLCTRIM8,6005,200-39.5%$208.8K2025-Q3
VANGUARD GROUP INCDOUBLED336,514873,228+159.5%$27.3M2025-Q2
MORGAN STANLEYDOUBLED129,491387,596+199.3%$12.1M2025-Q2
BANK OF AMERICA CORP /DE/DOUBLED136,569358,432+162.5%$11.2M2025-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW192,242$6.0M2025-Q2
UBS Group AGADD105,333153,058+45.3%$4.8M2025-Q2
WELLS FARGO & COMPANY/MNADD65,912112,562+70.8%$3.5M2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEAR_EXIT154,7008,600-94.4%$269.2K2025-Q2
TWO SIGMA INVESTMENTS, LPEXIT236,9830-100.0%$0.002025-Q2
CITADEL ADVISORS LLCDOUBLED344,103701,288+103.8%$23.5M2025-Q1
RENAISSANCE TECHNOLOGIES LLCDOUBLED13,700154,700+1029.2%$5.2M2025-Q1
MORGAN STANLEYADD68,062129,491+90.3%$4.3M2025-Q1
UBS Group AGDOUBLED6,705105,333+1471.0%$3.5M2025-Q1
CITADEL ADVISORS LLCTRIM742,904344,103-53.7%$13.5M2024-Q4
MORGAN STANLEYTRIM239,94268,062-71.6%$2.7M2024-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM44,00013,700-68.9%$537.0K2024-Q4
UBS Group AGTRIM13,2906,705-49.5%$262.8K2024-Q4
10 unique insiders with 8 transactions. Net insider value: -$1.7M ($0.00 bought, $1.7M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 5, 2026Cannon GillianDirectorSELL1,190$53.14$63.2K
Jun 5, 2026PATOU GARYDirectorSELL1,322$53.14$70.3K
Jun 3, 2026Gover Justin D.DirectorA10,507$0.00$0.00
Jun 3, 2026Machado PatrickDirectorA10,507$0.00$0.00
Jun 3, 2026Svoronos DawnDirectorA1,593$0.00$0.00
Jun 3, 2026PATOU GARYDirectorA10,507$0.00$0.00
Jun 3, 2026Cannon GillianDirectorA10,507$0.00$0.00
Jun 3, 2026Cannon GillianDirectorA1,593$0.00$0.00
Jun 3, 2026Svoronos DawnDirectorA10,507$0.00$0.00
Jun 3, 2026GANNON STEVENDirectorA10,507$0.00$0.00
Jun 3, 2026GANNON STEVENDirectorA1,593$0.00$0.00
Jun 3, 2026GAROFALO ELIZABETH A.DirectorA10,507$0.00$0.00
Jun 3, 2026GAROFALO ELIZABETH A.DirectorA1,593$0.00$0.00
Jun 3, 2026Gover Justin D.DirectorA1,593$0.00$0.00
Jun 3, 2026PATOU GARYDirectorA1,593$0.00$0.00
Jun 3, 2026Machado PatrickDirectorA1,593$0.00$0.00
Jun 1, 2026Machado PatrickDirectorM2,645$0.00$0.00
Jun 1, 2026Cannon GillianDirectorM2,645$0.00$0.00
Jun 1, 2026Cannon GillianDirectorM2,645$0.00$0.00
Jun 1, 2026Svoronos DawnDirectorF1,416$53.41$75.6K
Jun 1, 2026GANNON STEVENDirectorM2,645$0.00$0.00
Jun 1, 2026Svoronos DawnDirectorM2,645$0.00$0.00
Jun 1, 2026Svoronos DawnDirectorM2,645$0.00$0.00
Jun 1, 2026GANNON STEVENDirectorF1,416$53.41$75.6K
Jun 1, 2026GANNON STEVENDirectorM2,645$0.00$0.00
Jun 1, 2026GAROFALO ELIZABETH A.DirectorM2,645$0.00$0.00
Jun 1, 2026GAROFALO ELIZABETH A.DirectorM2,645$0.00$0.00
Jun 1, 2026PATOU GARYDirectorM2,645$0.00$0.00
Jun 1, 2026Gover Justin D.DirectorM2,645$0.00$0.00
Jun 1, 2026Machado PatrickDirectorM2,645$0.00$0.00
Jun 1, 2026Gover Justin D.DirectorM2,645$0.00$0.00
Jun 1, 2026PATOU GARYDirectorM2,645$0.00$0.00
May 12, 2026GANNON STEVENDirectorM3,500$0.00$0.00
May 12, 2026GANNON STEVENDirectorM3,500$7.38$25.8K
Mar 13, 2026MORTIMER IANPRESIDENT & CEOSELL7,308$55.23$403.6K
Mar 13, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerSELL1,410$55.23$77.9K
Mar 13, 2026DiFabio AndreaChief Legal OfficerSELL1,342$55.23$74.1K
Mar 12, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerM3,750$0.00$0.00
Mar 12, 2026DiFabio AndreaChief Legal OfficerM3,750$0.00$0.00
Mar 12, 2026MORTIMER IANPRESIDENT & CEOM12,500$0.00$0.00
Mar 12, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerM3,750$0.00$0.00
Mar 12, 2026MORTIMER IANPRESIDENT & CEOM12,500$0.00$0.00
Mar 12, 2026DiFabio AndreaChief Legal OfficerM3,750$0.00$0.00
Mar 10, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerSELL2,771$60.11$166.6K
Mar 10, 2026MORTIMER IANPRESIDENT & CEOSELL11,269$60.11$677.4K
Mar 10, 2026DiFabio AndreaChief Legal OfficerSELL2,607$60.11$156.7K
Mar 9, 2026DiFabio AndreaChief Legal OfficerM7,500$0.00$0.00
Mar 9, 2026DiFabio AndreaChief Legal OfficerA7,500$0.00$0.00
Mar 9, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerM7,500$0.00$0.00
Mar 9, 2026KENNEY CHRISTOPHER JOHNChief Medical OfficerA7,500$0.00$0.00
Current analyst consensus: Strong Buy (96% buy). Based on 26 analysts: 11 strong buy, 14 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$79.30 mean target +50.2% upside Strong Buy (1.15)
$56.00 Low $100.00 High
MetricValue
Current Price$52.79
Target Low$56.00
Target Mean$79.30
Target Median$80.00
Target High$100.00
# Analysts19
RecommendationStrong Buy (1.15)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-1.16 $-1.46 $-0.92 -8.5% +1.3% 7↑ 4↓ $0.0B 0.0% 14
Next Q
2026-09-30
$-1.19 $-1.63 $-0.95 -3.9% +0.9% 8↑ 3↓ $0.0B 0.0% 14
Current FY
2026-12-31
$-4.81 $-5.94 $-3.88 -10.3% +0.3% 6↑ 7↓ $0.0B -72.5% 16
Next FY
2027-12-31
$-5.01 $-6.08 $-2.25 -4.1% -5.9% 4↑ 9↓ $0.0B 1602.7% 16

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-1.161
7d ago$-1.161
30d ago$-1.177+0.016
60d ago$-1.183+0.022
90d ago$-1.193+0.032
9 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 27, 2026 JP Morgan MAINTAIN Overweight Overweight
May 12, 2026 JP Morgan MAINTAIN Overweight Overweight
May 8, 2026 RBC Capital MAINTAIN Outperform Outperform
May 8, 2026 Needham MAINTAIN Buy Buy
Mar 16, 2026 Wedbush MAINTAIN Outperform Outperform
Mar 10, 2026 Wells Fargo MAINTAIN Overweight Overweight
Mar 10, 2026 Wedbush MAINTAIN Outperform Outperform
Mar 10, 2026 Deutsche Bank MAINTAIN Buy Buy
Mar 10, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Mar 9, 2026 Needham MAINTAIN Buy Buy
Mar 9, 2026 Baird MAINTAIN Outperform Outperform
Feb 27, 2026 Needham MAINTAIN Buy Buy
Feb 27, 2026 Wells Fargo MAINTAIN Overweight Overweight
Feb 24, 2026 Wolfe Research INITIATE Outperform
Jan 9, 2026 JP Morgan MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 2026111410096%
May 1, 2026111410096%
Apr 1, 2026111410096%
Mar 1, 2026111510096%
Feb 1, 2026101510096%
Jan 1, 2026101510096%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 9, 2026
short_volume
Short Volume: XENE — 56.2% short (0.4M / 0.7M)
Short: 412,641 | Exempt: 0 | TRF Vol: 734,888 | Short Ratio: 56.2% | Off-exchange volume (dark pool + OTC)
May 29, 2026
other
Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">VANCOUVER, British Columbia and BOSTON, MA, May 29, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuros
May 14, 2026
Clinical Trial
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
Phase Phase 3 — COMPLETED
May 12, 2026
earnings_calendar
XENE Q1 2026 Earnings After Market Close — 2026-05-12
May 7, 2026
earnings
Xenon Reports Q1 2026 Financial Results and Provides Business Update
<p>VANCOUVER, British Columbia and BOSTON, MA, May 07, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused b
May 7, 2026
earnings_calendar
XENE Q1 2026 Earnings After Market Close — 2026-05-07
Apr 19, 2026
fda
Xenon Presents Azetukalner Phase 3 X-TOLE2 Study Results and 48-Month Long-term Data in Focal Onset Seizures at 2026 AAN Annual Meeting
<p>VANCOUVER, British Columbia and BOSTON, MA, April 19, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused
Apr 15, 2026
earnings
Xenon to Present at Upcoming Investor Conferences
<p align="left">VANCOUVER, British Columbia and BOSTON, MA, April 15, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neurosci
Apr 7, 2026
earnings
Xenon to Highlight Phase 3 X-TOLE2 &amp; Long-Term Data for Azetukalner in Focal Onset Seizures at 2026 AAN Annual Meeting
<p align="left">VANCOUVER, British Columbia and BOSTON, MA, April 07, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neurosci
Apr 1, 2026
clinical_trial_readout
Results Pending: XEN1101 (Phase 3) — Completed 79d ago
Trial: A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures Sponsor: Xenon Pharmaceuticals Inc. Phase: Phase 3 | Completed: 2026-01-12
Mar 30, 2026
clinical_trial_readout
Results Pending: XEN1101 (Phase 3) — Completed 77d ago
Trial: A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures Sponsor: Xenon Pharmaceuticals Inc. Phase: Phase 3 | Completed: 2026-01-12
Mar 12, 2026
offering
Xenon Pharmaceuticals Announces Closing of $747.5 Million Upsized Public Offering Including Full Exercise of the Underwriters’ Option to Purchase Additional Shares
<p align="left">VANCOUVER, British Columbia and BOSTON, MA, March 12, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neurosci
Mar 11, 2026
offering
Xenon Pharmaceuticals Announces Pricing of Upsized $650.0 Million Public Offering
<p align="justify">VANCOUVER, British Columbia and BOSTON, March 10, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscie
Mar 10, 2026
short_interest
FTD: XENE — 48,878 shares ($3.1M) failed to deliver
Settlement: 20260310, Price: $62.76, FTD Value: $3,067,583.28, XENON PHARMACEUTICALS INC COMM
Mar 9, 2026
offering
Xenon Pharmaceuticals Announces Proposed Public Offering
<p>VANCOUVER, British Columbia and BOSTON, MA, March 09, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused
Mar 9, 2026
fda
Xenon Announces Positive Topline Data from Phase 3 X-TOLE2 Study of Azetukalner in Focal Onset Seizures (FOS)
<p>VANCOUVER, British Columbia and BOSTON, MA, March 09, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused