ZNTL

Zentalis Pharmaceuticals, Inc.

Nasdaq · Pharmaceutical Preparations · CIK 0001725160
$3.58 -2.19% $254.8M
Insider Selling Cluster (3 insiders)High Impact Filing (7/10)
Vol
Market Cap$254.8M
Cap SizeMicro Cap
Analyst ConsensusBuy (60%)
Inst. Holders6 funds
Inst. Value$13.0M
Inst. Activity0 buys / 2 sells
Insider Activity0B / 9S
Insider Net $-$134.7K
SEC Reports6
Press Releases4
Exchange Nasdaq·Sector Pharmaceutical Preparations·CIK 0001725160·Prev Close $3.66

Recent Activity

Jun 3, 2026 short_volume
Short Volume: ZNTL — 71.4% short (0.4M / 0.5M)
Short: 381,699 | Exempt: 1,156 | TRF Vol: 534,478 | Short Ratio: 71.4% | Off-exchange volume (dark p
Jun 1, 2026 Press
Zentalis granted 191,000 non-qualified stock options to two newly hired employees as an inducement for employment, with
Impact 2/10
May 26, 2026 Insider
Campbell Shannon sold 114,200 shares
Director @ $0.00 ($0.00)
May 21, 2026 SEC
Zentalis announced positive Phase 1b data for azenosertib plus paclitaxel in platinum-resistant ovarian cancer, with 39%
PRESS-RELEASE — Impact 6/10
May 21, 2026 SEC
Zentalis Pharmaceuticals announced Phase 1b MUIR trial data for azenosertib plus paclitaxel in platinum-resistant ovaria
8-K — Impact 6/10
May 12, 2026 SEC
Zentalis reported Q1 2026 results with a net loss of $35.4M ($0.50/share), slightly better than the $0.52 consensus. The
8-K — Impact 7/10
Feb 10, 2026 Insider
Vultaggio Vincent sold 6,894 shares
PAO and PFO @ $2.42 ($16.7K)
Feb 9, 2026 Insider
EASTLAND JULIA MARIE sold 889 shares
CEO & President @ $2.39 ($2.1K)

Price Targets

$6.50 +81.6% upside Strong Buy
Current $3.58 Low $4.00 Median $5.50 High $10.00 8 analysts
$4.00 $10.00

Analyst Ratings

Buy60% buy · 15 analysts
4Strong Buy
5Buy
6Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Apr 10, 2026 Guggenheim MAINTAIN Buy → Buy
Mar 27, 2026 Guggenheim REITERATE Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.46 ▲ +15.1% $-0.59 — $-0.30 -25% YoY 7
Next Q $-0.49 ▲ +15.0% $-0.64 — $-0.31 -32% YoY 7
Current FY $-1.74 ▲ +1.9% $-2.19 — $-1.33 3% YoY 5
Next FY $-1.56 $-2.32 — $-0.87 10% YoY 7

Top Institutional Holders

FundValueMove
RENAISSANCE TECHNOLOGIES LLC$3.9MADD
VANGUARD GROUP INC$3.9M
TWO SIGMA INVESTMENTS, LP$2.0MADD
BANK OF AMERICA CORP$1.8MDOUBLED
MORGAN STANLEY$1.1MTRIM

Recent Insider Trades

DateInsiderTypeValue
May 26, 2026Campbell ShannonA$0.00
Feb 10, 2026Vultaggio VincentSELL$16.7K
Feb 9, 2026EASTLAND JULIASELL$2.1K
Feb 9, 2026Vultaggio VincentSELL$8.1K
Feb 9, 2026Bruns IngmarSELL$801.62
6 institutional holders with $13.0M total value (9,624,965 shares) as of 2025-Q4. Top holders: RENAISSANCE, VANGUARD, TWO. Net selling activity: 2 institutions trimmed/exited vs 0 added.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1RENAISSANCE TECHNOLOGIES LLC2,883,745$3.9M30.0%ADD +52.0%
2VANGUARD GROUP INC2,855,590$3.9M29.7%
3TWO SIGMA INVESTMENTS, LP1,471,414$2.0M15.3%ADD +99.0%
4BANK OF AMERICA CORP /DE/1,367,254$1.8M14.2%DOUBLED +117.1%
5MORGAN STANLEY803,654$1.1M8.3%TRIM -42.9%
6FMR LLC243,308$328.5K2.5%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYTRIM1,407,829803,654-42.9%$1.1M2025-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCEXIT41,9810-100.0%$0.002025-Q4
RENAISSANCE TECHNOLOGIES LLCADD1,529,5532,325,355+52.0%$3.5M2025-Q3
BANK OF AMERICA CORP /DE/DOUBLED713,3151,548,781+117.1%$2.3M2025-Q3
MORGAN STANLEYADD1,097,6511,407,829+28.3%$2.1M2025-Q3
UBS Group AGDOUBLED129,468532,678+311.4%$804.3K2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEAR_EXIT299,09741,981-86.0%$63.4K2025-Q3
RENAISSANCE TECHNOLOGIES LLCADD826,0411,529,553+85.2%$1.8M2025-Q2
TWO SIGMA INVESTMENTS, LPADD549,3341,093,053+99.0%$1.3M2025-Q2
BANK OF AMERICA CORP /DE/TRIM1,130,092713,315-36.9%$827.4K2025-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INCTRIM486,499299,097-38.5%$347.0K2025-Q2
WELLS FARGO & COMPANY/MNNEAR_EXIT35,3672,278-93.6%$2.6K2025-Q2
MORGAN STANLEYTRIM1,713,1881,093,958-36.1%$1.7M2025-Q1
RENAISSANCE TECHNOLOGIES LLCADD539,345826,041+53.2%$1.3M2025-Q1
CITADEL ADVISORS LLCNEAR_EXIT3,231,02790,558-97.2%$144.0K2025-Q1
UBS Group AGDOUBLED29,528183,678+522.0%$556.5K2024-Q4
WELLS FARGO & COMPANY/MNADD27,30434,609+26.8%$104.9K2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW406,210$1.5M2024-Q3
4 unique insiders with 9 transactions. Net insider value: -$134.7K ($0.00 bought, $134.7K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 26, 2026Campbell ShannonDirectorA114,200$0.00$0.00
Feb 10, 2026Vultaggio VincentPAO and PFOSELL6,894$2.42$16.7K
Feb 9, 2026EASTLAND JULIA MARIECEO & PresidentSELL889$2.39$2.1K
Feb 9, 2026Vultaggio VincentPAO and PFOSELL3,379$2.39$8.1K
Feb 9, 2026Bruns IngmarChief Medical OfficerSELL335$2.39$801.62
Feb 6, 2026EASTLAND JULIA MARIECEO & PresidentSELL7,866$2.43$19.1K
Feb 6, 2026Vultaggio VincentPAO and PFOSELL29,951$2.43$72.8K
Feb 6, 2026Bruns IngmarChief Medical OfficerSELL2,962$2.43$7.2K
Feb 3, 2026Vultaggio VincentPAO and PFOSELL556$2.52$1.4K
Feb 2, 2026Vultaggio VincentPAO and PFOSELL2,540$2.55$6.5K
Current analyst consensus: Buy (60% buy). Based on 15 analysts: 4 strong buy, 5 buy, 6 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$6.50 mean target +81.6% upside Strong Buy (3.00)
$4.00 Low $10.00 High
MetricValue
Current Price$3.58
Target Low$4.00
Target Mean$6.50
Target Median$5.50
Target High$10.00
# Analysts8
RecommendationStrong Buy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.46 $-0.59 $-0.30 -24.7% +15.1% $0.0B 0.0% 7
Next Q
2026-09-30
$-0.49 $-0.64 $-0.31 -31.7% +15.0% $0.0B 0.0% 7
Current FY
2026-12-31
$-1.74 $-2.19 $-1.33 3.5% +1.9% 0↑ 1↓ $0.0B 0.0% 5
Next FY
2027-12-31
$-1.56 $-2.32 $-0.87 10.4% -0.0% 1↑ 3↓ $0.0B 0.0% 7

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.461
7d ago$-0.543+0.082
30d ago$-0.543+0.082
60d ago$-0.528+0.067
90d ago$-0.528+0.067
1 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Apr 10, 2026 Guggenheim MAINTAIN Buy Buy
Mar 27, 2026 Guggenheim REITERATE Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20264560060%
May 1, 20264560060%
Apr 1, 20264560060%
Mar 1, 20264560060%
Feb 1, 20264560060%
Jan 1, 20264560060%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 3, 2026
short_volume
Short Volume: ZNTL — 71.4% short (0.4M / 0.5M)
Short: 381,699 | Exempt: 1,156 | TRF Vol: 534,478 | Short Ratio: 71.4% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: ZNTL — 64.9% short (0.4M / 0.7M)
Short: 423,953 | Exempt: 300 | TRF Vol: 652,746 | Short Ratio: 64.9% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
regulatory
Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">SAN DIEGO, June 01, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innov
May 21, 2026
earnings
Zentalis Pharmaceuticals to Present Phase 1b MUIR Trial Data Showing Encouraging Clinical Activity and Manageable Safety Profile of Azenosertib Plus Paclitaxel in Platinum-Resistant Ovarian Cancer at ASCO 2026
<p align="justify">SAN DIEGO, May 21, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innova
May 13, 2026
other
Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences
<p align="justify">SAN DIEGO, May 13, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innova
May 12, 2026
earnings
Zentalis Pharmaceuticals Reports First Quarter 2026 Financial Results and Clinical Progress
<p align="justify">SAN DIEGO, May 12, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innova
May 12, 2026
earnings_calendar
ZNTL Q1 2026 Earnings Scheduled — 2026-05-12
May 1, 2026
other
Zentalis Pharmaceuticals Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
<p>SAN DIEGO, May 01, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing la
Apr 21, 2026
fda
Zentalis Pharmaceuticals Announces Abstract Acceptance at ASCO 2026 Featuring Azenosertib in Combination with Paclitaxel for Platinum-Resistant Ovarian Cancer
Results from Part 1 of the Phase 1b MUIR trial to be presented at annual meeting in June <pre>Results from Part 1 of the Phase 1b MUIR trial to be pre
Apr 17, 2026
fda
Zentalis Pharmaceuticals To Present Azenosertib Preclinical Data in Triple-Negative Breast Cancer and Real-World Analysis of Unmet Need in Cyclin E1-Positive Ovarian Cancer at AACR 2026
<p>SAN DIEGO, April 17, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing
Apr 1, 2026
other
Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p align="justify">SAN DIEGO, April 01, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology inno
Mar 26, 2026
earnings
Zentalis Pharmaceuticals Reports Full Year 2025 Financial Results and Operational Updates
<p align="justify">SAN DIEGO, March 26, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advan
Mar 24, 2026
earnings_calendar
ZNTL Q4 2025 Earnings After Market Close — 2026-03-24
Mar 17, 2026
routine
Zentalis Pharmaceuticals to Present Two Posters at the American Association for Cancer Research (AACR) Annual Meeting 2026
<p align="justify">SAN DIEGO, March 17, 2026 (GLOBE NEWSWIRE) -- Zentalis<sup>®</sup> Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology inno